SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5idu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		3 / 3 VAL A  52
TRP A  60
TRP A  31
 None
 1.30A 1c4dA-5iduA:
undetectable
1c4dB-5iduA:
undetectable		 1c4dA-5iduA:
4.91
1c4dB-5iduA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		4 / 5 ARG A  86
ALA A 258
ASP A  97
GLY A 262
 None
 1.16A 1e7bA-5iduA:
undetectable		 1e7bA-5iduA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		4 / 5 ARG A  86
ALA A 258
ASP A  97
GLY A 262
 None
 1.11A 1e7cA-5iduA:
3.0		 1e7cA-5iduA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		5 / 11 GLY A 106
SER A 107
ALA A 133
ALA A 131
VAL A  52
 None
 1.14A 1ukbA-5iduA:
undetectable		 1ukbA-5iduA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		5 / 12 SER A 127
VAL A 126
GLN A 233
ILE A 110
PHE A 177
 None
 1.25A 2vdyA-5iduA:
undetectable		 2vdyA-5iduA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		5 / 12 SER A 127
VAL A 126
GLN A 233
ILE A 110
PHE A 177
 None
 1.31A 2vdyB-5iduA:
undetectable		 2vdyB-5iduA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		4 / 6 ALA A  90
LEU A  89
ALA A  32
THR A  33
 None
 0.86A 3b6hA-5iduA:
0.0		 3b6hA-5iduA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		4 / 6 ALA A  90
LEU A  89
ALA A  32
THR A  33
 None
 0.88A 3b6hB-5iduA:
undetectable		 3b6hB-5iduA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		3 / 3 ARG A 221
ASP A 141
ASP A 165
 None
 0.86A 3jb2A-5iduA:
undetectable		 3jb2A-5iduA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		5 / 12 SER A 127
VAL A 126
GLN A 233
ILE A 110
PHE A 177
 None
 1.30A 4c49A-5iduA:
undetectable		 4c49A-5iduA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		5 / 12 SER A 127
VAL A 126
GLN A 233
ILE A 110
PHE A 177
 None
 1.23A 4c49B-5iduA:
undetectable		 4c49B-5iduA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		5 / 12 SER A 127
VAL A 126
GLN A 233
ILE A 110
PHE A 177
 None
 1.22A 4c49C-5iduA:
undetectable		 4c49C-5iduA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		5 / 12 SER A 127
VAL A 126
GLN A 233
ILE A 110
PHE A 177
 None
 1.28A 4c49D-5iduA:
undetectable		 4c49D-5iduA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		4 / 8 PHE A  17
ALA A 313
THR A 254
LEU A  84
 None
 0.80A 4ejgB-5iduA:
undetectable		 4ejgB-5iduA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		5 / 12 LEU A 112
ALA A 134
ILE A  77
LEU A 123
GLY A  74
 None
 1.14A 4l9qA-5iduA:
2.3		 4l9qA-5iduA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA703_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		4 / 4 LEU A  84
PHE A  17
LEU A 261
GLU A  87
 None
None
EDO  A 502 (-4.9A)
EDO  A 502 (-2.6A)
 1.32A 4p7nA-5iduA:
undetectable		 4p7nA-5iduA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN
(Paraburkholderia
phymatum) 		5 / 12 ILE A 162
ALA A 133
ALA A 134
GLY A 108
THR A 248
 None
 1.36A 5igpA-5iduA:
undetectable		 5igpA-5iduA:
24.59