SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ie6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 7 GLY A 240
PRO A 239
THR A 211
GLY A 213
 None
 0.76A 1usqA-5ie6A:
undetectable		 1usqA-5ie6A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 7 GLY A 240
PRO A 239
THR A 211
GLY A 213
 None
 0.77A 2jklA-5ie6A:
undetectable		 2jklA-5ie6A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 7 GLY A 240
PRO A 239
THR A 211
GLY A 213
 None
 0.78A 2jklC-5ie6A:
undetectable		 2jklC-5ie6A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 7 GLY A 240
PRO A 239
THR A 211
GLY A 213
 None
 0.79A 2jklD-5ie6A:
undetectable		 2jklD-5ie6A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 7 GLY A 240
PRO A 239
THR A 211
GLY A 213
 None
 0.79A 2jklF-5ie6A:
undetectable		 2jklF-5ie6A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA503_0
(OXIDOREDUCTASE,
FMN-BINDING)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 6 SER A  64
TYR A  16
TRP A  15
PHE A  56
 None
 1.01A 4awuA-5ie6A:
undetectable		 4awuA-5ie6A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 7 PRO A 244
SER A 247
VAL A 212
MET A 241
 None
 1.44A 4kmmA-5ie6A:
3.1		 4kmmA-5ie6A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 6 VAL A 212
HIS A 125
CYH A 124
HIS A 242
 None
None
None
ZHB  A 300 (-3.9A)
 1.48A 5hrqH-5ie6A:
undetectable
5hrqK-5ie6A:
undetectable
5hrqL-5ie6A:
undetectable		 5hrqH-5ie6A:
7.60
5hrqK-5ie6A:
7.04
5hrqL-5ie6A:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		5 / 12 LEU A 203
TRP A 210
LEU A 208
ALA A  77
LEU A 111
 None
 1.16A 5og9B-5ie6A:
undetectable		 5og9B-5ie6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 4 MET A 241
GLY A 240
HIS A 248
GLY A 160
 None
 0.91A 6fgdA-5ie6A:
3.0		 6fgdA-5ie6A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 4 LYS A 230
LEU A 200
ALA A 228
LEU A 203
 None
 1.11A 6gnrA-5ie6A:
undetectable		 6gnrA-5ie6A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 5ie6 ZEARALENONE
HYDROLASE
(Clonostachys
rosea) 		4 / 4 LYS A 230
LEU A 200
ALA A 228
LEU A 203
 None
 1.10A 6gnrB-5ie6A:
undetectable		 6gnrB-5ie6A:
18.94