SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ifg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5ifg ANTITOXIN HIGA
MRNA INTERFERASE
HIGB
(Escherichia
coli) 		4 / 6 ALA A   8
LEU B  34
ASP B  38
LEU B  41
 None
 0.95A 1mt1D-5ifgA:
undetectable
1mt1E-5ifgA:
undetectable		 1mt1D-5ifgA:
24.19
1mt1E-5ifgA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5ifg ANTITOXIN HIGA
MRNA INTERFERASE
HIGB
(Escherichia
coli) 		5 / 10 THR A   5
THR B  58
ALA B  55
ALA B  59
ALA B  33
 None
 1.06A 2f16K-5ifgA:
undetectable
2f16L-5ifgA:
undetectable		 2f16K-5ifgA:
16.19
2f16L-5ifgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5ifg ANTITOXIN HIGA
MRNA INTERFERASE
HIGB
(Escherichia
coli) 		5 / 10 THR A   5
THR B  58
ALA B  55
ALA B  59
ALA B  33
 None
 1.05A 2f16Y-5ifgA:
undetectable
2f16Z-5ifgA:
undetectable		 2f16Y-5ifgA:
16.19
2f16Z-5ifgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 5ifg MRNA INTERFERASE
HIGB
(Escherichia
coli) 		4 / 8 ILE A  82
ALA A  13
VAL A  62
VAL A  69
 None
 0.85A 3me6B-5ifgA:
undetectable		 3me6B-5ifgA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 5ifg MRNA INTERFERASE
HIGB
(Escherichia
coli) 		5 / 12 GLY A  63
VAL A  69
VAL A  24
ALA A  25
LEU A  26
 None
 1.08A 5kocA-5ifgA:
undetectable		 5kocA-5ifgA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5ifg ANTITOXIN HIGA
(Escherichia
coli) 		3 / 3 TYR B  91
ASP B  89
GLN B  90
 None
 0.78A 6g1pA-5ifgB:
undetectable		 6g1pA-5ifgB:
15.43