SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ifh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5ifh	HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE (Homo sapiens)	4 / 7	ALA H 92 THR H 91 VAL H 112 GLU H 89	None	0.73A	5ecmD-5ifhH: undetectable	5ecmD-5ifhH: 16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	5ifh	HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE (Homo sapiens)	4 / 7	ALA H 92 THR H 91 VAL H 112 GLU H 89	None	0.78A	5ecoD-5ifhH: undetectable	5ecoD-5ifhH: 16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_A_1GNA607_1 (PHIAB6 TAILSPIKE)	5ifh	HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE (Homo sapiens)	3 / 3	THR H 28 SER H 31 TYR H 32	None	0.70A	5jsdA-5ifhH: 2.9	5jsdA-5ifhH: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_B_1GNB618_1 (PHIAB6 TAILSPIKE)	5ifh	HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE (Homo sapiens)	3 / 3	THR H 28 SER H 31 TYR H 32	None	0.70A	5jsdB-5ifhH: undetectable	5jsdB-5ifhH: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_C_1GNC608_1 (PHIAB6 TAILSPIKE)	5ifh	HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE (Homo sapiens)	3 / 3	THR H 28 SER H 31 TYR H 32	None	0.69A	5jsdC-5ifhH: undetectable	5jsdC-5ifhH: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSE_A_1GNA608_1 (PHIAB6 TAILSPIKE)	5ifh	HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE (Homo sapiens)	3 / 3	THR H 28 SER H 31 TYR H 32	None	0.71A	5jseA-5ifhH: 2.3	5jseA-5ifhH: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSE_B_1GNB611_1 (PHIAB6 TAILSPIKE)	5ifh	HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE (Homo sapiens)	3 / 3	THR H 28 SER H 31 TYR H 32	None	0.71A	5jseB-5ifhH: 2.9	5jseB-5ifhH: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSE_C_1GNC611_1 (PHIAB6 TAILSPIKE)	5ifh	HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE (Homo sapiens)	3 / 3	THR H 28 SER H 31 TYR H 32	None	0.71A	5jseC-5ifhH: 2.9	5jseC-5ifhH: 15.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5ifh","HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE","Homo sapiens",4,"ALA H  92;THR H  91;VAL H 112;GLU H  89","None","0.73A","5ecmD-5ifhH:undetectable","5ecmD-5ifhH:16.78"],["5ECO_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","5ifh","HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE","Homo sapiens",4,"ALA H  92;THR H  91;VAL H 112;GLU H  89","None","0.78A","5ecoD-5ifhH:undetectable","5ecoD-5ifhH:16.78"],["5JSD_A_1GNA607_1","PHIAB6 TAILSPIKE","5ifh","HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE","Homo sapiens",3,"THR H  28;SER H  31;TYR H  32","None","0.70A","5jsdA-5ifhH:2.9","5jsdA-5ifhH:15.47"],["5JSD_B_1GNB618_1","PHIAB6 TAILSPIKE","5ifh","HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE","Homo sapiens",3,"THR H  28;SER H  31;TYR H  32","None","0.70A","5jsdB-5ifhH:undetectable","5jsdB-5ifhH:15.47"],["5JSD_C_1GNC608_1","PHIAB6 TAILSPIKE","5ifh","HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE","Homo sapiens",3,"THR H  28;SER H  31;TYR H  32","None","0.69A","5jsdC-5ifhH:undetectable","5jsdC-5ifhH:15.47"],["5JSE_A_1GNA608_1","PHIAB6 TAILSPIKE","5ifh","HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE","Homo sapiens",3,"THR H  28;SER H  31;TYR H  32","None","0.71A","5jseA-5ifhH:2.3","5jseA-5ifhH:15.47"],["5JSE_B_1GNB611_1","PHIAB6 TAILSPIKE","5ifh","HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE","Homo sapiens",3,"THR H  28;SER H  31;TYR H  32","None","0.71A","5jseB-5ifhH:2.9","5jseB-5ifhH:15.47"],["5JSE_C_1GNC611_1","PHIAB6 TAILSPIKE","5ifh","HEAVY CHAIN OF THE FAB FRAGMENT FROM BCR DERIVED FROM THE P11475 CLL CLONE","Homo sapiens",3,"THR H  28;SER H  31;TYR H  32","None","0.71A","5jseC-5ifhH:2.9","5jseC-5ifhH:15.47"]]