SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ifm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)
5ifm NON-POU
DOMAIN-CONTAINING
OCTAMER-BINDING
PROTEIN

(Homo
sapiens)
4 / 7 ASP A 228
GLN A 229
PRO A 226
GLU A 225
None
1.25A 3l2vA-5ifmA:
undetectable
3l2vA-5ifmA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)
5ifm NON-POU
DOMAIN-CONTAINING
OCTAMER-BINDING
PROTEIN

(Homo
sapiens)
3 / 3 LYS A 190
ARG A 153
ASP A 286
None
1.42A 3o7wA-5ifmA:
undetectable
3o7wA-5ifmA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)
5ifm NON-POU
DOMAIN-CONTAINING
OCTAMER-BINDING
PROTEIN

(Homo
sapiens)
3 / 3 HIS A 248
LYS A 243
PHE A 247
None
1.28A 5klaA-5ifmA:
undetectable
5klaA-5ifmA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)
5ifm NON-POU
DOMAIN-CONTAINING
OCTAMER-BINDING
PROTEIN

(Homo
sapiens)
5 / 12 LEU A 215
SER A 188
VAL A 179
GLY A 191
GLY A 189
None
1.16A 5nnaA-5ifmA:
undetectable
5nnaA-5ifmA:
18.62