SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ifn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_P_CHDP310_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	5ifn	PARASPECKLE COMPONENT 1 (Homo sapiens)	4 / 7	LYS A 161 LEU A 163 LEU A 223 PHE A 221	None	1.01A	2dysP-5ifnA: undetectable 2dysW-5ifnA: 3.1	2dysP-5ifnA: 17.50 2dysW-5ifnA: 12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_W_CHDW1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 3)	5ifn	PARASPECKLE COMPONENT 1 (Homo sapiens)	4 / 7	LYS A 161 LEU A 163 LEU A 223 PHE A 221	None	1.04A	2eimP-5ifnA: undetectable 2eimW-5ifnA: 3.2	2eimP-5ifnA: 17.50 2eimW-5ifnA: 12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZPH_A_PRLA501_0 (ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1)	5ifn	PARASPECKLE COMPONENT 1 (Homo sapiens)	4 / 7	ARG A 228 VAL A 230 LEU A 163 SER A 164	None	0.96A	4zphA-5ifnA: undetectable 4zphB-5ifnA: undetectable	4zphA-5ifnA: 18.94 4zphB-5ifnA: 23.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2DYS_P_CHDP310_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","5ifn","PARASPECKLE COMPONENT 1","Homo sapiens",4,"LYS A 161;LEU A 163;LEU A 223;PHE A 221","None","1.01A","2dysP-5ifnA:undetectable;2dysW-5ifnA:3.1","2dysP-5ifnA:17.50;2dysW-5ifnA:12.04"],["2EIM_W_CHDW1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 3","5ifn","PARASPECKLE COMPONENT 1","Homo sapiens",4,"LYS A 161;LEU A 163;LEU A 223;PHE A 221","None","1.04A","2eimP-5ifnA:undetectable;2eimW-5ifnA:3.2","2eimP-5ifnA:17.50;2eimW-5ifnA:12.04"],["4ZPH_A_PRLA501_0","ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR;ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1","5ifn","PARASPECKLE COMPONENT 1","Homo sapiens",4,"ARG A 228;VAL A 230;LEU A 163;SER A 164","None","0.96A","4zphA-5ifnA:undetectable;4zphB-5ifnA:undetectable","4zphA-5ifnA:18.94;4zphB-5ifnA:23.36"]]