SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ifw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)
5ifw TETHER CONTAINING
UBX DOMAIN FOR GLUT4

(Homo
sapiens)
3 / 3 ARG A 492
TYR A 493
LYS A 390
None
0.93A 1uujB-5ifwA:
undetectable
1uujB-5ifwA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)
5ifw TETHER CONTAINING
UBX DOMAIN FOR GLUT4

(Homo
sapiens)
4 / 7 LEU A 459
GLY A 405
ALA A 392
PHE A 406
None
0.99A 3tehB-5ifwA:
undetectable
3tehB-5ifwA:
13.59