SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ify'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.85A 1a7yA-5ifyA:
undetectable		 1a7yA-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.84A 1a7yB-5ifyA:
undetectable		 1a7yB-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.88A 1fjaC-5ifyA:
undetectable		 1fjaC-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.88A 1fjaD-5ifyA:
undetectable		 1fjaD-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  56
PRO A  83
THR A  81
 None
 0.79A 1i3wE-5ifyA:
undetectable		 1i3wE-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.80A 1i3wE-5ifyA:
undetectable		 1i3wE-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.83A 1i3wF-5ifyA:
undetectable		 1i3wF-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  56
PRO A  83
THR A  81
 None
 0.80A 1i3wG-5ifyA:
undetectable		 1i3wG-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.84A 1i3wG-5ifyA:
undetectable		 1i3wG-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.84A 1i3wH-5ifyA:
undetectable		 1i3wH-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 11 PHE A 135
ASP A 110
LEU A 108
PHE A 113
ALA A   9
 None
TRH  A 500 (-2.9A)
TRH  A 500 ( 4.2A)
None
None
 1.39A 1ju6A-5ifyA:
undetectable		 1ju6A-5ifyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 11 PHE A 135
LEU A 216
TYR A 170
GLY A 174
PHE A 150
 None
None
None
TRH  A 500 ( 4.0A)
None
 1.34A 1l5rA-5ifyA:
undetectable		 1l5rA-5ifyA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  56
PRO A  83
THR A  81
 None
 0.83A 1mnvD-5ifyA:
undetectable		 1mnvD-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.83A 1mnvD-5ifyA:
undetectable		 1mnvD-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 11 GLY A  74
ASP A  50
VAL A  51
ILE A  48
ILE A 256
 None
None
None
None
UMP  A 501 (-4.6A)
 0.95A 1n49B-5ifyA:
undetectable		 1n49B-5ifyA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  56
PRO A  83
THR A  81
 None
 0.85A 1ovfB-5ifyA:
undetectable		 1ovfB-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.85A 1qfiB-5ifyA:
undetectable		 1qfiB-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  56
PRO A  83
THR A  81
 None
 0.85A 1unjF-5ifyA:
undetectable		 1unjF-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.85A 1unjF-5ifyA:
undetectable		 1unjF-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  56
PRO A  83
THR A  81
 None
 0.85A 1unjL-5ifyA:
undetectable		 1unjL-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  56
PRO A  83
THR A  81
 None
 0.85A 1unmE-5ifyA:
undetectable		 1unmE-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.84A 1unmE-5ifyA:
undetectable		 1unmE-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  81
THR A  56
PRO A  83
 None
 0.86A 1unmF-5ifyA:
undetectable		 1unmF-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		4 / 8 ASN A 203
GLU A 161
VAL A 134
TYR A 176
 None
TRH  A 500 (-2.8A)
None
None
 1.17A 2fl5E-5ifyA:
undetectable
2fl5F-5ifyA:
undetectable		 2fl5E-5ifyA:
22.01
2fl5F-5ifyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		4 / 7 THR A 226
TYR A 176
PHE A 113
LEU A  88
 None
None
None
TRH  A 500 (-4.6A)
 1.00A 2hzqA-5ifyA:
undetectable		 2hzqA-5ifyA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		4 / 7 ASP A 201
SER A 204
SER A 158
GLU A 149
 None
 1.25A 3bc9A-5ifyA:
undetectable		 3bc9A-5ifyA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		4 / 5 TYR A 258
ALA A 272
TYR A  37
MET A  44
 None
 1.12A 3d91A-5ifyA:
undetectable		 3d91A-5ifyA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A 200
LYS A  25
GLU A 198
 TRH  A 500 (-4.5A)
TRH  A 500 ( 4.0A)
None
 0.62A 3ijdB-5ifyA:
undetectable		 3ijdB-5ifyA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  27
LEU A  67
GLY A  10
ALA A   9
SER A  55
 None
None
TRH  A 500 (-2.9A)
None
None
 0.98A 3nt1A-5ifyA:
undetectable		 3nt1A-5ifyA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  27
LEU A  67
GLY A  10
ALA A   9
SER A  55
 None
None
TRH  A 500 (-2.9A)
None
None
 0.98A 3nt1B-5ifyA:
undetectable		 3nt1B-5ifyA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  27
LEU A  67
GLY A  10
ALA A   9
SER A  55
 None
None
TRH  A 500 (-2.9A)
None
None
 1.06A 3pghD-5ifyA:
undetectable		 3pghD-5ifyA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  27
LEU A  67
GLY A  10
ALA A   9
SER A  55
 None
None
TRH  A 500 (-2.9A)
None
None
 1.01A 3rr3C-5ifyA:
undetectable		 3rr3C-5ifyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  27
LEU A  67
GLY A  10
ALA A   9
SER A  55
 None
None
TRH  A 500 (-2.9A)
None
None
 1.02A 3rr3D-5ifyA:
undetectable		 3rr3D-5ifyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 9 LEU A 106
ILE A   6
ILE A   7
TYR A  37
ILE A  54
 None
 0.98A 3zosA-5ifyA:
undetectable		 3zosA-5ifyA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 GLU A 234
ASP A 230
ASP A 225
 None
 0.72A 4gc9A-5ifyA:
undetectable		 4gc9A-5ifyA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 THR A  56
PRO A  83
THR A  81
 None
 0.82A 4hivD-5ifyA:
undetectable		 4hivD-5ifyA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 ILE A  53
ALA A  80
ARG A   3
LEU A  43
ILE A   7
 None
 1.04A 4kjlA-5ifyA:
undetectable		 4kjlA-5ifyA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		4 / 5 THR A  56
GLY A  11
HIS A  21
ASP A  59
 None
TRH  A 500 (-4.9A)
None
None
 1.25A 5c0oH-5ifyA:
undetectable		 5c0oH-5ifyA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 SER A 169
ALA A 171
VAL A 172
 None
None
TRH  A 500 (-3.9A)
 0.57A 5eypA-5ifyA:
undetectable		 5eypA-5ifyA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		5 / 12 LEU A  27
LEU A  67
GLY A  10
ALA A   9
SER A  55
 None
None
TRH  A 500 (-2.9A)
None
None
 1.09A 5jvzB-5ifyA:
undetectable		 5jvzB-5ifyA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		4 / 7 LEU A 242
VAL A 292
TYR A 283
GLU A 255
 None
None
None
UMP  A 501 (-3.3A)
 1.00A 5umwA-5ifyA:
undetectable
5umwF-5ifyA:
undetectable		 5umwA-5ifyA:
14.85
5umwF-5ifyA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		4 / 4 LEU A 118
LEU A 122
SER A  41
ALA A  46
 UMP  A 501 ( 4.4A)
None
UMP  A 501 ( 4.9A)
None
 0.91A 5uunA-5ifyA:
undetectable		 5uunA-5ifyA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Burkholderia
vietnamiensis) 		3 / 3 SER A 169
ALA A 171
VAL A 172
 None
None
TRH  A 500 (-3.9A)
 0.53A 5xiwC-5ifyA:
undetectable		 5xiwC-5ifyA:
16.34