SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ifz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5ifz RIBOSE 5-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		4 / 8 ILE A 117
ASN A 112
SER A 111
SER A 104
 None
 1.02A 2zw9B-5ifzA:
undetectable		 2zw9B-5ifzA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5ifz RIBOSE 5-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 9 ILE A  82
GLY A  83
VAL A 123
THR A  80
GLY A 120
 None
 1.34A 4acaB-5ifzA:
3.5
4acaC-5ifzA:
4.3		 4acaB-5ifzA:
17.46
4acaC-5ifzA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5ifz RIBOSE 5-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 GLY A  81
GLY A  83
THR A 118
ILE A  75
LEU A  31
 None
 1.30A 4n48A-5ifzA:
undetectable		 4n48A-5ifzA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 5ifz RIBOSE 5-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 LEU A  58
ALA A 121
ALA A  28
VAL A  77
GLY A  79
 None
 1.02A 4rn6B-5ifzA:
undetectable		 4rn6B-5ifzA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5ifz RIBOSE 5-PHOSPHATE
ISOMERASE
(Brucella
melitensis) 		5 / 12 GLY A  20
GLY A  24
GLY A  26
LYS A  57
LEU A  76
 None
 0.99A 5c0oH-5ifzA:
undetectable		 5c0oH-5ifzA:
20.31