SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ig0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		4 / 7 ARG A 433
PHE A 469
ARG A 452
GLU A 385
 SO4  A 501 ( 3.8A)
SO4  A 501 (-3.8A)
SO4  A 501 (-2.9A)
GOL  A 502 (-2.5A)
 1.17A 2c8aA-5ig0A:
undetectable		 2c8aA-5ig0A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		4 / 6 ARG A 433
PHE A 469
ARG A 452
GLU A 385
 SO4  A 501 ( 3.8A)
SO4  A 501 (-3.8A)
SO4  A 501 (-2.9A)
GOL  A 502 (-2.5A)
 1.17A 2c8aC-5ig0A:
undetectable		 2c8aC-5ig0A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		5 / 12 GLU A 383
GLU A 385
ALA A 364
ARG A 433
ARG A 452
 SO4  A 501 (-3.6A)
GOL  A 502 (-2.5A)
None
SO4  A 501 ( 3.8A)
SO4  A 501 (-2.9A)
 1.45A 2htqA-5ig0A:
undetectable		 2htqA-5ig0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		5 / 12 GLU A 383
GLU A 385
ALA A 364
ARG A 433
ARG A 452
 SO4  A 501 (-3.6A)
GOL  A 502 (-2.5A)
None
SO4  A 501 ( 3.8A)
SO4  A 501 (-2.9A)
 1.49A 4cpnB-5ig0A:
2.6		 4cpnB-5ig0A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		5 / 12 GLU A 383
GLU A 385
ALA A 364
ARG A 433
ARG A 452
 SO4  A 501 (-3.6A)
GOL  A 502 (-2.5A)
None
SO4  A 501 ( 3.8A)
SO4  A 501 (-2.9A)
 1.48A 4cpzA-5ig0A:
2.8		 4cpzA-5ig0A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		5 / 12 GLU A 383
GLU A 385
ALA A 364
ARG A 433
ARG A 452
 SO4  A 501 (-3.6A)
GOL  A 502 (-2.5A)
None
SO4  A 501 ( 3.8A)
SO4  A 501 (-2.9A)
 1.48A 4cpzB-5ig0A:
2.6		 4cpzB-5ig0A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		5 / 12 GLU A 383
GLU A 385
ALA A 364
ARG A 433
ARG A 452
 SO4  A 501 (-3.6A)
GOL  A 502 (-2.5A)
None
SO4  A 501 ( 3.8A)
SO4  A 501 (-2.9A)
 1.49A 4cpzD-5ig0A:
2.7		 4cpzD-5ig0A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		5 / 12 GLU A 383
GLU A 385
ALA A 364
ARG A 433
ARG A 452
 SO4  A 501 (-3.6A)
GOL  A 502 (-2.5A)
None
SO4  A 501 ( 3.8A)
SO4  A 501 (-2.9A)
 1.47A 4cpzE-5ig0A:
2.8		 4cpzE-5ig0A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		5 / 12 GLU A 383
GLU A 385
ALA A 364
ARG A 433
ARG A 452
 SO4  A 501 (-3.6A)
GOL  A 502 (-2.5A)
None
SO4  A 501 ( 3.8A)
SO4  A 501 (-2.9A)
 1.49A 4cpzF-5ig0A:
undetectable		 4cpzF-5ig0A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		5 / 12 GLU A 383
GLU A 385
ALA A 364
ARG A 433
ARG A 452
 SO4  A 501 (-3.6A)
GOL  A 502 (-2.5A)
None
SO4  A 501 ( 3.8A)
SO4  A 501 (-2.9A)
 1.48A 4cpzG-5ig0A:
2.6		 4cpzG-5ig0A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		4 / 8 VAL A 379
HIS A 397
TRP A 454
LEU A 359
 None
 1.05A 4jtrA-5ig0A:
undetectable		 4jtrA-5ig0A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		4 / 7 GLU A 450
TYR A 448
GLU A 385
ARG A 433
 None
GOL  A 502 (-3.0A)
GOL  A 502 (-2.5A)
SO4  A 501 ( 3.8A)
 1.04A 4mi4B-5ig0A:
undetectable
4mi4C-5ig0A:
undetectable		 4mi4B-5ig0A:
20.30
4mi4C-5ig0A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		4 / 8 GLU A 450
TYR A 448
GLU A 385
ARG A 433
 None
GOL  A 502 (-3.0A)
GOL  A 502 (-2.5A)
SO4  A 501 ( 3.8A)
 1.03A 4mj8B-5ig0A:
undetectable
4mj8C-5ig0A:
undetectable		 4mj8B-5ig0A:
19.44
4mj8C-5ig0A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 5ig0 CAMK/CAMK2 PROTEIN
KINASE
(Salpingoeca
rosetta) 		4 / 5 HIS A 470
GLU A 385
LEU A 360
VAL A 363
 None
GOL  A 502 (-2.5A)
None
SO4  A 501 (-4.4A)
 1.21A 6bc9A-5ig0A:
undetectable		 6bc9A-5ig0A:
18.24