SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ig3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 5ig3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA
(Homo
sapiens) 		4 / 4 ARG A 469
ALA A 379
ALA A 384
GLU A 383
 None
 1.20A 1e7bB-5ig3A:
undetectable		 1e7bB-5ig3A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 5ig3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA
(Homo
sapiens) 		4 / 7 PHE A 399
LEU A 357
MET A 372
LEU A 392
 None
 0.88A 1hk3A-5ig3A:
undetectable		 1hk3A-5ig3A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 5ig3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA
(Homo
sapiens) 		5 / 11 ARG A 346
ILE A 350
ILE A 429
HIS A 420
MET A 422
 None
 1.20A 2azyA-5ig3A:
undetectable		 2azyA-5ig3A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 5ig3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA
(Homo
sapiens) 		4 / 8 ALA A 379
ALA A 384
GLU A 383
LEU A 392
 None
 0.91A 2bxgA-5ig3A:
undetectable		 2bxgA-5ig3A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 5ig3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA
(Homo
sapiens) 		4 / 6 ALA A 360
ASP A 365
ARG A 433
MET A 377
 None
 1.16A 2ouzA-5ig3A:
undetectable		 2ouzA-5ig3A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 5ig3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA
(Homo
sapiens) 		4 / 6 ILE A 350
TYR A 431
ILE A 464
HIS A 456
 None
 0.81A 3eteA-5ig3A:
undetectable
3eteE-5ig3A:
undetectable		 3eteA-5ig3A:
15.95
3eteE-5ig3A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 5ig3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA
(Homo
sapiens) 		4 / 5 ILE A 350
TYR A 431
ILE A 464
HIS A 456
 None
 0.80A 3eteB-5ig3A:
undetectable
3eteC-5ig3A:
undetectable		 3eteB-5ig3A:
15.95
3eteC-5ig3A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 5ig3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA
(Homo
sapiens) 		4 / 7 ILE A 464
HIS A 456
ILE A 350
TYR A 431
 None
 0.81A 3eteD-5ig3A:
undetectable
3eteF-5ig3A:
undetectable		 3eteD-5ig3A:
15.95
3eteF-5ig3A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 5ig3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA
(Homo
sapiens) 		4 / 7 TYR A 369
ARG A 433
PHE A 467
GLU A 381
 None
 1.44A 4xzkA-5ig3A:
undetectable		 4xzkA-5ig3A:
25.10