SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ig5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 5ig5 CAMKII-B HUB
(Nematostella
vectensis) 		5 / 12 LEU A 392
LEU A 357
ASN A 464
ILE A 361
SER A 360
 None
 1.21A 2ydoA-5ig5A:
undetectable		 2ydoA-5ig5A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5ig5 CAMKII-B HUB
(Nematostella
vectensis) 		3 / 3 HIS A 395
SER A 360
ASN A 464
 None
 0.85A 3s8pB-5ig5A:
undetectable		 3s8pB-5ig5A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 5ig5 CAMKII-B HUB
(Nematostella
vectensis) 		5 / 11 TYR A 369
LEU A 357
VAL A 373
ASN A 464
ALA A 379
 None
 1.49A 4evrA-5ig5A:
undetectable		 4evrA-5ig5A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5ig5 CAMKII-B HUB
(Nematostella
vectensis) 		3 / 3 HIS A 395
SER A 360
ASN A 464
 None
 0.83A 5cprB-5ig5A:
undetectable		 5cprB-5ig5A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 5ig5 CAMKII-B HUB
(Nematostella
vectensis) 		4 / 8 SER A 360
ILE A 361
LEU A 357
LEU A 372
 None
 1.02A 5u4sB-5ig5A:
undetectable		 5u4sB-5ig5A:
19.43