SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ig9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		5 / 11 VAL A  70
ILE A 105
LEU A 108
LEU A  62
LEU A  64
 None
 1.14A 2a15A-5ig9A:
undetectable		 2a15A-5ig9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		4 / 7 ARG A  74
TYR A 277
PHE A 301
GLU A 300
 None
 1.13A 2qebA-5ig9A:
undetectable		 2qebA-5ig9A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		4 / 7 ARG A  74
TYR A 277
PHE A 301
GLU A 300
 None
 1.11A 2qebB-5ig9A:
undetectable		 2qebB-5ig9A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		5 / 12 HIS A 112
LEU A 321
VAL A  18
ILE A  19
LEU A 108
 None
 1.19A 3g9eA-5ig9A:
undetectable		 3g9eA-5ig9A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		3 / 3 TYR A 174
MET A  85
LEU A  94
 None
 0.83A 3vw1D-5ig9A:
undetectable		 3vw1D-5ig9A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		4 / 6 ILE A 116
TYR A  77
MET A  75
THR A   7
 None
 1.07A 3wg7A-5ig9A:
undetectable
3wg7J-5ig9A:
undetectable		 3wg7A-5ig9A:
20.38
3wg7J-5ig9A:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		4 / 5 ARG A  31
VAL A  18
LEU A  17
SER A  14
 None
 1.37A 4e1gA-5ig9A:
undetectable		 4e1gA-5ig9A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		4 / 6 ARG A  31
ASP A  57
ASP A  33
ARG A  36
 None
 1.09A 4kcnA-5ig9A:
undetectable		 4kcnA-5ig9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		4 / 6 ARG A  31
ASP A  57
ASP A  33
ARG A  36
 None
 1.10A 4kcnB-5ig9A:
undetectable		 4kcnB-5ig9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		5 / 12 LEU A  64
LEU A  45
ILE A 105
ALA A 106
ILE A 101
 None
 1.05A 5eypB-5ig9A:
undetectable		 5eypB-5ig9A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		4 / 7 LEU A 113
TYR A 277
THR A 219
LEU A 321
 None
 1.13A 5jq7B-5ig9A:
undetectable		 5jq7B-5ig9A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 5ig9 ATP GRASP LIGASE
(Microcystis
aeruginosa) 		6 / 10 TYR A 256
ILE A 262
THR A 227
ILE A 225
ILE A 218
ILE A 220
 None
 1.33A 5murE-5ig9A:
undetectable		 5murE-5ig9A:
13.58