SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ihr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 LEU A 979
LEU A 910
ASN A 911
GLN A 942
LEU A 952
 None
None
MAN  A1376 (-3.8A)
None
None
 1.39A 1a28B-5ihrA:
undetectable		 1a28B-5ihrA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 6 TRP A 307
GLY A 308
ASN A 938
PRO A 310
 None
MAN  A1917 (-3.3A)
None
None
 1.24A 1dedA-5ihrA:
11.0		 1dedA-5ihrA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 6 GLY A 809
ASP A 811
GLY A 157
TYR A 166
 None
 0.90A 1eswA-5ihrA:
9.3		 1eswA-5ihrA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 PHE A 148
TRP A  99
GLU A 103
 None
 1.06A 1mogA-5ihrA:
undetectable		 1mogA-5ihrA:
5.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 TYR A 260
ASN A 140
TYR A 355
GLY A 145
 GAL  A4001 ( 4.6A)
GAL  A4001 (-3.8A)
None
None
 1.26A 1mxgA-5ihrA:
10.1		 1mxgA-5ihrA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 TYR A 932
ASN A 958
TYR A 954
GLY A 956
 None
 1.23A 1mxgA-5ihrA:
10.1		 1mxgA-5ihrA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 GLU A 322
ASN A 320
TRP A 272
 MAN  A1626 (-3.7A)
MAN  A1627 (-3.7A)
None
 1.25A 1r15C-5ihrA:
1.8		 1r15C-5ihrA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 GLU A 322
ASN A 320
TRP A 272
 MAN  A1626 (-3.7A)
MAN  A1627 (-3.7A)
None
 1.23A 1r15D-5ihrA:
1.6		 1r15D-5ihrA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 GLU A 322
ASN A 320
TRP A 272
 MAN  A1626 (-3.7A)
MAN  A1627 (-3.7A)
None
 1.24A 1r15E-5ihrA:
undetectable		 1r15E-5ihrA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 GLU A 322
ASN A 320
TRP A 272
 MAN  A1626 (-3.7A)
MAN  A1627 (-3.7A)
None
 1.21A 1r15F-5ihrA:
undetectable		 1r15F-5ihrA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 ILE A 230
SER A  64
ILE A  62
LEU A  53
ILE A 193
 None
 1.02A 1rb3B-5ihrA:
undetectable		 1rb3B-5ihrA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 GLY A 888
TRP A 965
TYR A 892
PRO A 880
 None
 1.02A 1th6A-5ihrA:
undetectable		 1th6A-5ihrA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 5 TYR A 255
SER A 238
THR A 202
ASN A 242
 None
 1.49A 1yvpA-5ihrA:
undetectable		 1yvpA-5ihrA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 GLY A 888
TRP A 965
TYR A 892
PRO A 880
 None
 1.02A 2armA-5ihrA:
undetectable		 2armA-5ihrA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 SER A 756
TRP A 965
LEU A 683
GLU A 685
 None
 0.97A 2cdqB-5ihrA:
undetectable		 2cdqB-5ihrA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 9 GLY A 301
ILE A 344
ALA A 367
VAL A 368
PHE A 345
 None
 1.31A 2drdA-5ihrA:
undetectable		 2drdA-5ihrA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 ILE A 797
GLY A 801
GLY A 750
GLN A 748
 None
 0.72A 2wd9B-5ihrA:
undetectable		 2wd9B-5ihrA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 5 ILE A 114
PRO A  73
PHE A  70
PRO A  69
 None
 1.17A 3bjwC-5ihrA:
undetectable		 3bjwC-5ihrA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 GLY A 940
ILE A 939
PRO A 918
THR A 917
 NAG  A1914 (-3.3A)
NAG  A1915 (-4.7A)
None
NAG  A1914 (-3.7A)
 0.75A 3el9A-5ihrA:
undetectable		 3el9A-5ihrA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 GLY A 972
GLY A 883
LEU A 974
GLU A 886
ALA A 966
 None
 0.72A 3kkzA-5ihrA:
undetectable		 3kkzA-5ihrA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 GLY A 972
GLY A 883
LEU A 974
GLU A 886
ALA A 966
 None
 0.78A 3kkzB-5ihrA:
undetectable		 3kkzB-5ihrA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 GLY A 136
CYH A  92
PHE A  82
PHE A 120
 None
 1.07A 3ko0D-5ihrA:
undetectable
3ko0E-5ihrA:
undetectable		 3ko0D-5ihrA:
6.99
3ko0E-5ihrA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 PHE A  82
GLY A  89
PHE A  95
PHE A 120
 None
 1.06A 3ko0B-5ihrA:
undetectable
3ko0J-5ihrA:
undetectable		 3ko0B-5ihrA:
6.99
3ko0J-5ihrA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 GLY A  89
PHE A  95
PHE A 120
PHE A  82
 None
 1.13A 3ko0L-5ihrA:
undetectable
3ko0N-5ihrA:
undetectable		 3ko0L-5ihrA:
6.99
3ko0N-5ihrA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 GLY A 136
CYH A  92
PHE A  82
PHE A 120
 None
 1.00A 3ko0L-5ihrA:
undetectable
3ko0N-5ihrA:
undetectable		 3ko0L-5ihrA:
6.99
3ko0N-5ihrA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PHE A  82
GLY A  89
PHE A  95
PHE A 120
 None
 1.10A 3ko0K-5ihrA:
undetectable
3ko0S-5ihrA:
undetectable		 3ko0K-5ihrA:
6.99
3ko0S-5ihrA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PHE A 120
GLY A 136
CYH A  92
PHE A  82
 None
 1.04A 3ko0K-5ihrA:
undetectable
3ko0S-5ihrA:
undetectable		 3ko0K-5ihrA:
6.99
3ko0S-5ihrA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PHE A  82
GLY A  89
PHE A  95
PHE A 120
 None
 1.11A 3ko0R-5ihrA:
undetectable
3ko0T-5ihrA:
undetectable		 3ko0R-5ihrA:
6.99
3ko0T-5ihrA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PHE A 120
GLY A 136
CYH A  92
PHE A  82
 None
 1.06A 3ko0R-5ihrA:
undetectable
3ko0T-5ihrA:
undetectable		 3ko0R-5ihrA:
6.99
3ko0T-5ihrA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 5 ASN A 642
ALA A 619
ALA A 988
LYS A  84
 None
 1.38A 3kp2B-5ihrA:
undetectable		 3kp2B-5ihrA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 6 PHE A 388
TYR A 395
THR A 397
PHE A 427
 None
 1.33A 3ltwA-5ihrA:
undetectable		 3ltwA-5ihrA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_1
(YAEB-LIKE PROTEIN
RPA0152)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 5 HIS A 432
SER A 433
ASP A 410
THR A 441
 None
 1.18A 3okxA-5ihrA:
undetectable		 3okxA-5ihrA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_2
(YAEB-LIKE PROTEIN
RPA0152)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 5 HIS A 432
SER A 433
ASP A 410
THR A 441
 None
 1.18A 3okxB-5ihrA:
undetectable		 3okxB-5ihrA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 5 ASN A 242
ASP A 258
GLU A 142
SER A 240
 None
None
GAL  A4001 (-2.7A)
None
 1.44A 3p2kC-5ihrA:
undetectable		 3p2kC-5ihrA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 ILE A 230
SER A  64
ILE A  62
LEU A  53
ILE A 193
 None
 1.04A 3tq9A-5ihrA:
undetectable		 3tq9A-5ihrA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 SER A 240
GLY A 241
GLN A 288
 None
 0.65A 3v4tH-5ihrA:
undetectable		 3v4tH-5ihrA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 4 LEU A 396
ALA A 389
PHE A 332
ASN A  91
 None
 1.26A 3vaqA-5ihrA:
0.6		 3vaqA-5ihrA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 4 LEU A 396
ALA A 389
PHE A 332
ASN A  91
 None
 1.25A 3vasA-5ihrA:
0.6		 3vasA-5ihrA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 TYR A 362
GLY A 354
GLY A 358
TYR A 359
ALA A 100
 None
 1.06A 3vywC-5ihrA:
undetectable		 3vywC-5ihrA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PHE A 896
VAL A 927
ILE A 951
ASN A 928
 None
 1.13A 4a97E-5ihrA:
undetectable		 4a97E-5ihrA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 GLN A 997
ASN A 958
THR A 957
TRP A 959
 None
 1.14A 4d1yA-5ihrA:
undetectable
4d1yB-5ihrA:
undetectable		 4d1yA-5ihrA:
12.32
4d1yB-5ihrA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 LYS A 592
THR A 589
ILE A 186
 None
 0.91A 4e0fB-5ihrA:
undetectable		 4e0fB-5ihrA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 ARG A  71
HIS A  68
TYR A 362
 None
 1.28A 4fu8A-5ihrA:
undetectable		 4fu8A-5ihrA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 GLU A  66
HIS A  68
PRO A  69
VAL A  93
 None
 1.12A 4hvrA-5ihrA:
undetectable		 4hvrA-5ihrA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 ILE A 296
THR A 417
VAL A 429
ASP A 331
GLU A 490
 None
 1.41A 4i41A-5ihrA:
undetectable		 4i41A-5ihrA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 9 TYR A 486
VAL A 557
ILE A 555
GLU A 514
LEU A 505
 None
 1.35A 4l1xB-5ihrA:
9.0		 4l1xB-5ihrA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A 870
ALA A 961
PHE A 891
TYR A 859
 None
 1.05A 4lb2A-5ihrA:
undetectable		 4lb2A-5ihrA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 6 ASN A 320
GLU A 377
GLU A 381
GLU A 322
 MAN  A1627 (-3.7A)
MAN  A1625 (-2.8A)
None
MAN  A1626 (-3.7A)
 1.24A 4mi4A-5ihrA:
undetectable		 4mi4A-5ihrA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 ASN A 320
GLU A 377
GLU A 381
GLU A 322
 MAN  A1627 (-3.7A)
MAN  A1625 (-2.8A)
None
MAN  A1626 (-3.7A)
 1.23A 4mi4A-5ihrA:
undetectable
4mi4C-5ihrA:
undetectable		 4mi4A-5ihrA:
9.94
4mi4C-5ihrA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 ASN A 320
GLU A 377
GLU A 381
GLU A 322
 MAN  A1627 (-3.7A)
MAN  A1625 (-2.8A)
None
MAN  A1626 (-3.7A)
 1.26A 4mj8C-5ihrA:
undetectable		 4mj8C-5ihrA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 10 ASP A 720
LEU A 820
ILE A 819
TYR A 730
LEU A 836
 None
 1.08A 4odoA-5ihrA:
undetectable		 4odoA-5ihrA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 THR A 348
GLY A 346
HIS A  68
ASN A 349
SER A 944
 None
None
None
None
NAG  A1374 (-3.7A)
 1.36A 4pooB-5ihrA:
undetectable		 4pooB-5ihrA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 ASN A 320
GLU A 377
GLU A 381
GLU A 322
 MAN  A1627 (-3.7A)
MAN  A1625 (-2.8A)
None
MAN  A1626 (-3.7A)
 1.17A 4r87I-5ihrA:
undetectable		 4r87I-5ihrA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 TRP A  99
THR A 170
GLY A 145
LEU A 152
PRO A 149
 None
 1.45A 4uinH-5ihrA:
undetectable
4uinL-5ihrA:
undetectable		 4uinH-5ihrA:
12.43
4uinL-5ihrA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.40A 4v2yA-5ihrA:
undetectable		 4v2yA-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.46A 4v2yB-5ihrA:
undetectable		 4v2yB-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_C_EF2C151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.43A 4v2yC-5ihrA:
undetectable		 4v2yC-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.40A 4v2zA-5ihrA:
undetectable		 4v2zA-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.44A 4v2zB-5ihrA:
undetectable		 4v2zB-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.45A 4v2zC-5ihrA:
undetectable		 4v2zC-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 PRO A  69
PHE A 121
PHE A  70
TYR A 109
 None
 1.45A 4v2zC-5ihrA:
undetectable		 4v2zC-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.40A 4v30A-5ihrA:
undetectable		 4v30A-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.43A 4v30B-5ihrA:
undetectable		 4v30B-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 11 GLU A 949
LEU A 908
TYR A 981
LEU A 898
LEU A 669
 None
 1.10A 4wg0K-5ihrA:
undetectable
4wg0L-5ihrA:
undetectable
4wg0M-5ihrA:
undetectable		 4wg0K-5ihrA:
1.45
4wg0L-5ihrA:
1.45
4wg0M-5ihrA:
1.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 LEU A 503
LEU A 560
ILE A 562
LEU A 564
ILE A 555
 None
 0.74A 4y0rA-5ihrA:
undetectable		 4y0rA-5ihrA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 LEU A 853
GLY A 145
GLY A 146
ILE A 139
 None
 0.73A 4yjiA-5ihrA:
undetectable		 4yjiA-5ihrA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 SER A 751
SER A 361
MET A 343
GLU A 803
GLY A 801
 None
 1.41A 4zjlA-5ihrA:
undetectable		 4zjlA-5ihrA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.40A 5amhA-5ihrA:
undetectable		 5amhA-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.43A 5amiA-5ihrA:
undetectable		 5amiA-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.41A 5amiB-5ihrA:
undetectable		 5amiB-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.46A 5amjA-5ihrA:
undetectable		 5amjA-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.45A 5amjB-5ihrA:
undetectable		 5amjB-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.41A 5amkB-5ihrA:
undetectable		 5amkB-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 TYR A 506
ILE A 296
VAL A 430
GLY A 301
LEU A 382
 None
 1.10A 5esgA-5ihrA:
undetectable		 5esgA-5ihrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 8 HIS A 473
LEU A 447
LEU A 445
THR A 411
 None
 1.16A 5hs6A-5ihrA:
undetectable		 5hs6A-5ihrA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.79A 5jsdA-5ihrA:
undetectable		 5jsdA-5ihrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 TYR A  96
TYR A 260
GLN A 298
 GAL  A4001 (-4.8A)
GAL  A4001 ( 4.6A)
GAL  A4001 (-2.9A)
 1.13A 5jsdA-5ihrA:
undetectable
5jsdB-5ihrA:
undetectable		 5jsdA-5ihrA:
22.19
5jsdB-5ihrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 TYR A 260
TYR A  96
GLN A 298
 GAL  A4001 ( 4.6A)
GAL  A4001 (-4.8A)
GAL  A4001 (-2.9A)
 1.09A 5jsdA-5ihrA:
undetectable
5jsdB-5ihrA:
undetectable		 5jsdA-5ihrA:
22.19
5jsdB-5ihrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 TYR A  96
TYR A 260
GLN A 298
 GAL  A4001 (-4.8A)
GAL  A4001 ( 4.6A)
GAL  A4001 (-2.9A)
 1.14A 5jsdB-5ihrA:
undetectable
5jsdC-5ihrA:
undetectable		 5jsdB-5ihrA:
22.19
5jsdC-5ihrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 TYR A 260
TYR A  96
GLN A 298
 GAL  A4001 ( 4.6A)
GAL  A4001 (-4.8A)
GAL  A4001 (-2.9A)
 1.10A 5jsdB-5ihrA:
undetectable
5jsdC-5ihrA:
undetectable		 5jsdB-5ihrA:
22.19
5jsdC-5ihrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.80A 5jsdB-5ihrA:
undetectable		 5jsdB-5ihrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.79A 5jsdC-5ihrA:
undetectable		 5jsdC-5ihrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.79A 5jseA-5ihrA:
undetectable		 5jseA-5ihrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.78A 5jseB-5ihrA:
undetectable		 5jseB-5ihrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 THR A 488
SER A 487
TYR A 486
 None
 0.78A 5jseC-5ihrA:
undetectable		 5jseC-5ihrA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 6 VAL A 479
VAL A 474
SER A 487
ILE A 456
 None
 1.05A 5jw1B-5ihrA:
undetectable		 5jw1B-5ihrA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 ASP A 331
LEU A 194
LEU A  53
ALA A 337
ARG A 134
 None
 1.22A 5nd7B-5ihrA:
undetectable		 5nd7B-5ihrA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		3 / 3 LYS A 673
TRP A 677
SER A 671
 None
 1.19A 5nwwA-5ihrA:
undetectable		 5nwwA-5ihrA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.40A 5oh1A-5ihrA:
undetectable		 5oh1A-5ihrA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.42A 5oh1B-5ihrA:
undetectable		 5oh1B-5ihrA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.44A 5oh3A-5ihrA:
undetectable		 5oh3A-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 7 PRO A  69
PHE A  70
TRP A 350
TYR A 932
 None
 1.45A 5oh3B-5ihrA:
undetectable		 5oh3B-5ihrA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 11 VAL A 155
GLY A 157
SER A 162
ALA A 169
LEU A 152
 DMS  A3008 (-4.1A)
None
None
DMS  A3008 ( 4.1A)
None
 1.19A 5x6yC-5ihrA:
undetectable		 5x6yC-5ihrA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_2
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 4 ASP A 221
PRO A 197
GLU A 198
TYR A 166
 None
 1.18A 5xprA-5ihrA:
1.2		 5xprA-5ihrA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_A_TRPA501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 10 TYR A 215
TYR A 201
ASP A 212
VAL A 208
GLY A 809
 None
 1.07A 5zbdA-5ihrA:
undetectable		 5zbdA-5ihrA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_B_TRPB501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 10 TYR A 215
TYR A 201
ASP A 212
VAL A 208
GLY A 809
 None
 1.05A 5zbdB-5ihrA:
undetectable		 5zbdB-5ihrA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 ILE A 555
VAL A 525
SER A 535
VAL A 543
HIS A 512
 None
None
NAG  A1522 ( 4.6A)
None
None
 1.08A 6ap6A-5ihrA:
undetectable		 6ap6A-5ihrA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 ILE A 555
VAL A 525
SER A 535
VAL A 543
HIS A 512
 None
None
NAG  A1522 ( 4.6A)
None
None
 1.08A 6ap6B-5ihrA:
undetectable		 6ap6B-5ihrA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		4 / 6 GLU A 855
ARG A1003
VAL A 849
PRO A 998
 None
 1.40A 6fgdA-5ihrA:
undetectable		 6fgdA-5ihrA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 THR A 625
VAL A 627
VAL A 599
PHE A 621
ASN A 642
 DMS  A3001 (-3.8A)
None
None
None
None
 1.45A 6iblA-5ihrA:
undetectable		 6iblA-5ihrA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5ihr PROBABLE
BETA-GALACTOSIDASE A
(Aspergillus
niger) 		5 / 12 THR A 625
VAL A 627
VAL A 599
PHE A 621
ASN A 642
 DMS  A3001 (-3.8A)
None
None
None
None
 1.47A 6iblB-5ihrA:
undetectable		 6iblB-5ihrA:
17.86