SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ihs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  73
TRP A 303
None
1.24A 1c4dA-5ihsA:
undetectable
1c4dB-5ihsA:
undetectable
1c4dA-5ihsA:
4.71
1c4dB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 TRP A  78
VAL A  71
TRP A  73
None
1.08A 1c4dC-5ihsA:
undetectable
1c4dD-5ihsA:
undetectable
1c4dC-5ihsA:
4.71
1c4dD-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 PHE A 270
TRP A 267
GLU A 263
None
1.16A 1mogA-5ihsA:
undetectable
1mogA-5ihsA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 12 ASN A 158
GLU A 159
HIS A 219
GLU A 247
TRP A 281
None
0.45A 2v3dA-5ihsA:
7.1
2v3dA-5ihsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  73
TRP A  78
None
0.96A 2xdcA-5ihsA:
undetectable
2xdcB-5ihsA:
undetectable
2xdcA-5ihsA:
4.71
2xdcB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  78
TRP A  73
None
0.83A 2xdcA-5ihsA:
undetectable
2xdcB-5ihsA:
undetectable
2xdcA-5ihsA:
4.71
2xdcB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 TRP A  73
VAL A  71
TRP A  78
None
0.81A 2xdcA-5ihsA:
undetectable
2xdcB-5ihsA:
undetectable
2xdcA-5ihsA:
4.71
2xdcB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 TRP A  78
VAL A  71
TRP A  73
None
0.95A 2xdcA-5ihsA:
undetectable
2xdcB-5ihsA:
undetectable
2xdcA-5ihsA:
4.71
2xdcB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  73
TRP A  78
None
1.22A 2xdcC-5ihsA:
undetectable
2xdcD-5ihsA:
undetectable
2xdcC-5ihsA:
4.71
2xdcD-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  78
TRP A  73
None
0.87A 2xdcC-5ihsA:
undetectable
2xdcD-5ihsA:
undetectable
2xdcC-5ihsA:
4.71
2xdcD-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  73
TRP A  78
None
0.94A 2y5mA-5ihsA:
undetectable
2y5mB-5ihsA:
undetectable
2y5mA-5ihsA:
4.71
2y5mB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  78
TRP A  73
None
0.80A 2y5mA-5ihsA:
undetectable
2y5mB-5ihsA:
undetectable
2y5mA-5ihsA:
4.71
2y5mB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  73
TRP A  78
None
0.94A 2y6nA-5ihsA:
undetectable
2y6nB-5ihsA:
undetectable
2y6nA-5ihsA:
4.71
2y6nB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  78
TRP A  73
None
0.80A 2y6nA-5ihsA:
undetectable
2y6nB-5ihsA:
undetectable
2y6nA-5ihsA:
4.71
2y6nB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 TRP A  73
VAL A  71
TRP A  78
None
0.81A 2y6nA-5ihsA:
undetectable
2y6nB-5ihsA:
undetectable
2y6nA-5ihsA:
4.71
2y6nB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 TRP A  78
VAL A  71
TRP A  73
None
0.93A 2y6nA-5ihsA:
undetectable
2y6nB-5ihsA:
undetectable
2y6nA-5ihsA:
4.71
2y6nB-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 12 ARG A  84
GLU A 155
TYR A 221
ASN A 158
HIS A 124
None
1.47A 3bjmB-5ihsA:
undetectable
3bjmB-5ihsA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 12 SER A 165
THR A 164
ALA A 204
ILE A 209
LEU A 200
None
1.36A 3lcvB-5ihsA:
undetectable
3lcvB-5ihsA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 HIS A 124
PHE A 138
PHE A 139
None
0.57A 3lk0D-5ihsA:
undetectable
3lk0D-5ihsA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 12 ASP A 122
ILE A 121
ILE A  27
ILE A 152
TYR A 154
None
1.14A 3ohtA-5ihsA:
undetectable
3ohtB-5ihsA:
undetectable
3ohtA-5ihsA:
22.54
3ohtB-5ihsA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
4 / 5 VAL A 191
PHE A 139
ILE A 121
PHE A 138
None
1.12A 3owxB-5ihsA:
undetectable
3owxB-5ihsA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
4 / 6 VAL A 108
ASN A  67
TYR A  66
ILE A 283
None
1.16A 3q5sA-5ihsA:
undetectable
3q5sA-5ihsA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 12 ARG A  84
GLU A 155
TYR A 221
ASN A 158
HIS A 124
None
1.49A 3w2tA-5ihsA:
undetectable
3w2tA-5ihsA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 12 ARG A  84
GLU A 155
TYR A 221
ASN A 158
HIS A 124
None
1.44A 3w2tB-5ihsA:
undetectable
3w2tB-5ihsA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  73
TRP A  78
None
1.16A 3zq8A-5ihsA:
undetectable
3zq8B-5ihsA:
undetectable
3zq8A-5ihsA:
4.71
3zq8B-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 VAL A  71
TRP A  78
TRP A  73
None
0.82A 3zq8A-5ihsA:
undetectable
3zq8B-5ihsA:
undetectable
3zq8A-5ihsA:
4.71
3zq8B-5ihsA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
4 / 6 HIS A 219
GLU A 247
ASP A 122
SER A  55
None
1.01A 4apjA-5ihsA:
undetectable
4apjP-5ihsA:
undetectable
4apjA-5ihsA:
20.59
4apjP-5ihsA:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
4 / 5 ASN A 158
HIS A 124
GLU A 155
THR A 246
None
1.39A 4p6sA-5ihsA:
undetectable
4p6sA-5ihsA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
6 / 12 SER A  55
GLY A 193
SER A 198
GLU A 159
ASN A 158
ALA A 174
None
1.41A 4u95B-5ihsA:
undetectable
4u95B-5ihsA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
4 / 6 TYR A 268
GLY A 312
SER A 311
LEU A 314
None
1.01A 5bphA-5ihsA:
undetectable
5bphA-5ihsA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
4 / 7 TYR A 268
GLY A 312
SER A 311
LEU A 314
None
1.11A 5bphB-5ihsA:
undetectable
5bphB-5ihsA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
4 / 4 TYR A 268
GLY A 312
SER A 311
LEU A 314
None
0.98A 5bphC-5ihsA:
undetectable
5bphC-5ihsA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
4 / 6 TYR A 268
GLY A 312
SER A 311
LEU A 314
None
1.07A 5bphD-5ihsA:
undetectable
5bphD-5ihsA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 9 SER A  55
GLY A 193
SER A 198
GLU A 159
ALA A 174
None
1.42A 5entC-5ihsA:
undetectable
5entC-5ihsA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 12 MET A  91
ASP A 122
GLY A 193
THR A 217
TYR A 221
None
1.05A 5igiA-5ihsA:
undetectable
5igiA-5ihsA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 12 VAL A 156
GLU A 101
ALA A 134
ALA A 135
VAL A 177
None
1.07A 5igjA-5ihsA:
undetectable
5igjA-5ihsA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
4 / 8 ILE A 117
ILE A 152
GLU A 155
ALA A  85
None
0.76A 5og9A-5ihsA:
undetectable
5og9A-5ihsA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 THR A 246
GLU A 155
HIS A 124
None
0.87A 5xiqB-5ihsA:
undetectable
5xiqB-5ihsA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
3 / 3 THR A 246
GLU A 155
HIS A 124
None
0.89A 5xiqD-5ihsA:
undetectable
5xiqD-5ihsA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 12 ARG A  84
GLU A 155
TYR A 221
ASN A 158
HIS A 124
None
1.47A 6b1eB-5ihsA:
undetectable
6b1eB-5ihsA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii)
5 / 9 ALA A 292
GLY A 312
LEU A 314
GLY A 255
ASN A 280
None
1.19A 6nm4B-5ihsA:
undetectable
6nm4B-5ihsA:
20.23