SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ihu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
3 / 3 ALA H  33
VAL H  93
TRP H  36
None
0.70A 1gmkA-5ihuH:
undetectable
1gmkB-5ihuH:
undetectable
1gmkA-5ihuH:
5.56
1gmkB-5ihuH:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
3 / 3 ALA H  33
VAL H  93
TRP H  36
None
0.77A 1gmkC-5ihuH:
undetectable
1gmkD-5ihuH:
undetectable
1gmkC-5ihuH:
5.56
1gmkD-5ihuH:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
4 / 6 LYS H  13
LEU H  11
SER H  87
THR H  84
None
0.95A 1tyrA-5ihuH:
4.2
1tyrA-5ihuH:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
5 / 12 VAL H 218
VAL H 237
SER H 235
ASN H 251
ASN H 210
None
1.43A 2y03A-5ihuH:
undetectable
2y03A-5ihuH:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
5 / 12 VAL H 218
VAL H 237
SER H 235
ASN H 251
ASN H 210
None
1.46A 2y03B-5ihuH:
undetectable
2y03B-5ihuH:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
3 / 3 LYS H 263
LYS H 175
VAL H 176
None
1.05A 3brfA-5ihuH:
2.8
3brfA-5ihuH:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
5 / 12 VAL H 218
VAL H 237
SER H 235
ASN H 251
ASN H 210
None
1.43A 3nyaA-5ihuH:
undetectable
3nyaA-5ihuH:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
4 / 7 LYS H  13
LEU H  11
SER H  87
THR H  84
None
0.90A 3ozkB-5ihuH:
undetectable
3ozkB-5ihuH:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
4 / 6 LYS H  13
LEU H  11
SER H  87
THR H  84
None
0.88A 4ikiB-5ihuH:
undetectable
4ikiB-5ihuH:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
4 / 7 LYS H  13
LEU H  11
SER H  87
THR H  84
None
0.95A 4iklA-5ihuH:
undetectable
4iklB-5ihuH:
undetectable
4iklA-5ihuH:
19.55
4iklB-5ihuH:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
5 / 10 VAL H 218
VAL H 237
SER H 235
ASN H 251
ASN H 210
None
1.46A 4ldoA-5ihuH:
undetectable
4ldoA-5ihuH:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
5 / 11 VAL H 261
THR H 259
VAL H 265
ALA H 173
VAL H 207
None
1.06A 6dryA-5ihuH:
undetectable
6dryA-5ihuH:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)
5ihu BOVINE FAB B11 HEAVY
CHAIN

(Bos
taurus)
5 / 12 VAL H 218
VAL H 237
SER H 235
ASN H 251
ASN H 210
None
1.42A 6h7mB-5ihuH:
undetectable
6h7mB-5ihuH:
13.74