SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ihy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CLB_C_TMQC613_1 (DHFR-TS)	5ihy	UNCHARACTERIZED PROTEIN (Bacillus subtilis)	5 / 12	VAL A 81 ILE A 97 THR A 53 ILE A 50 ILE A 85	None	1.01A	3clbC-5ihyA: undetectable	3clbC-5ihyA: 18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BWL_C_MN9C1297_0 (N-ACETYLNEURAMINATE LYASE)	5ihy	UNCHARACTERIZED PROTEIN (Bacillus subtilis)	5 / 10	ILE A 200 LEU A 193 GLY A 150 GLY A 147 PHE A 138	None	1.08A	4bwlC-5ihyA: undetectable	4bwlC-5ihyA: 22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJJ_C_NCTC501_1 (CYTOCHROME P450 2A6)	5ihy	UNCHARACTERIZED PROTEIN (Bacillus subtilis)	4 / 5	PHE A 138 PHE A 159 ILE A 134 GLY A 133	None	1.02A	4ejjC-5ihyA: undetectable	4ejjC-5ihyA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_F_Z80F401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	5ihy	UNCHARACTERIZED PROTEIN (Bacillus subtilis)	5 / 10	ILE A 97 ILE A 94 VAL A 57 THR A 53 ASP A 89	None	1.13A	5lg3F-5ihyA: 2.0	5lg3F-5ihyA: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_G_Z80G401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	5ihy	UNCHARACTERIZED PROTEIN (Bacillus subtilis)	5 / 10	ILE A 97 ILE A 94 VAL A 57 THR A 53 ASP A 89	None	1.14A	5lg3G-5ihyA: undetectable	5lg3G-5ihyA: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_H_Z80H401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	5ihy	UNCHARACTERIZED PROTEIN (Bacillus subtilis)	5 / 10	ILE A 97 ILE A 94 VAL A 57 THR A 53 ASP A 89	None	1.12A	5lg3H-5ihyA: undetectable	5lg3H-5ihyA: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_I_Z80I401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	5ihy	UNCHARACTERIZED PROTEIN (Bacillus subtilis)	4 / 9	ILE A 94 VAL A 57 THR A 53 ASP A 89	None	1.06A	5lg3I-5ihyA: 3.2	5lg3I-5ihyA: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_J_Z80J401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	5ihy	UNCHARACTERIZED PROTEIN (Bacillus subtilis)	5 / 12	ILE A 97 ILE A 94 VAL A 57 THR A 53 ASP A 89	None	1.12A	5lg3J-5ihyA: undetectable	5lg3J-5ihyA: 19.55

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CLB_C_TMQC613_1","DHFR-TS","5ihy","UNCHARACTERIZED PROTEIN","Bacillus subtilis",5,"VAL A  81;ILE A  97;THR A  53;ILE A  50;ILE A  85","None","1.01A","3clbC-5ihyA:undetectable","3clbC-5ihyA:18.13"],["4BWL_C_MN9C1297_0","N-ACETYLNEURAMINATE LYASE","5ihy","UNCHARACTERIZED PROTEIN","Bacillus subtilis",5,"ILE A 200;LEU A 193;GLY A 150;GLY A 147;PHE A 138","None","1.08A","4bwlC-5ihyA:undetectable","4bwlC-5ihyA:22.29"],["4EJJ_C_NCTC501_1","CYTOCHROME P450 2A6","5ihy","UNCHARACTERIZED PROTEIN","Bacillus subtilis",4,"PHE A 138;PHE A 159;ILE A 134;GLY A 133","None","1.02A","4ejjC-5ihyA:undetectable","4ejjC-5ihyA:19.75"],["5LG3_F_Z80F401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","5ihy","UNCHARACTERIZED PROTEIN","Bacillus subtilis",5,"ILE A  97;ILE A  94;VAL A  57;THR A  53;ASP A  89","None","1.13A","5lg3F-5ihyA:2.0","5lg3F-5ihyA:19.55"],["5LG3_G_Z80G401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","5ihy","UNCHARACTERIZED PROTEIN","Bacillus subtilis",5,"ILE A  97;ILE A  94;VAL A  57;THR A  53;ASP A  89","None","1.14A","5lg3G-5ihyA:undetectable","5lg3G-5ihyA:19.55"],["5LG3_H_Z80H401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","5ihy","UNCHARACTERIZED PROTEIN","Bacillus subtilis",5,"ILE A  97;ILE A  94;VAL A  57;THR A  53;ASP A  89","None","1.12A","5lg3H-5ihyA:undetectable","5lg3H-5ihyA:19.55"],["5LG3_I_Z80I401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","5ihy","UNCHARACTERIZED PROTEIN","Bacillus subtilis",4,"ILE A  94;VAL A  57;THR A  53;ASP A  89","None","1.06A","5lg3I-5ihyA:3.2","5lg3I-5ihyA:19.55"],["5LG3_J_Z80J401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","5ihy","UNCHARACTERIZED PROTEIN","Bacillus subtilis",5,"ILE A  97;ILE A  94;VAL A  57;THR A  53;ASP A  89","None","1.12A","5lg3J-5ihyA:undetectable","5lg3J-5ihyA:19.55"]]