SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ii5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 6 VAL A3675
VAL A3717
ILE A3727
ASN A3934
None
0.94A 1e06A-5ii5A:
undetectable
1e06A-5ii5A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 9 ILE A3676
LEU A3929
VAL A3960
GLY A3683
LEU A3951
None
1.25A 1e7aB-5ii5A:
0.5
1e7aB-5ii5A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
3 / 3 GLU A3778
TRP A3897
LYS A3940
MAL  A4201 (-3.0A)
MAL  A4201 ( 3.3A)
None
1.24A 1qu2A-5ii5A:
undetectable
1qu2A-5ii5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 11 THR A3760
GLN A3992
ALA A3991
ALA A3970
ALA A3968
None
PGE  A4204 (-4.6A)
PGE  A4204 (-3.2A)
None
None
1.15A 2f16H-5ii5A:
undetectable
2f16I-5ii5A:
undetectable
2f16H-5ii5A:
20.28
2f16I-5ii5A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 11 THR A3760
GLN A3992
ALA A3991
ALA A3970
ALA A3968
None
PGE  A4204 (-4.6A)
PGE  A4204 (-3.2A)
None
None
1.13A 2f16V-5ii5A:
undetectable
2f16W-5ii5A:
undetectable
2f16V-5ii5A:
20.28
2f16W-5ii5A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 6 VAL A4143
PHE A4106
PRO A4093
THR A4095
None
1.17A 2q6oB-5ii5A:
undetectable
2q6oB-5ii5A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 7 ASP A4038
ARG A4081
VAL A4064
ILE A3845
None
1.03A 2yfbA-5ii5A:
undetectable
2yfbA-5ii5A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 6 ASP A4038
ARG A4081
VAL A4064
ILE A3845
None
1.07A 2yfbB-5ii5A:
undetectable
2yfbB-5ii5A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 12 ILE A3775
LEU A3929
ILE A3726
VAL A3690
LEU A3687
None
1.05A 3a51C-5ii5A:
undetectable
3a51C-5ii5A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 6 PHE A3925
ALA A3829
LEU A3914
PRO A3826
None
0.95A 3bgdA-5ii5A:
undetectable
3bgdA-5ii5A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 7 VAL A3777
GLY A3967
PRO A3896
LYS A3972
None
0.76A 3bjwC-5ii5A:
undetectable
3bjwC-5ii5A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 8 VAL A3777
GLY A3967
PRO A3896
LYS A3972
None
0.95A 3bjwA-5ii5A:
undetectable
3bjwA-5ii5A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
3 / 3 LYS A4066
LYS A4061
VAL A4064
None
0.79A 3brfA-5ii5A:
undetectable
3brfA-5ii5A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 6 PRO A3793
LEU A3814
ALA A3890
PRO A3792
None
1.27A 3gv1A-5ii5A:
undetectable
3gv1C-5ii5A:
undetectable
3gv1A-5ii5A:
13.77
3gv1C-5ii5A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 6 LEU A3814
ALA A3890
PRO A3792
PRO A3793
None
1.26A 3gv1A-5ii5A:
undetectable
3gv1B-5ii5A:
undetectable
3gv1A-5ii5A:
13.77
3gv1B-5ii5A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 12 VAL A4010
GLY A3854
ALA A3855
LEU A3859
LEU A3827
None
1.05A 3hs6A-5ii5A:
undetectable
3hs6A-5ii5A:
20.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
10 / 12 ASP A3681
LYS A3682
LYS A3709
GLU A3711
GLU A3712
ALA A3730
ASP A3732
ARG A3733
GLU A3778
TRP A3897
MAL  A4201 (-2.6A)
MAL  A4201 (-2.3A)
None
None
None
MAL  A4201 (-3.2A)
MAL  A4201 (-2.5A)
MAL  A4201 (-3.8A)
MAL  A4201 (-3.0A)
MAL  A4201 ( 3.3A)
0.65A 3jyrA-5ii5A:
37.7
3jyrA-5ii5A:
68.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
10 / 12 ASP A3681
LYS A3682
LYS A3709
GLU A3711
GLU A3712
ALA A3730
ASP A3732
GLU A3778
PRO A3821
TRP A3897
MAL  A4201 (-2.6A)
MAL  A4201 (-2.3A)
None
None
None
MAL  A4201 (-3.2A)
MAL  A4201 (-2.5A)
MAL  A4201 (-3.0A)
MAL  A4201 (-3.0A)
MAL  A4201 ( 3.3A)
0.46A 3jyrA-5ii5A:
37.7
3jyrA-5ii5A:
68.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
6 / 7 ASN A3679
TRP A3729
GLU A3820
TYR A3822
MET A3997
TRP A4007
MAL  A4201 (-4.6A)
MAL  A4201 (-3.7A)
MAL  A4201 (-3.2A)
MAL  A4201 (-2.8A)
MAL  A4201 ( 3.5A)
MAL  A4201 (-2.6A)
0.20A 3jyrA-5ii5A:
37.7
3jyrA-5ii5A:
68.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 11 THR A3760
GLN A3992
ALA A3991
ALA A3970
ALA A3968
None
PGE  A4204 (-4.6A)
PGE  A4204 (-3.2A)
None
None
1.17A 3mg0V-5ii5A:
undetectable
3mg0W-5ii5A:
undetectable
3mg0V-5ii5A:
20.28
3mg0W-5ii5A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 12 VAL A3863
LEU A3827
GLY A3854
ALA A3855
LEU A4028
PGE  A4205 ( 4.7A)
None
None
None
None
1.01A 3n8yB-5ii5A:
undetectable
3n8yB-5ii5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 9 ILE A3828
GLN A4032
ALA A4029
LEU A4028
ALA A3829
None
1.08A 3ozvB-5ii5A:
undetectable
3ozvB-5ii5A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 12 PHE A3823
GLY A3967
LEU A3966
GLU A3778
ALA A3898
MAL  A4201 ( 4.2A)
None
None
MAL  A4201 (-3.0A)
None
0.84A 3tbgB-5ii5A:
undetectable
3tbgB-5ii5A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 12 PHE A3823
GLY A3967
LEU A3966
GLU A3778
ALA A3898
MAL  A4201 ( 4.2A)
None
None
MAL  A4201 (-3.0A)
None
0.82A 3tbgD-5ii5A:
undetectable
3tbgD-5ii5A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 12 ALA A3898
TYR A3684
TYR A3877
ASN A3901
GLY A3895
None
1.39A 3vwqA-5ii5A:
undetectable
3vwqA-5ii5A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWR_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 11 ALA A3898
ASP A3963
TYR A3877
ASN A3901
GLY A3895
None
1.28A 3vwrA-5ii5A:
undetectable
3vwrA-5ii5A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 8 PHE A4106
VAL A4123
MET A4077
ILE A4070
None
0.79A 4a97C-5ii5A:
undetectable
4a97C-5ii5A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 8 PHE A4106
VAL A4123
MET A4077
ILE A4070
None
0.80A 4a97D-5ii5A:
undetectable
4a97D-5ii5A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 8 PHE A4106
VAL A4123
MET A4077
ILE A4070
None
0.81A 4a97G-5ii5A:
undetectable
4a97G-5ii5A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 8 PHE A4106
VAL A4123
MET A4077
ILE A4070
None
0.86A 4a97I-5ii5A:
3.0
4a97I-5ii5A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 5 ASN A3934
ALA A3718
GLY A3723
ASP A3681
None
None
None
MAL  A4201 (-2.6A)
0.96A 4n48A-5ii5A:
undetectable
4n48A-5ii5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB602_1
(SERUM ALBUMIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 9 ALA A3931
ALA A3772
LEU A3770
LEU A3929
VAL A3928
None
1.17A 4or0B-5ii5A:
undetectable
4or0B-5ii5A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 4 ASN A4034
SER A4004
ALA A4009
VAL A4010
None
1.39A 4x1kC-5ii5A:
undetectable
4x1kC-5ii5A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
4 / 4 ASN A4034
SER A4004
ALA A4009
VAL A4010
None
1.39A 5nm5A-5ii5A:
undetectable
5nm5A-5ii5A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
6 / 12 ALA A4009
ALA A4005
GLY A3833
ALA A3855
PHE A3836
VAL A3848
None
1.43A 5w4zA-5ii5A:
undetectable
5w4zA-5ii5A:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
6 / 12 ALA A4009
ALA A4005
GLY A3833
ALA A3855
PHE A3836
VAL A3848
None
1.45A 5w4zB-5ii5A:
undetectable
5w4zB-5ii5A:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 12 LEU A3806
LEU A3789
ASN A3791
ILE A3799
LYS A3794
None
1.32A 5xiwD-5ii5A:
undetectable
5xiwD-5ii5A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 12 LEU A3806
LEU A3789
THR A3912
ILE A3799
LYS A3794
None
1.20A 5xiwD-5ii5A:
undetectable
5xiwD-5ii5A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
3 / 3 TYR A3822
ASN A3894
LEU A3780
MAL  A4201 (-2.8A)
None
None
0.81A 6b58A-5ii5A:
undetectable
6b58A-5ii5A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
5 / 11 PRO A3800
GLU A3797
PRO A3921
ALA A3830
PRO A3826
None
1.41A 6bm5A-5ii5A:
undetectable
6bm5A-5ii5A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens)
3 / 3 PHE A4060
ARG A4081
ALA A4005
None
0.89A 6ecfB-5ii5A:
undetectable
6ecfB-5ii5A:
21.40