SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ijb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XF1_B_ACTB1108_0 (C5A PEPTIDASE)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 6	LEU A 356 ASN A 407 ILE A 363 PHE A 365	None	0.85A	1xf1B-5ijbA: undetectable	1xf1B-5ijbA: 20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA501_1 (CYTOCHROME P450 2B4)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 7	LEU A 232 GLY A 260 THR A 292 ILE A 299	None	1.04A	2bdmA-5ijbA: undetectable	2bdmA-5ijbA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HC4_A_VDXA525_1 (VITAMIN D RECEPTOR)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	PHE A 121 LEU A 130 VAL A 131 VAL A 179 HIS A 178	None	1.36A	2hc4A-5ijbA: undetectable	2hc4A-5ijbA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2I2Z_A_SALA1100_1 (SERUM ALBUMIN)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 5	LEU A 106 LEU A 68 ILE A 92 ILE A 113	None	0.75A	2i2zA-5ijbA: undetectable	2i2zA-5ijbA: 19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J7X_A_ESTA1454_1 (ESTROGEN RECEPTOR BETA)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	LEU A 207 LEU A 194 LEU A 197 GLY A 251 LEU A 249	None	1.01A	2j7xA-5ijbA: undetectable	2j7xA-5ijbA: 19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_A_P1ZA1351_1 (PROSTAGLANDIN REDUCTASE 2)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 10	ILE A 92 PHE A 143 LEU A 106 VAL A 131 LEU A 130	None	1.37A	2w98A-5ijbA: undetectable	2w98A-5ijbA: 18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y69_C_CHDC1265_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 5	ARG A 198 PHE A 170 LEU A 194 PHE A 222	None	1.37A	2y69C-5ijbA: undetectable 2y69J-5ijbA: undetectable	2y69C-5ijbA: 16.33 2y69J-5ijbA: 7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 5	ARG A 198 PHE A 170 LEU A 194 PHE A 222	None	1.29A	3ablC-5ijbA: undetectable 3ablJ-5ijbA: undetectable	3ablC-5ijbA: 16.33 3ablJ-5ijbA: 6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 5	ARG A 198 PHE A 170 LEU A 194 PHE A 222	None	1.38A	3abmC-5ijbA: undetectable 3abmJ-5ijbA: undetectable	3abmC-5ijbA: 16.33 3abmJ-5ijbA: 6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 4	ARG A 198 PHE A 170 LEU A 194 PHE A 222	None	1.29A	3ag1P-5ijbA: undetectable 3ag1W-5ijbA: 0.0	3ag1P-5ijbA: 16.33 3ag1W-5ijbA: 6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_K_SAMK302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	LEU A 252 ILE A 189 ASP A 193 LEU A 227 LEU A 230	None	1.28A	3cjtK-5ijbA: undetectable	3cjtK-5ijbA: 17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H5G_C_LEIC16_0 (COIL SER L16D-PEN)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 6	LEU A 522 GLN A 600 LEU A 547 GLU A 546	None	1.11A	3h5gB-5ijbA: undetectable 3h5gC-5ijbA: undetectable	3h5gB-5ijbA: 4.16 3h5gC-5ijbA: 4.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IK6_B_HCZB262_1 (GLUTAMATE RECEPTOR 2)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 10	ILE A 145 PRO A 144 SER A 142 SER A 115 LEU A 130	None	1.30A	3ik6B-5ijbA: undetectable 3ik6E-5ijbA: undetectable	3ik6B-5ijbA: 18.29 3ik6E-5ijbA: 18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OLS_A_ESTA600_1 (ESTROGEN RECEPTOR BETA)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	LEU A 207 LEU A 194 LEU A 197 GLY A 251 LEU A 249	None	1.01A	3olsA-5ijbA: undetectable	3olsA-5ijbA: 17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OZU_A_X89A411_1 (FLAVOHEMOPROTEIN)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	ILE A 113 ALA A 132 LEU A 108 LEU A 68 LEU A 100	None	1.21A	3ozuA-5ijbA: undetectable	3ozuA-5ijbA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP6_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	PHE A 441 THR A 493 ILE A 452 MET A 476 VAL A 435	None	1.46A	3sp6A-5ijbA: undetectable	3sp6A-5ijbA: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_A_9PLA501_1 (CYTOCHROME P450 2E1)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 6	PHE A 427 LEU A 422 ALA A 440 LEU A 450	None	0.92A	3t3zA-5ijbA: undetectable	3t3zA-5ijbA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_B_9PLB501_1 (CYTOCHROME P450 2E1)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 6	PHE A 427 LEU A 422 ALA A 440 LEU A 450	None	0.92A	3t3zB-5ijbA: undetectable	3t3zB-5ijbA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_C_9PLC501_1 (CYTOCHROME P450 2E1)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 5	PHE A 490 PHE A 481 THR A 457 LEU A 474	None	1.20A	3t3zC-5ijbA: undetectable	3t3zC-5ijbA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_D_9PLD501_1 (CYTOCHROME P450 2E1)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 6	PHE A 427 LEU A 422 ALA A 440 LEU A 450	None	0.90A	3t3zD-5ijbA: undetectable	3t3zD-5ijbA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U7S_A_017A202_1 (POL POLYPROTEIN)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 9	LEU A 496 ALA A 491 GLY A 463 ILE A 464 LEU A 471	None	1.09A	3u7sA-5ijbA: undetectable	3u7sA-5ijbA: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJJ_B_NCTB501_1 (CYTOCHROME P450 2A6)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 7	PHE A 121 PHE A 116 THR A 135 PHE A 143	None	0.93A	4ejjB-5ijbA: undetectable	4ejjB-5ijbA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7U_D_YTZD802_1 (SEPIAPTERIN REDUCTASE)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 8	SER A 85 LEU A 84 TRP A 81 GLN A 38	None	1.07A	4j7uD-5ijbA: undetectable	4j7uD-5ijbA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MDA_A_RLTA403_1 (MARINER MOS1 TRANSPOSASE)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 6	ASP A 377 ASN A 359 ALA A 382 ASP A 403	None	1.08A	4mdaA-5ijbA: undetectable	4mdaA-5ijbA: 16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_G_IPHG101_0 (INSULIN)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 11	VAL A 557 LEU A 554 LEU A 592 LEU A 573 ALA A 603	None	1.13A	4p65B-5ijbA: undetectable 4p65D-5ijbA: undetectable 4p65G-5ijbA: undetectable 4p65H-5ijbA: undetectable	4p65B-5ijbA: 4.12 4p65D-5ijbA: 4.12 4p65G-5ijbA: 3.84 4p65H-5ijbA: 4.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_K_IPHK101_0 (INSULIN)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	VAL A 557 LEU A 554 LEU A 592 LEU A 573 ALA A 603	None	1.04A	4p65F-5ijbA: undetectable 4p65H-5ijbA: undetectable 4p65K-5ijbA: undetectable 4p65L-5ijbA: undetectable	4p65F-5ijbA: 4.12 4p65H-5ijbA: 4.12 4p65K-5ijbA: 3.84 4p65L-5ijbA: 4.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUM_A_IMNA501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	PHE A 514 ILE A 464 LEU A 501 LEU A 499 LEU A 474	None	1.22A	4xumA-5ijbA: undetectable	4xumA-5ijbA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE0_A_VORA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 9	THR A 457 ILE A 452 GLY A 478 LEU A 506 LEU A 486	None	1.34A	4ze0A-5ijbA: undetectable	4ze0A-5ijbA: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXG_B_ESTB601_1 (ESTROGEN RECEPTOR)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 11	LEU A 207 LEU A 194 LEU A 197 GLY A 251 LEU A 249	None	0.97A	5dxgB-5ijbA: undetectable	5dxgB-5ijbA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GTR_A_ESTA601_1 (ESTROGEN RECEPTOR)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	LEU A 207 LEU A 194 LEU A 197 GLY A 251 LEU A 249	None	0.94A	5gtrA-5ijbA: undetectable	5gtrA-5ijbA: 20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNW_B_TA1B902_1 (TUBULIN BETA-2B CHAIN)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	GLU A 141 LEU A 227 LEU A 197 PHE A 170 LEU A 205	None	1.20A	5hnwB-5ijbA: undetectable	5hnwB-5ijbA: 21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNY_B_TA1B601_1 (TUBULIN BETA-2B CHAIN)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	5 / 12	GLU A 141 LEU A 227 LEU A 197 PHE A 170 LEU A 205	None	1.21A	5hnyB-5ijbA: undetectable	5hnyB-5ijbA: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_A_CELA602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 6	LEU A 232 SER A 210 ILE A 214 PHE A 236	None	0.98A	5jw1A-5ijbA: undetectable	5jw1A-5ijbA: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUN_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 8	SER A 480 ASN A 484 PHE A 481 ASP A 460	None	1.32A	5vunB-5ijbA: undetectable	5vunB-5ijbA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 5	ARG A 198 PHE A 170 LEU A 194 PHE A 222	None	1.28A	5wauC-5ijbA: undetectable 5wauJ-5ijbA: undetectable	5wauC-5ijbA: 16.33 5wauJ-5ijbA: 6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_C_CHDC308_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 5	ARG A 198 PHE A 170 LEU A 194 PHE A 222	None	1.27A	5wauc-5ijbA: undetectable 5wauj-5ijbA: undetectable	5wauc-5ijbA: 16.33 5wauj-5ijbA: 6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_A_SAMA902_1 (MRNA CAPPING ENZYME P5)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	3 / 3	TYR A 449 ASP A 403 ASP A 451	None	0.58A	5x6yA-5ijbA: undetectable	5x6yA-5ijbA: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCO_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5ijb	TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA (Eptatretus burgeri; Mus musculus)	4 / 8	ILE A 318 ARG A 337 THR A 357 LEU A 356	None	0.89A	5zcoA-5ijbA: undetectable 5zcoJ-5ijbA: undetectable	5zcoA-5ijbA: 23.10 5zcoJ-5ijbA: 6.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XF1_B_ACTB1108_0","C5A PEPTIDASE","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"LEU A 356;ASN A 407;ILE A 363;PHE A 365","None","0.85A","1xf1B-5ijbA:undetectable","1xf1B-5ijbA:20.55"],["2BDM_A_TMIA501_1","CYTOCHROME P450 2B4","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"LEU A 232;GLY A 260;THR A 292;ILE A 299","None","1.04A","2bdmA-5ijbA:undetectable","2bdmA-5ijbA:21.27"],["2HC4_A_VDXA525_1","VITAMIN D RECEPTOR","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"PHE A 121;LEU A 130;VAL A 131;VAL A 179;HIS A 178","None","1.36A","2hc4A-5ijbA:undetectable","2hc4A-5ijbA:19.70"],["2I2Z_A_SALA1100_1","SERUM ALBUMIN","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"LEU A 106;LEU A  68;ILE A  92;ILE A 113","None","0.75A","2i2zA-5ijbA:undetectable","2i2zA-5ijbA:19.94"],["2J7X_A_ESTA1454_1","ESTROGEN RECEPTOR BETA","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"LEU A 207;LEU A 194;LEU A 197;GLY A 251;LEU A 249","None","1.01A","2j7xA-5ijbA:undetectable","2j7xA-5ijbA:19.31"],["2W98_A_P1ZA1351_1","PROSTAGLANDIN REDUCTASE 2","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"ILE A  92;PHE A 143;LEU A 106;VAL A 131;LEU A 130","None","1.37A","2w98A-5ijbA:undetectable","2w98A-5ijbA:18.95"],["2Y69_C_CHDC1265_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"ARG A 198;PHE A 170;LEU A 194;PHE A 222","None","1.37A","2y69C-5ijbA:undetectable;2y69J-5ijbA:undetectable","2y69C-5ijbA:16.33;2y69J-5ijbA:7.85"],["3ABL_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"ARG A 198;PHE A 170;LEU A 194;PHE A 222","None","1.29A","3ablC-5ijbA:undetectable;3ablJ-5ijbA:undetectable","3ablC-5ijbA:16.33;3ablJ-5ijbA:6.91"],["3ABM_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"ARG A 198;PHE A 170;LEU A 194;PHE A 222","None","1.38A","3abmC-5ijbA:undetectable;3abmJ-5ijbA:undetectable","3abmC-5ijbA:16.33;3abmJ-5ijbA:6.91"],["3AG1_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"ARG A 198;PHE A 170;LEU A 194;PHE A 222","None","1.29A","3ag1P-5ijbA:undetectable;3ag1W-5ijbA:0.0","3ag1P-5ijbA:16.33;3ag1W-5ijbA:6.91"],["3CJT_K_SAMK302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"LEU A 252;ILE A 189;ASP A 193;LEU A 227;LEU A 230","None","1.28A","3cjtK-5ijbA:undetectable","3cjtK-5ijbA:17.54"],["3H5G_C_LEIC16_0","COIL SER L16D-PEN","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"LEU A 522;GLN A 600;LEU A 547;GLU A 546","None","1.11A","3h5gB-5ijbA:undetectable;3h5gC-5ijbA:undetectable","3h5gB-5ijbA:4.16;3h5gC-5ijbA:4.16"],["3IK6_B_HCZB262_1","GLUTAMATE RECEPTOR 2;GLUTAMATE RECEPTOR 2","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"ILE A 145;PRO A 144;SER A 142;SER A 115;LEU A 130","None","1.30A","3ik6B-5ijbA:undetectable;3ik6E-5ijbA:undetectable","3ik6B-5ijbA:18.29;3ik6E-5ijbA:18.29"],["3OLS_A_ESTA600_1","ESTROGEN RECEPTOR BETA","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"LEU A 207;LEU A 194;LEU A 197;GLY A 251;LEU A 249","None","1.01A","3olsA-5ijbA:undetectable","3olsA-5ijbA:17.94"],["3OZU_A_X89A411_1","FLAVOHEMOPROTEIN","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"ILE A 113;ALA A 132;LEU A 108;LEU A  68;LEU A 100","None","1.21A","3ozuA-5ijbA:undetectable","3ozuA-5ijbA:21.35"],["3SP6_A_IL2A901_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"PHE A 441;THR A 493;ILE A 452;MET A 476;VAL A 435","None","1.46A","3sp6A-5ijbA:undetectable","3sp6A-5ijbA:20.64"],["3T3Z_A_9PLA501_1","CYTOCHROME P450 2E1","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"PHE A 427;LEU A 422;ALA A 440;LEU A 450","None","0.92A","3t3zA-5ijbA:undetectable","3t3zA-5ijbA:22.50"],["3T3Z_B_9PLB501_1","CYTOCHROME P450 2E1","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"PHE A 427;LEU A 422;ALA A 440;LEU A 450","None","0.92A","3t3zB-5ijbA:undetectable","3t3zB-5ijbA:22.50"],["3T3Z_C_9PLC501_1","CYTOCHROME P450 2E1","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"PHE A 490;PHE A 481;THR A 457;LEU A 474","None","1.20A","3t3zC-5ijbA:undetectable","3t3zC-5ijbA:22.50"],["3T3Z_D_9PLD501_1","CYTOCHROME P450 2E1","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"PHE A 427;LEU A 422;ALA A 440;LEU A 450","None","0.90A","3t3zD-5ijbA:undetectable","3t3zD-5ijbA:22.50"],["3U7S_A_017A202_1","POL POLYPROTEIN","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"LEU A 496;ALA A 491;GLY A 463;ILE A 464;LEU A 471","None","1.09A","3u7sA-5ijbA:undetectable","3u7sA-5ijbA:10.80"],["4EJJ_B_NCTB501_1","CYTOCHROME P450 2A6","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"PHE A 121;PHE A 116;THR A 135;PHE A 143","None","0.93A","4ejjB-5ijbA:undetectable","4ejjB-5ijbA:21.13"],["4J7U_D_YTZD802_1","SEPIAPTERIN REDUCTASE","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"SER A  85;LEU A  84;TRP A  81;GLN A  38","None","1.07A","4j7uD-5ijbA:undetectable","4j7uD-5ijbA:20.40"],["4MDA_A_RLTA403_1","MARINER MOS1 TRANSPOSASE","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"ASP A 377;ASN A 359;ALA A 382;ASP A 403","None","1.08A","4mdaA-5ijbA:undetectable","4mdaA-5ijbA:16.41"],["4P65_G_IPHG101_0","INSULIN","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"VAL A 557;LEU A 554;LEU A 592;LEU A 573;ALA A 603","None","1.13A","4p65B-5ijbA:undetectable;4p65D-5ijbA:undetectable;4p65G-5ijbA:undetectable;4p65H-5ijbA:undetectable","4p65B-5ijbA:4.12;4p65D-5ijbA:4.12;4p65G-5ijbA:3.84;4p65H-5ijbA:4.12"],["4P65_K_IPHK101_0","INSULIN","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"VAL A 557;LEU A 554;LEU A 592;LEU A 573;ALA A 603","None","1.04A","4p65F-5ijbA:undetectable;4p65H-5ijbA:undetectable;4p65K-5ijbA:undetectable;4p65L-5ijbA:undetectable","4p65F-5ijbA:4.12;4p65H-5ijbA:4.12;4p65K-5ijbA:3.84;4p65L-5ijbA:4.12"],["4XUM_A_IMNA501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"PHE A 514;ILE A 464;LEU A 501;LEU A 499;LEU A 474","None","1.22A","4xumA-5ijbA:undetectable","4xumA-5ijbA:20.20"],["4ZE0_A_VORA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"THR A 457;ILE A 452;GLY A 478;LEU A 506;LEU A 486","None","1.34A","4ze0A-5ijbA:undetectable","4ze0A-5ijbA:21.19"],["5DXG_B_ESTB601_1","ESTROGEN RECEPTOR","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"LEU A 207;LEU A 194;LEU A 197;GLY A 251;LEU A 249","None","0.97A","5dxgB-5ijbA:undetectable","5dxgB-5ijbA:20.75"],["5GTR_A_ESTA601_1","ESTROGEN RECEPTOR","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"LEU A 207;LEU A 194;LEU A 197;GLY A 251;LEU A 249","None","0.94A","5gtrA-5ijbA:undetectable","5gtrA-5ijbA:20.55"],["5HNW_B_TA1B902_1","TUBULIN BETA-2B CHAIN","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"GLU A 141;LEU A 227;LEU A 197;PHE A 170;LEU A 205","None","1.20A","5hnwB-5ijbA:undetectable","5hnwB-5ijbA:21.67"],["5HNY_B_TA1B601_1","TUBULIN BETA-2B CHAIN","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",5,"GLU A 141;LEU A 227;LEU A 197;PHE A 170;LEU A 205","None","1.21A","5hnyB-5ijbA:undetectable","5hnyB-5ijbA:21.50"],["5JW1_A_CELA602_2","PROSTAGLANDIN G\/H SYNTHASE 2","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"LEU A 232;SER A 210;ILE A 214;PHE A 236","None","0.98A","5jw1A-5ijbA:undetectable","5jw1A-5ijbA:22.37"],["5VUN_B_MTLB805_0","NITRIC OXIDE SYNTHASE, BRAIN","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"SER A 480;ASN A 484;PHE A 481;ASP A 460","None","1.32A","5vunB-5ijbA:undetectable","5vunB-5ijbA:20.20"],["5WAU_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"ARG A 198;PHE A 170;LEU A 194;PHE A 222","None","1.28A","5wauC-5ijbA:undetectable;5wauJ-5ijbA:undetectable","5wauC-5ijbA:16.33;5wauJ-5ijbA:6.91"],["5WAU_C_CHDC308_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"ARG A 198;PHE A 170;LEU A 194;PHE A 222","None","1.27A","5wauc-5ijbA:undetectable;5wauj-5ijbA:undetectable","5wauc-5ijbA:16.33;5wauj-5ijbA:6.91"],["5X6Y_A_SAMA902_1","MRNA CAPPING ENZYME P5","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",3,"TYR A 449;ASP A 403;ASP A 451","None","0.58A","5x6yA-5ijbA:undetectable","5x6yA-5ijbA:22.56"],["5ZCO_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5ijb","TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA","Eptatretus burgeri;Mus musculus",4,"ILE A 318;ARG A 337;THR A 357;LEU A 356","None","0.89A","5zcoA-5ijbA:undetectable;5zcoJ-5ijbA:undetectable","5zcoA-5ijbA:23.10;5zcoJ-5ijbA:6.91"]]