SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ijj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_B_CTXB2_1 (CES1 PROTEIN)	5ijj	SPX DOMAIN (Chaetomium thermophilum)	5 / 12	VAL A 159 SER A 107 LEU A 112 LEU A 76 LEU A 163	None	1.26A	1ya4B-5ijjA: undetectable	1ya4B-5ijjA: 15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA502_1 (CYTOCHROME P450 2B4)	5ijj	SPX DOMAIN (Chaetomium thermophilum)	5 / 12	LEU A 105 LEU A 102 ILE A 166 ILE A 162 THR A 82	None	1.04A	2bdmA-5ijjA: undetectable	2bdmA-5ijjA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q63_A_1UNA1001_2 (PROTEASE RETROPEPSIN)	5ijj	SPX DOMAIN (Chaetomium thermophilum)	3 / 3	ARG A 142 ASN A 54 THR A 127	ACT A 503 (-3.9A) EDO A 501 (-3.2A) None	0.86A	2q63A-5ijjA: undetectable	2q63A-5ijjA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VL2_B_BEZB1162_0 (PEROXIREDOXIN-5)	5ijj	SPX DOMAIN (Chaetomium thermophilum)	4 / 7	THR A 127 LEU A 44 PHE A 48 THR A 137	None None ACT A 503 ( 3.7A) None	1.04A	2vl2B-5ijjA: undetectable	2vl2B-5ijjA: 22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVR_B_URFB2011_1 (URIDINE PHOSPHORYLASE)	5ijj	SPX DOMAIN (Chaetomium thermophilum)	5 / 10	GLY A 100 GLU A 97 LEU A 102 LEU A 103 ILE A 170	None	1.27A	3kvrB-5ijjA: undetectable	3kvrB-5ijjA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NBQ_A_URFA400_1 (URIDINE PHOSPHORYLASE 1)	5ijj	SPX DOMAIN (Chaetomium thermophilum)	5 / 9	GLY A 100 GLU A 97 LEU A 102 LEU A 103 ILE A 170	None	1.38A	3nbqA-5ijjA: undetectable	3nbqA-5ijjA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FA8_A_SAMA301_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE)	5ijj	SPX DOMAIN (Chaetomium thermophilum)	5 / 12	GLY A 116 ILE A 118 ARG A 120 PHE A 115 LEU A 55	None	1.14A	5fa8A-5ijjA: undetectable	5fa8A-5ijjA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_0 (CYTOCHROME P450 1A1)	5ijj	SPX DOMAIN (Chaetomium thermophilum)	5 / 12	PHE A 153 LEU A 112 PHE A 115 ASP A 59 ILE A 144	None	1.33A	6dwnA-5ijjA: undetectable	6dwnA-5ijjA: 19.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YA4_B_CTXB2_1","CES1 PROTEIN","5ijj","SPX DOMAIN","Chaetomium thermophilum",5,"VAL A 159;SER A 107;LEU A 112;LEU A  76;LEU A 163","None","1.26A","1ya4B-5ijjA:undetectable","1ya4B-5ijjA:15.34"],["2BDM_A_TMIA502_1","CYTOCHROME P450 2B4","5ijj","SPX DOMAIN","Chaetomium thermophilum",5,"LEU A 105;LEU A 102;ILE A 166;ILE A 162;THR A  82","None","1.04A","2bdmA-5ijjA:undetectable","2bdmA-5ijjA:18.75"],["2Q63_A_1UNA1001_2","PROTEASE RETROPEPSIN","5ijj","SPX DOMAIN","Chaetomium thermophilum",3,"ARG A 142;ASN A  54;THR A 127","ACT A 503 (-3.9A);EDO A 501 (-3.2A);None","0.86A","2q63A-5ijjA:undetectable","2q63A-5ijjA:22.35"],["2VL2_B_BEZB1162_0","PEROXIREDOXIN-5","5ijj","SPX DOMAIN","Chaetomium thermophilum",4,"THR A 127;LEU A  44;PHE A  48;THR A 137","None;None;ACT A 503 ( 3.7A);None","1.04A","2vl2B-5ijjA:undetectable","2vl2B-5ijjA:22.93"],["3KVR_B_URFB2011_1","URIDINE PHOSPHORYLASE","5ijj","SPX DOMAIN","Chaetomium thermophilum",5,"GLY A 100;GLU A  97;LEU A 102;LEU A 103;ILE A 170","None","1.27A","3kvrB-5ijjA:undetectable","3kvrB-5ijjA:18.75"],["3NBQ_A_URFA400_1","URIDINE PHOSPHORYLASE 1","5ijj","SPX DOMAIN","Chaetomium thermophilum",5,"GLY A 100;GLU A  97;LEU A 102;LEU A 103;ILE A 170","None","1.38A","3nbqA-5ijjA:undetectable","3nbqA-5ijjA:19.52"],["5FA8_A_SAMA301_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE","5ijj","SPX DOMAIN","Chaetomium thermophilum",5,"GLY A 116;ILE A 118;ARG A 120;PHE A 115;LEU A  55","None","1.14A","5fa8A-5ijjA:undetectable","5fa8A-5ijjA:19.70"],["6DWN_A_AQ4A602_0","CYTOCHROME P450 1A1","5ijj","SPX DOMAIN","Chaetomium thermophilum",5,"PHE A 153;LEU A 112;PHE A 115;ASP A  59;ILE A 144","None","1.33A","6dwnA-5ijjA:undetectable","6dwnA-5ijjA:19.57"]]