SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ijv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		3 / 3 VAL H 136
VAL H  34
TRP H 134
 None
 0.90A 1av2C-5ijvH:
undetectable
1av2D-5ijvH:
undetectable		 1av2C-5ijvH:
5.39
1av2D-5ijvH:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		3 / 3 VAL H  34
TRP H  47
TRP H 134
 None
 0.94A 1c4dA-5ijvH:
undetectable
1c4dB-5ijvH:
undetectable		 1c4dA-5ijvH:
5.39
1c4dB-5ijvH:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		3 / 3 VAL H  34
TRP H 134
TRP H  47
 None
 1.33A 1c4dA-5ijvH:
undetectable
1c4dB-5ijvH:
undetectable		 1c4dA-5ijvH:
5.39
1c4dB-5ijvH:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		3 / 3 VAL H 136
VAL H  34
TRP H 134
 None
 0.87A 1w5uC-5ijvH:
undetectable
1w5uD-5ijvH:
undetectable		 1w5uC-5ijvH:
5.39
1w5uD-5ijvH:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		3 / 3 VAL H  34
TRP H 134
VAL H 136
 None
 0.96A 2izqA-5ijvH:
undetectable
2izqB-5ijvH:
undetectable		 2izqA-5ijvH:
5.39
2izqB-5ijvH:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		5 / 12 VAL H 199
VAL H 218
SER H 216
ASN H 232
ASN H 191
 None
 1.39A 2y03A-5ijvH:
undetectable		 2y03A-5ijvH:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		5 / 12 VAL H 199
VAL H 218
SER H 216
ASN H 232
ASN H 191
 None
 1.43A 2y03B-5ijvH:
undetectable		 2y03B-5ijvH:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		3 / 3 VAL H 136
VAL H  34
TRP H 134
 None
 0.90A 3l8lC-5ijvH:
undetectable
3l8lD-5ijvH:
undetectable		 3l8lC-5ijvH:
5.39
3l8lD-5ijvH:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		5 / 10 VAL H 199
VAL H 218
SER H 216
ASN H 232
ASN H 191
 None
 1.48A 4ldoA-5ijvH:
undetectable		 4ldoA-5ijvH:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		4 / 4 TYR H  59
THR H  57
GLY H  49
LEU H  80
 None
 1.12A 4w5nA-5ijvH:
undetectable		 4w5nA-5ijvH:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		5 / 11 VAL H 242
THR H 240
VAL H 246
ALA H 154
VAL H 188
 None
 1.04A 6dryA-5ijvH:
undetectable		 6dryA-5ijvH:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5ijv BOVINE FAB E03 HEAVY
CHAIN
(Bos
taurus) 		5 / 12 VAL H 199
VAL H 218
SER H 216
ASN H 232
ASN H 191
 None
 1.42A 6h7mB-5ijvH:
undetectable		 6h7mB-5ijvH:
15.23