SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ijw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.04A 1c9sP-5ijwA:
undetectable
1c9sQ-5ijwA:
undetectable		 1c9sP-5ijwA:
14.49
1c9sQ-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.13A 1gtfJ-5ijwA:
undetectable
1gtfK-5ijwA:
undetectable		 1gtfJ-5ijwA:
14.49
1gtfK-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.04A 1gtfQ-5ijwA:
undetectable
1gtfR-5ijwA:
undetectable		 1gtfQ-5ijwA:
14.49
1gtfR-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.05A 1gtfS-5ijwA:
undetectable
1gtfT-5ijwA:
undetectable		 1gtfS-5ijwA:
14.49
1gtfT-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.06A 1gtnT-5ijwA:
undetectable
1gtnU-5ijwA:
undetectable		 1gtnT-5ijwA:
14.49
1gtnU-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.09A 1utdE-5ijwA:
undetectable
1utdF-5ijwA:
undetectable		 1utdE-5ijwA:
14.49
1utdF-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.08A 1utdH-5ijwA:
undetectable
1utdI-5ijwA:
undetectable		 1utdH-5ijwA:
14.49
1utdI-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 HIS A 188
THR A 123
THR A 120
GLY A 185
THR A 187
 DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
None
DGL  A 301 (-3.0A)
 1.06A 1utdS-5ijwA:
undetectable
1utdT-5ijwA:
undetectable		 1utdS-5ijwA:
14.49
1utdT-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.08A 1utdL-5ijwA:
undetectable
1utdV-5ijwA:
undetectable		 1utdL-5ijwA:
14.49
1utdV-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 ALA A  86
TYR A  90
ARG A  89
PHE A  11
 None
 1.10A 2ajvH-5ijwA:
undetectable
2ajvL-5ijwA:
undetectable		 2ajvH-5ijwA:
21.99
2ajvL-5ijwA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 ILE A  24
GLY A   9
PHE A  11
VAL A  98
LEU A  18
 None
 1.14A 3elzB-5ijwA:
undetectable		 3elzB-5ijwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 262
ASP A  26
LEU A  18
LEU A 259
GLY A 260
 None
 1.39A 3g1uC-5ijwA:
2.6		 3g1uC-5ijwA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU A 243
LEU A  63
ARG A  66
ILE A  24
LEU A  18
 None
 1.26A 3olsB-5ijwA:
undetectable		 3olsB-5ijwA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 CYH A  82
TYR A  90
ILE A  59
ILE A  73
 None
 1.00A 4afgD-5ijwA:
undetectable
4afgE-5ijwA:
undetectable		 4afgD-5ijwA:
19.86
4afgE-5ijwA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_A_LURA201_1
(TRANSTHYRETIN)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		4 / 4 LYS A  69
LEU A 226
ALA A  70
VAL A  72
 None
 1.22A 4ik6A-5ijwA:
undetectable		 4ik6A-5ijwA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU A 243
LEU A  63
ARG A  66
ILE A  24
LEU A  18
 None
 1.23A 4j24C-5ijwA:
undetectable		 4j24C-5ijwA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU A 243
LEU A  63
ARG A  66
ILE A  24
LEU A  18
 None
 1.26A 4j26B-5ijwA:
undetectable		 4j26B-5ijwA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A  33
ALA A 238
LEU A 221
LEU A 217
ILE A   8
 None
 1.05A 4m2xC-5ijwA:
undetectable		 4m2xC-5ijwA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ARG A 104
GLU A  97
ARG A 219
 None
 0.90A 4mwvA-5ijwA:
undetectable		 4mwvA-5ijwA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLY A  14
ASP A  12
GLU A 243
VAL A  68
 None
DGL  A 301 (-3.3A)
None
None
 1.17A 4nkvD-5ijwA:
undetectable		 4nkvD-5ijwA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 262
ASP A  26
LEU A  18
LEU A 259
GLY A 260
 None
 1.44A 4pfjB-5ijwA:
undetectable		 4pfjB-5ijwA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		4 / 4 LEU A 224
VAL A 220
GLU A 223
ARG A 219
 None
 1.11A 4ww7A-5ijwA:
undetectable		 4ww7A-5ijwA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 VAL A 103
TYR A 129
ALA A 132
 None
 0.33A 4ybnA-5ijwA:
undetectable		 4ybnA-5ijwA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5eevA-5ijwA:
undetectable
5eevB-5ijwA:
undetectable		 5eevA-5ijwA:
14.49
5eevB-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5eewA-5ijwA:
undetectable
5eewB-5ijwA:
undetectable		 5eewA-5ijwA:
14.49
5eewB-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5eexA-5ijwA:
undetectable
5eexB-5ijwA:
undetectable		 5eexA-5ijwA:
14.49
5eexB-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5eeyA-5ijwA:
undetectable
5eeyB-5ijwA:
undetectable		 5eeyA-5ijwA:
14.49
5eeyB-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5eezA-5ijwA:
undetectable
5eezB-5ijwA:
undetectable		 5eezA-5ijwA:
14.49
5eezB-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5ef0A-5ijwA:
undetectable
5ef0B-5ijwA:
undetectable		 5ef0A-5ijwA:
14.49
5ef0B-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5ef1A-5ijwA:
undetectable
5ef1B-5ijwA:
undetectable		 5ef1A-5ijwA:
14.49
5ef1B-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5ef2A-5ijwA:
undetectable
5ef2B-5ijwA:
undetectable		 5ef2A-5ijwA:
14.49
5ef2B-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 185
THR A 187
HIS A 188
THR A 123
THR A 120
 None
DGL  A 301 (-3.0A)
DGL  A 301 (-4.4A)
None
DGL  A 301 (-3.5A)
 1.12A 5ef3A-5ijwA:
undetectable
5ef3B-5ijwA:
undetectable		 5ef3A-5ijwA:
14.49
5ef3B-5ijwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5ijw GLUTAMATE RACEMASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 PRO A   7
LEU A  71
ILE A  73
ALA A  78
VAL A  36
 None
 1.25A 5m0oA-5ijwA:
undetectable		 5m0oA-5ijwA:
20.33