SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ik2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 7 ALA A 197
SER A 227
THR A 225
VAL A 223
 None
 0.82A 1dvxB-5ik2A:
undetectable		 1dvxB-5ik2A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDT_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 5ik2 ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum) 		5 / 11 VAL G 118
LEU G 230
GLU G 148
SER G 141
GLU G 237
 None
 1.36A 1fdtA-5ik2G:
undetectable		 1fdtA-5ik2G:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ik2 ATP SYNTHASE EPSILON
CHAIN
(Caldalkalibacill
us
thermarum) 		5 / 9 VAL H  63
GLY H  66
ALA H  25
THR H  43
ILE H  77
 None
 1.17A 1gtnL-5ik2H:
undetectable
1gtnM-5ik2H:
undetectable		 1gtnL-5ik2H:
22.46
1gtnM-5ik2H:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		5 / 9 ALA A 217
ASP A 216
GLY A 105
ILE A 222
VAL A 208
 None
 1.12A 1hpvB-5ik2A:
undetectable		 1hpvB-5ik2A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 5ik2 ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum) 		5 / 12 ILE G 140
ILE G 149
ALA G 229
TYR G 227
GLU G 148
 None
 1.37A 1ki7B-5ik2G:
undetectable		 1ki7B-5ik2G:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		5 / 12 ILE A 150
ASP A 154
LEU A 344
GLY A 149
ASN A 185
 None
 1.17A 1likA-5ik2A:
undetectable		 1likA-5ik2A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 8 ARG A 296
TYR A 270
GLU A 130
GLN A  64
 None
 0.93A 1nx9A-5ik2A:
undetectable		 1nx9A-5ik2A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 8 ARG A 296
TYR A 270
GLU A 130
GLN A  64
 None
 0.93A 1nx9B-5ik2A:
undetectable		 1nx9B-5ik2A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 8 ARG A 296
TYR A 270
GLU A 130
GLN A  64
 None
 0.93A 1nx9C-5ik2A:
undetectable		 1nx9C-5ik2A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 8 ARG A 296
TYR A 270
GLU A 130
GLN A  64
 None
 0.93A 1nx9D-5ik2A:
undetectable		 1nx9D-5ik2A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		3 / 3 ASP A 452
PHE A 498
ARG A 455
 None
 0.86A 2a3aA-5ik2A:
undetectable		 2a3aA-5ik2A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum;
Caldalkalibacill
us
thermarum) 		5 / 12 ARG G   5
PHE A 343
ALA A 323
ILE A 168
ILE A 335
 None
 1.17A 2bjfA-5ik2G:
undetectable		 2bjfA-5ik2G:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 5ik2 ATP SYNTHASE EPSILON
CHAIN
ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum) 		5 / 12 ALA H  79
ASP H  80
GLY H  65
GLY H  66
THR G 224
 None
 1.07A 2c49A-5ik2H:
undetectable		 2c49A-5ik2H:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 5ik2 ATP SYNTHASE GAMMA
CHAIN
ATP SYNTHASE EPSILON
CHAIN
(Caldalkalibacill
us
thermarum;
Caldalkalibacill
us
thermarum) 		3 / 3 THR G  38
PRO H  11
TYR G 227
 None
 0.68A 2dxrA-5ik2G:
undetectable		 2dxrA-5ik2G:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum;
Caldalkalibacill
us
thermarum) 		5 / 12 ARG G   5
PHE A 343
ALA A 323
ILE A 168
ILE A 335
 None
 1.14A 2rlcA-5ik2G:
undetectable		 2rlcA-5ik2G:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 8 SER A 362
THR A 338
PRO A 317
LEU A 263
 None
 1.15A 2v0zO-5ik2A:
undetectable		 2v0zO-5ik2A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		3 / 3 GLU A 486
ASP A 488
TYR A 438
 None
 0.80A 2yvlB-5ik2A:
2.5		 2yvlB-5ik2A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 6 THR A 148
GLN A 186
LEU A 316
LEU A 257
 None
 1.06A 3bgdA-5ik2A:
2.0		 3bgdA-5ik2A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 6 ALA A 197
SER A 227
THR A 225
VAL A 223
 None
 0.81A 3d2tB-5ik2A:
undetectable		 3d2tB-5ik2A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 4 GLU A 345
GLY A 169
THR A 321
GLU A 320
 None
 1.16A 3e9xA-5ik2A:
undetectable		 3e9xA-5ik2A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 4 ILE A 178
ARG A 383
ILE A 153
THR A 173
 None
None
None
ADP  A 600 (-4.4A)
 1.29A 3ia4C-5ik2A:
undetectable		 3ia4C-5ik2A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 5ik2 ATP SYNTHASE EPSILON
CHAIN
(Caldalkalibacill
us
thermarum) 		4 / 7 GLU H  86
LEU H 128
LYS H  94
ASN H 132
 None
 1.40A 3k8mA-5ik2H:
undetectable		 3k8mA-5ik2H:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 5ik2 ATP SYNTHASE EPSILON
CHAIN
(Caldalkalibacill
us
thermarum) 		4 / 7 GLU H  86
LEU H 128
LYS H  94
ASN H 132
 None
 1.37A 3k8mB-5ik2H:
undetectable		 3k8mB-5ik2H:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		3 / 3 LYS A 303
ARG A 161
LYS A 376
 None
 1.48A 3okxA-5ik2A:
3.1		 3okxA-5ik2A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 7 ALA A 197
SER A 227
THR A 225
VAL A 223
 None
 0.93A 3ozkB-5ik2A:
undetectable		 3ozkB-5ik2A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 5ik2 ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum) 		4 / 6 THR G  82
SER G 100
TYR G 131
ASP G 124
 None
 1.04A 3q70A-5ik2G:
undetectable		 3q70A-5ik2G:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5ik2 ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum) 		5 / 11 ILE G 115
ILE G 170
ALA G 117
THR G  82
VAL G  99
 None
 1.04A 3tmzA-5ik2G:
1.8		 3tmzA-5ik2G:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		5 / 12 ASP A 385
SER A 364
ILE A 157
THR A 416
ALA A 370
 None
 1.05A 3ua1A-5ik2A:
undetectable		 3ua1A-5ik2A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5ik2 ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum) 		5 / 12 LEU G 189
MET G  67
ALA G 222
ILE G 226
ILE G 157
 None
 1.12A 3ut5B-5ik2G:
undetectable		 3ut5B-5ik2G:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 6 ARG A 465
ASP A 423
GLU A 418
LEU A 461
 None
 1.36A 4ax8A-5ik2A:
undetectable		 4ax8A-5ik2A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 5ik2 ATP SYNTHASE EPSILON
CHAIN
ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum) 		4 / 7 THR G  38
VAL H   9
PRO H  11
TYR G 227
 None
 0.75A 4forA-5ik2G:
undetectable		 4forA-5ik2G:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 5ik2 ATP SYNTHASE EPSILON
CHAIN
ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum) 		4 / 5 THR G  38
VAL H   9
PRO H  11
TYR G 227
 None
 0.76A 4grkA-5ik2G:
undetectable		 4grkA-5ik2G:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 5ik2 ATP SYNTHASE EPSILON
CHAIN
(Caldalkalibacill
us
thermarum) 		5 / 8 ILE H  77
GLU H  87
ALA H  25
VAL H  63
VAL H 130
 None
 0.97A 4jltA-5ik2H:
undetectable		 4jltA-5ik2H:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		5 / 12 GLN A 113
LEU A  76
MET A  60
THR A  91
MET A  95
 None
 1.41A 4okxA-5ik2A:
undetectable		 4okxA-5ik2A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		5 / 12 GLN A 113
LEU A  76
MET A  60
THR A  91
MET A  95
 None
 1.31A 4olmA-5ik2A:
undetectable		 4olmA-5ik2A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		5 / 12 GLY A  72
ASN A  65
ILE A  32
GLN A  33
HIS A  42
 None
 1.38A 4pooB-5ik2A:
3.1		 4pooB-5ik2A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 8 PHE A 291
THR A 338
SER A 336
TYR A 260
 None
 1.21A 4qb9D-5ik2A:
undetectable		 4qb9D-5ik2A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 5ik2 ATP SYNTHASE EPSILON
CHAIN
(Caldalkalibacill
us
thermarum) 		6 / 11 LEU H  84
ALA H  82
VAL H  50
ILE H  77
THR H  59
ILE H  61
 None
 1.28A 4rvjA-5ik2H:
undetectable		 4rvjA-5ik2H:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 5ik2 ATP SYNTHASE EPSILON
CHAIN
(Caldalkalibacill
us
thermarum) 		6 / 11 LEU H  84
ALA H  82
VAL H  50
ILE H  77
THR H  59
ILE H  61
 None
 1.26A 4rvjC-5ik2H:
undetectable		 4rvjC-5ik2H:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5ik2 ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum) 		4 / 6 PHE G 238
LYS G 234
LEU G 231
ARG G 241
 None
 1.01A 4yv5B-5ik2G:
1.1		 4yv5B-5ik2G:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5ik2 ATP SYNTHASE GAMMA
CHAIN
(Caldalkalibacill
us
thermarum) 		4 / 6 PHE G 238
LYS G 234
LEU G 231
ARG G 241
 None
 1.05A 4yv5A-5ik2G:
undetectable		 4yv5A-5ik2G:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		5 / 12 ALA A 267
PHE A 291
THR A 332
THR A 338
LEU A 298
 None
 1.11A 4z7fC-5ik2A:
undetectable		 4z7fC-5ik2A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		5 / 12 ILE A 129
LEU A  52
MET A  60
MET A  62
ALA A  63
 None
 1.24A 5fctB-5ik2A:
undetectable		 5fctB-5ik2A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		5 / 12 ASP A 385
SER A 364
ILE A 157
THR A 416
ALA A 370
 None
 1.00A 5vcgA-5ik2A:
undetectable		 5vcgA-5ik2A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 5ik2 ATP SYNTHASE SUBUNIT
ALPHA
(Caldalkalibacill
us
thermarum) 		4 / 5 PRO A  78
VAL A  59
GLY A  72
VAL A  34
 None
 1.01A 6ak3B-5ik2A:
undetectable		 6ak3B-5ik2A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 5ik2 ATP SYNTHASE EPSILON
CHAIN
(Caldalkalibacill
us
thermarum) 		3 / 3 ARG H 116
ARG H 106
ARG H  99
 None
 0.88A 6bplA-5ik2H:
4.1
6bplB-5ik2H:
5.0		 6bplA-5ik2H:
21.58
6bplB-5ik2H:
21.58