SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ikg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		5 / 11 PHE A 139
PHE A  35
ILE A  43
LEU A  76
PHE A  68
 None
 1.05A 1z11B-5ikgA:
undetectable		 1z11B-5ikgA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR6_A_DM2A2002_1
(ACRB)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		5 / 9 SER A 150
GLN A 218
PHE A 216
GLY A 431
ILE A 114
 None
 1.34A 2dr6A-5ikgA:
0.7		 2dr6A-5ikgA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		5 / 9 GLN A 218
PHE A 216
GLY A 431
ILE A 114
VAL A 117
 None
 1.16A 2drdA-5ikgA:
undetectable		 2drdA-5ikgA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		4 / 6 TRP A 207
GLY A  83
GLY A 196
PHE A 435
 None
 0.86A 2qx6A-5ikgA:
undetectable
2qx6B-5ikgA:
undetectable		 2qx6A-5ikgA:
21.48
2qx6B-5ikgA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		5 / 12 SER A  97
GLY A 431
TYR A 433
GLU A 432
HIS A 371
 None
 1.14A 3f8wA-5ikgA:
undetectable		 3f8wA-5ikgA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		3 / 3 ALA A 303
ARG A 306
LYS A 387
 None
 1.03A 3kp3B-5ikgA:
undetectable		 3kp3B-5ikgA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		4 / 8 ALA A 250
LEU A 247
ASP A 269
SER A 258
 None
 0.93A 3qj7A-5ikgA:
undetectable
3qj7D-5ikgA:
undetectable		 3qj7A-5ikgA:
21.55
3qj7D-5ikgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		5 / 11 PHE A  27
ASN A  30
ILE A  29
THR A  71
LEU A 146
 None
 1.08A 3t3rA-5ikgA:
undetectable		 3t3rA-5ikgA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		4 / 8 GLN A 424
GLY A 403
GLY A 393
ASN A 380
 None
 0.86A 3v3nB-5ikgA:
undetectable		 3v3nB-5ikgA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		4 / 8 GLN A 424
GLY A 403
GLY A 393
ASN A 380
 None
 0.87A 3v3nC-5ikgA:
undetectable		 3v3nC-5ikgA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		4 / 4 LEU A  76
ILE A  66
GLY A  72
PHE A  27
 None
 1.07A 4dc3A-5ikgA:
undetectable		 4dc3A-5ikgA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		4 / 8 ILE A  13
PHE A 435
TRP A 207
GLY A 196
 None
 0.98A 4fgjA-5ikgA:
undetectable
4fgjB-5ikgA:
undetectable		 4fgjA-5ikgA:
21.83
4fgjB-5ikgA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		4 / 8 ASN A 328
GLN A 172
GLN A 365
ILE A 193
 None
 0.97A 4iilA-5ikgA:
undetectable		 4iilA-5ikgA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		5 / 12 ARG A 217
ALA A 151
ILE A 114
TYR A 147
GLY A 111
 None
 1.35A 4l9qA-5ikgA:
undetectable		 4l9qA-5ikgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		5 / 11 GLY A 326
ALA A 325
THR A 308
ILE A 330
THR A 376
 None
None
HEM  A 501 (-3.5A)
None
None
 0.96A 4qgiA-5ikgA:
undetectable		 4qgiA-5ikgA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		4 / 5 ILE A 143
LEU A  73
GLY A  72
PHE A  68
 None
 0.95A 5kmdC-5ikgA:
undetectable
5kmdD-5ikgA:
undetectable		 5kmdC-5ikgA:
19.36
5kmdD-5ikgA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		5 / 9 ILE A 114
PHE A 216
GLY A 430
PHE A 109
GLY A 111
 None
 1.05A 6awoA-5ikgA:
undetectable		 6awoA-5ikgA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		5 / 9 ILE A 114
PHE A 216
GLY A 430
PHE A 109
GLY A 111
 None
 1.04A 6awqA-5ikgA:
undetectable		 6awqA-5ikgA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		5 / 12 GLY A 169
TYR A 337
PHE A  26
GLY A 431
LEU A 219
 HEM  A 501 (-3.4A)
None
None
None
HEM  A 501 ( 4.2A)
 1.23A 6e8qA-5ikgA:
undetectable		 6e8qA-5ikgA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 5ikg DYE-DECOLORIZING
PEROXIDASE
(Auricularia
auricula-judae) 		4 / 5 GLN A  91
THR A 308
HIS A 304
LEU A 219
 None
HEM  A 501 (-3.5A)
HEM  A 501 (-3.4A)
HEM  A 501 ( 4.2A)
 1.36A 6gbnB-5ikgA:
undetectable		 6gbnB-5ikgA:
22.06