SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iki'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 6 LEU A 154
GLU A 116
LEU A 363
LEU A 146
 None
 0.92A 1mt1D-5ikiA:
undetectable
1mt1E-5ikiA:
undetectable		 1mt1D-5ikiA:
13.30
1mt1E-5ikiA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.17A 1v54A-5ikiA:
undetectable
1v54C-5ikiA:
undetectable		 1v54A-5ikiA:
21.56
1v54C-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.14A 1v54N-5ikiA:
undetectable
1v54P-5ikiA:
undetectable		 1v54N-5ikiA:
21.56
1v54P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.19A 1v55A-5ikiA:
undetectable
1v55C-5ikiA:
undetectable		 1v55A-5ikiA:
21.56
1v55C-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.18A 2dyrA-5ikiA:
undetectable
2dyrC-5ikiA:
undetectable		 2dyrA-5ikiA:
21.56
2dyrC-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 2dyrN-5ikiA:
undetectable
2dyrP-5ikiA:
undetectable		 2dyrN-5ikiA:
21.56
2dyrP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.20A 2eijA-5ikiA:
undetectable
2eijC-5ikiA:
undetectable		 2eijA-5ikiA:
21.56
2eijC-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.17A 2eijN-5ikiA:
undetectable
2eijP-5ikiA:
undetectable		 2eijN-5ikiA:
21.56
2eijP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.18A 2eikA-5ikiA:
undetectable
2eikC-5ikiA:
undetectable		 2eikA-5ikiA:
21.56
2eikC-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.19A 2eikN-5ikiA:
undetectable
2eikP-5ikiA:
undetectable		 2eikN-5ikiA:
21.56
2eikP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.17A 2eilA-5ikiA:
undetectable
2eilC-5ikiA:
undetectable		 2eilA-5ikiA:
21.56
2eilC-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.17A 2eilN-5ikiA:
undetectable
2eilP-5ikiA:
undetectable		 2eilN-5ikiA:
21.56
2eilP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.14A 2y69A-5ikiA:
undetectable
2y69C-5ikiA:
undetectable		 2y69A-5ikiA:
21.56
2y69C-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.17A 2y69C-5ikiA:
undetectable
2y69N-5ikiA:
undetectable
2y69P-5ikiA:
undetectable		 2y69C-5ikiA:
19.57
2y69N-5ikiA:
21.56
2y69P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLP_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		5 / 11 LEU A 400
ASN A 254
LEU A 252
LEU A 260
MET A 284
 None
 1.28A 2ylpA-5ikiA:
2.3		 2ylpA-5ikiA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 3abkA-5ikiA:
undetectable
3abkC-5ikiA:
undetectable		 3abkA-5ikiA:
21.56
3abkC-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.12A 3abkN-5ikiA:
undetectable
3abkP-5ikiA:
undetectable		 3abkN-5ikiA:
21.56
3abkP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 3ablA-5ikiA:
undetectable
3ablC-5ikiA:
undetectable
3ablP-5ikiA:
undetectable		 3ablA-5ikiA:
21.56
3ablC-5ikiA:
19.57
3ablP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 3ablC-5ikiA:
undetectable
3ablN-5ikiA:
undetectable
3ablP-5ikiA:
undetectable		 3ablC-5ikiA:
19.57
3ablN-5ikiA:
21.56
3ablP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 3abmA-5ikiA:
undetectable
3abmC-5ikiA:
undetectable
3abmP-5ikiA:
undetectable		 3abmA-5ikiA:
21.56
3abmC-5ikiA:
19.57
3abmP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 3abmN-5ikiA:
undetectable
3abmP-5ikiA:
undetectable		 3abmN-5ikiA:
21.56
3abmP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.14A 3ag2A-5ikiA:
undetectable
3ag2C-5ikiA:
undetectable		 3ag2A-5ikiA:
21.56
3ag2C-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.14A 3ag2N-5ikiA:
undetectable
3ag2P-5ikiA:
undetectable		 3ag2N-5ikiA:
21.56
3ag2P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.17A 3ag3A-5ikiA:
undetectable
3ag3C-5ikiA:
undetectable		 3ag3A-5ikiA:
21.56
3ag3C-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.13A 3ag3N-5ikiA:
undetectable
3ag3P-5ikiA:
undetectable		 3ag3N-5ikiA:
21.56
3ag3P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 3ag4A-5ikiA:
undetectable
3ag4C-5ikiA:
undetectable		 3ag4A-5ikiA:
21.56
3ag4C-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 3ag4N-5ikiA:
undetectable
3ag4P-5ikiA:
undetectable		 3ag4N-5ikiA:
21.56
3ag4P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.14A 3asnC-5ikiA:
undetectable
3asnN-5ikiA:
undetectable
3asnP-5ikiA:
undetectable		 3asnC-5ikiA:
19.57
3asnN-5ikiA:
21.56
3asnP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 3asoA-5ikiA:
undetectable
3asoC-5ikiA:
undetectable
3asoP-5ikiA:
undetectable		 3asoA-5ikiA:
21.56
3asoC-5ikiA:
19.57
3asoP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.12A 3asoC-5ikiA:
undetectable
3asoN-5ikiA:
undetectable
3asoP-5ikiA:
undetectable		 3asoC-5ikiA:
19.57
3asoN-5ikiA:
21.56
3asoP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_A_4PZA501_1
(CYTOCHROME P450 2E1)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		3 / 3 ALA A 243
THR A 247
CYH A 355
 HEM  A 501 (-3.5A)
HEM  A 501 (-3.7A)
HEM  A 501 (-2.2A)
 0.49A 3e4eA-5ikiA:
27.7		 3e4eA-5ikiA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		3 / 3 ALA A 243
THR A 247
CYH A 355
 HEM  A 501 (-3.5A)
HEM  A 501 (-3.7A)
HEM  A 501 (-2.2A)
 0.46A 3e4eB-5ikiA:
27.7		 3e4eB-5ikiA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		5 / 12 LEU A 346
ARG A 286
TYR A  49
PHE A 329
LEU A  30
 None
 1.15A 3gwuA-5ikiA:
undetectable		 3gwuA-5ikiA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.12A 3wg7A-5ikiA:
undetectable
3wg7C-5ikiA:
undetectable
3wg7P-5ikiA:
undetectable		 3wg7A-5ikiA:
21.56
3wg7C-5ikiA:
19.57
3wg7P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.13A 3wg7C-5ikiA:
undetectable
3wg7N-5ikiA:
undetectable
3wg7P-5ikiA:
undetectable		 3wg7C-5ikiA:
19.57
3wg7N-5ikiA:
21.56
3wg7P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 3x2qA-5ikiA:
undetectable
3x2qC-5ikiA:
undetectable
3x2qP-5ikiA:
undetectable		 3x2qA-5ikiA:
21.56
3x2qC-5ikiA:
19.57
3x2qP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.18A 3x2qC-5ikiA:
undetectable
3x2qN-5ikiA:
undetectable
3x2qP-5ikiA:
undetectable		 3x2qC-5ikiA:
19.57
3x2qN-5ikiA:
21.56
3x2qP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		5 / 12 ASP A 231
ALA A 192
TYR A 195
TYR A 196
THR A 237
 None
 1.26A 4mm6A-5ikiA:
undetectable		 4mm6A-5ikiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 5 LEU A 294
ASP A 295
LEU A  56
THR A  89
 HEM  A 501 (-4.2A)
None
None
HEM  A 501 (-4.1A)
 1.13A 4wozF-5ikiA:
undetectable
4wozH-5ikiA:
undetectable		 4wozF-5ikiA:
22.57
4wozH-5ikiA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		5 / 10 SER A 144
LEU A 369
SER A 249
LEU A 252
LEU A 259
 None
 1.00A 4yiaA-5ikiA:
undetectable		 4yiaA-5ikiA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 5b1aA-5ikiA:
undetectable
5b1aC-5ikiA:
undetectable
5b1aP-5ikiA:
undetectable		 5b1aA-5ikiA:
21.56
5b1aC-5ikiA:
19.57
5b1aP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.13A 5b1aN-5ikiA:
undetectable
5b1aP-5ikiA:
undetectable		 5b1aN-5ikiA:
21.56
5b1aP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 5b1bA-5ikiA:
undetectable
5b1bC-5ikiA:
undetectable
5b1bP-5ikiA:
undetectable		 5b1bA-5ikiA:
21.56
5b1bC-5ikiA:
19.57
5b1bP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 5b1bN-5ikiA:
undetectable
5b1bP-5ikiA:
undetectable		 5b1bN-5ikiA:
21.56
5b1bP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.13A 5b3sA-5ikiA:
undetectable
5b3sC-5ikiA:
undetectable
5b3sP-5ikiA:
undetectable		 5b3sA-5ikiA:
21.56
5b3sC-5ikiA:
19.57
5b3sP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.12A 5b3sN-5ikiA:
undetectable
5b3sP-5ikiA:
undetectable		 5b3sN-5ikiA:
21.56
5b3sP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 5iy5A-5ikiA:
undetectable
5iy5C-5ikiA:
undetectable		 5iy5A-5ikiA:
21.56
5iy5C-5ikiA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.13A 5iy5C-5ikiA:
undetectable
5iy5N-5ikiA:
undetectable
5iy5P-5ikiA:
undetectable		 5iy5C-5ikiA:
19.18
5iy5N-5ikiA:
21.56
5iy5P-5ikiA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		5 / 12 ALA A 361
GLY A 357
LEU A 363
ALA A 365
PRO A 278
 HEM  A 501 (-3.5A)
HEM  A 501 (-3.5A)
None
None
None
 0.85A 5jglB-5ikiA:
undetectable		 5jglB-5ikiA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.11A 5w97A-5ikiA:
undetectable
5w97C-5ikiA:
undetectable
5w97c-5ikiA:
undetectable		 5w97A-5ikiA:
21.56
5w97C-5ikiA:
19.57
5w97c-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.14A 5wauA-5ikiA:
undetectable
5wauC-5ikiA:
undetectable
5wauc-5ikiA:
undetectable		 5wauA-5ikiA:
21.56
5wauC-5ikiA:
19.57
5wauc-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 5x19A-5ikiA:
undetectable
5x19C-5ikiA:
undetectable
5x19P-5ikiA:
undetectable		 5x19A-5ikiA:
21.56
5x19C-5ikiA:
19.57
5x19P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.12A 5x1fN-5ikiA:
undetectable
5x1fP-5ikiA:
undetectable		 5x1fN-5ikiA:
21.56
5x1fP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.13A 5xdqA-5ikiA:
undetectable
5xdqC-5ikiA:
undetectable
5xdqP-5ikiA:
undetectable		 5xdqA-5ikiA:
21.56
5xdqC-5ikiA:
19.57
5xdqP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.14A 5xdqC-5ikiA:
undetectable
5xdqN-5ikiA:
undetectable
5xdqP-5ikiA:
undetectable		 5xdqC-5ikiA:
19.57
5xdqN-5ikiA:
21.56
5xdqP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 5xdxC-5ikiA:
undetectable
5xdxN-5ikiA:
undetectable
5xdxP-5ikiA:
undetectable		 5xdxC-5ikiA:
19.38
5xdxN-5ikiA:
21.56
5xdxP-5ikiA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		5 / 12 ILE A 127
LEU A 270
LEU A 251
LEU A 142
PHE A 256
 None
None
HEM  A 501 ( 4.2A)
None
None
 1.27A 5xxiA-5ikiA:
29.2		 5xxiA-5ikiA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 5z84A-5ikiA:
undetectable
5z84C-5ikiA:
undetectable
5z84P-5ikiA:
undetectable		 5z84A-5ikiA:
21.56
5z84C-5ikiA:
19.57
5z84P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 5z85A-5ikiA:
undetectable
5z85C-5ikiA:
undetectable
5z85P-5ikiA:
undetectable		 5z85A-5ikiA:
21.56
5z85C-5ikiA:
19.57
5z85P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 5z86A-5ikiA:
undetectable
5z86C-5ikiA:
undetectable
5z86P-5ikiA:
undetectable		 5z86A-5ikiA:
21.56
5z86C-5ikiA:
19.57
5z86P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 5z86C-5ikiA:
undetectable
5z86N-5ikiA:
undetectable
5z86P-5ikiA:
undetectable		 5z86C-5ikiA:
19.57
5z86N-5ikiA:
21.56
5z86P-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 5zcoA-5ikiA:
undetectable
5zcoC-5ikiA:
undetectable
5zcoP-5ikiA:
undetectable		 5zcoA-5ikiA:
21.56
5zcoC-5ikiA:
19.57
5zcoP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 5zcoC-5ikiA:
undetectable
5zcoN-5ikiA:
undetectable
5zcoP-5ikiA:
undetectable		 5zcoC-5ikiA:
19.57
5zcoN-5ikiA:
21.56
5zcoP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.14A 5zcpA-5ikiA:
undetectable
5zcpC-5ikiA:
undetectable
5zcpP-5ikiA:
undetectable		 5zcpA-5ikiA:
21.56
5zcpC-5ikiA:
19.57
5zcpP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.16A 5zcpC-5ikiA:
undetectable
5zcpN-5ikiA:
undetectable
5zcpP-5ikiA:
undetectable		 5zcpC-5ikiA:
19.57
5zcpN-5ikiA:
21.56
5zcpP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 8 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.14A 5zcqA-5ikiA:
undetectable
5zcqC-5ikiA:
undetectable
5zcqP-5ikiA:
undetectable		 5zcqA-5ikiA:
21.56
5zcqC-5ikiA:
19.57
5zcqP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 5zcqN-5ikiA:
undetectable
5zcqP-5ikiA:
undetectable		 5zcqN-5ikiA:
21.56
5zcqP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.09A 6nmfN-5ikiA:
undetectable
6nmfP-5ikiA:
undetectable		 6nmfN-5ikiA:
21.56
6nmfP-5ikiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5iki CYTOCHROME P450(MEG)
(Bacillus
megaterium) 		4 / 7 TRP A 318
ASP A  42
THR A  43
TRP A  25
 None
 1.15A 6nmpN-5ikiA:
undetectable
6nmpP-5ikiA:
undetectable		 6nmpN-5ikiA:
21.56
6nmpP-5ikiA:
19.57