SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ikl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.06A 1c9sN-5iklB:
undetectable
1c9sO-5iklB:
undetectable
1c9sN-5iklB:
10.40
1c9sO-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 11 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.05A 1c9sP-5iklB:
undetectable
1c9sQ-5iklB:
undetectable
1c9sP-5iklB:
10.40
1c9sQ-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 9 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.06A 1c9sQ-5iklB:
undetectable
1c9sR-5iklB:
undetectable
1c9sQ-5iklB:
10.40
1c9sR-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
1.04A 1c9sL-5iklB:
undetectable
1c9sV-5iklB:
undetectable
1c9sL-5iklB:
10.40
1c9sV-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 9 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
1.05A 1gtfD-5iklB:
undetectable
1gtfE-5iklB:
undetectable
1gtfD-5iklB:
10.40
1gtfE-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
1.02A 1gtfJ-5iklB:
undetectable
1gtfK-5iklB:
undetectable
1gtfJ-5iklB:
10.40
1gtfK-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 11 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.03A 1gtfQ-5iklB:
undetectable
1gtfR-5iklB:
undetectable
1gtfQ-5iklB:
10.40
1gtfR-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 9 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.02A 1gtfR-5iklB:
undetectable
1gtfS-5iklB:
undetectable
1gtfR-5iklB:
10.40
1gtfS-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 11 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.03A 1gtfS-5iklB:
undetectable
1gtfT-5iklB:
undetectable
1gtfS-5iklB:
10.40
1gtfT-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 11 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.05A 1gtnT-5iklB:
undetectable
1gtnU-5iklB:
undetectable
1gtnT-5iklB:
10.40
1gtnU-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
4 / 6 ASN B 321
ASP B 324
GLY B 325
THR B 327
None
0.93A 1n4fA-5iklB:
undetectable
1n4fA-5iklB:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 ILE B 172
GLN B 169
LEU B 130
CYH B 105
LEU B 106
None
1.05A 1rjdA-5iklB:
undetectable
1rjdA-5iklB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 ILE B 172
GLN B 169
LEU B 130
CYH B 105
LEU B 106
None
1.06A 1rjdB-5iklB:
undetectable
1rjdB-5iklB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 ILE B 172
GLN B 169
LEU B 130
CYH B 105
LEU B 106
None
1.09A 1rjdC-5iklB:
undetectable
1rjdC-5iklB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.05A 1utdE-5iklB:
undetectable
1utdF-5iklB:
undetectable
1utdE-5iklB:
10.40
1utdF-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.05A 1utdH-5iklB:
undetectable
1utdI-5iklB:
undetectable
1utdH-5iklB:
10.40
1utdI-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.01A 1utdO-5iklB:
undetectable
1utdP-5iklB:
undetectable
1utdO-5iklB:
10.40
1utdP-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 11 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.04A 1utdP-5iklB:
undetectable
1utdQ-5iklB:
undetectable
1utdP-5iklB:
10.40
1utdQ-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 11 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.02A 1utdS-5iklB:
undetectable
1utdT-5iklB:
undetectable
1utdS-5iklB:
10.40
1utdT-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 378
ALA B 423
THR B 376
GLY B 343
THR B 327
None
1.04A 1utdU-5iklB:
undetectable
1utdV-5iklB:
undetectable
1utdU-5iklB:
10.40
1utdV-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 LEU B 124
ALA B 150
ILE B 119
ALA B 192
LEU B 197
None
1.17A 1xp0A-5iklB:
undetectable
1xp0A-5iklB:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 149
ALA B 150
GLY B  91
ILE B  93
ILE B 158
None
0.91A 2aquA-5iklB:
undetectable
2aquA-5iklB:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
3 / 3 SER B 186
THR B 143
GLN B 194
None
0.85A 2fk8A-5iklB:
undetectable
2fk8A-5iklB:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
4 / 4 SER B 186
GLY B 185
GLY B 148
GLY B 116
None
0.80A 3bogB-5iklB:
undetectable
3bogD-5iklB:
undetectable
3bogB-5iklB:
undetectable
3bogD-5iklB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
3 / 3 LYS B  89
LYS B  39
VAL B  36
None
1.02A 3brfA-5iklB:
undetectable
3brfA-5iklB:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
4 / 8 GLY B 426
ASN B 421
TRP B 499
TYR B 422
None
0.99A 3ccfA-5iklB:
undetectable
3ccfA-5iklB:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 149
ALA B 150
GLY B  91
ILE B  93
ILE B 158
None
0.92A 3ekyA-5iklB:
undetectable
3ekyA-5iklB:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
4 / 7 THR B 143
VAL B 183
THR B 181
VAL B 201
None
0.66A 3em0B-5iklB:
undetectable
3em0B-5iklB:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 LEU B 212
GLY B 232
ASP B 228
GLY B 185
VAL B 183
None
1.04A 3oxwA-5iklB:
undetectable
3oxwA-5iklB:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 LEU B 212
GLY B 232
ASP B 228
GLY B 185
VAL B 183
None
0.98A 3oxwC-5iklB:
undetectable
3oxwC-5iklB:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 VAL B 444
VAL B 453
GLY B 451
ALA B 450
LEU B 485
None
1.10A 3pghA-5iklB:
undetectable
3pghA-5iklB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 VAL B 444
VAL B 453
GLY B 451
ALA B 450
LEU B 485
None
1.03A 3rr3A-5iklB:
undetectable
3rr3A-5iklB:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 VAL B 444
VAL B 453
GLY B 451
ALA B 450
LEU B 485
None
1.02A 3rr3B-5iklB:
undetectable
3rr3B-5iklB:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 ALA B 258
VAL B 142
ILE B 100
GLY B 263
PRO B 178
None
0.98A 3so9B-5iklB:
undetectable
3so9B-5iklB:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 11 PHE B 319
ALA B 356
GLY B 340
GLY B 330
ILE B 342
None
1.05A 4dcmA-5iklB:
undetectable
4dcmA-5iklB:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 ILE B 133
ILE B 119
GLY B  90
SER B  73
ILE B  93
None
1.13A 4o1eA-5iklB:
undetectable
4o1eA-5iklB:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
6 / 11 GLY B 190
ILE B 119
THR B 118
GLY B 148
THR B 145
VAL B 183
None
1.44A 4qgiA-5iklB:
undetectable
4qgiA-5iklB:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
6 / 11 GLY B 190
ILE B 119
THR B 118
GLY B 149
THR B 145
VAL B 183
None
1.44A 4qgiA-5iklB:
undetectable
4qgiA-5iklB:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 11 LEU B 128
ASP B 430
GLN B 132
ILE B 434
ASP B 501
None
1.29A 4uuuA-5iklB:
undetectable
4uuuB-5iklB:
undetectable
4uuuA-5iklB:
13.24
4uuuB-5iklB:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 GLY B 352
ALA B 354
PHE B 319
PHE B 372
CYH B 425
None
1.38A 5cprB-5iklB:
undetectable
5cprB-5iklB:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
0.99A 5eevA-5iklB:
undetectable
5eevB-5iklB:
undetectable
5eevA-5iklB:
10.40
5eevB-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
0.99A 5eewA-5iklB:
undetectable
5eewB-5iklB:
undetectable
5eewA-5iklB:
10.40
5eewB-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
0.99A 5eexA-5iklB:
undetectable
5eexB-5iklB:
undetectable
5eexA-5iklB:
10.40
5eexB-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
0.99A 5eeyA-5iklB:
undetectable
5eeyB-5iklB:
undetectable
5eeyA-5iklB:
10.40
5eeyB-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
0.99A 5eezA-5iklB:
undetectable
5eezB-5iklB:
undetectable
5eezA-5iklB:
10.40
5eezB-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
0.99A 5ef0A-5iklB:
undetectable
5ef0B-5iklB:
undetectable
5ef0A-5iklB:
10.40
5ef0B-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
0.99A 5ef1A-5iklB:
undetectable
5ef1B-5iklB:
undetectable
5ef1A-5iklB:
10.40
5ef1B-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
0.99A 5ef2A-5iklB:
undetectable
5ef2B-5iklB:
undetectable
5ef2A-5iklB:
10.40
5ef2B-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 10 GLY B 343
THR B 327
GLY B 378
ALA B 423
THR B 376
None
0.99A 5ef3A-5iklB:
undetectable
5ef3B-5iklB:
undetectable
5ef3A-5iklB:
10.40
5ef3B-5iklB:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
4 / 8 GLY B  90
GLY B  91
VAL B  36
HIS B  81
None
0.75A 5f8yB-5iklB:
undetectable
5f8yB-5iklB:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
4 / 7 ASN B 321
VAL B 328
GLY B 346
ARG B 304
None
0.85A 5fpdA-5iklB:
undetectable
5fpdA-5iklB:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 9 LEU B 341
ARG B 309
ILE B   4
GLU B 315
PHE B 316
None
1.23A 5igzA-5iklB:
2.3
5igzA-5iklB:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 VAL B 444
VAL B 453
GLY B 451
ALA B 450
LEU B 485
None
0.99A 5iktA-5iklB:
undetectable
5iktA-5iklB:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
5 / 12 VAL B 444
VAL B 453
GLY B 451
ALA B 450
LEU B 485
None
1.02A 5iktB-5iklB:
undetectable
5iktB-5iklB:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
3 / 3 GLN B 326
THR B 349
ASP B 324
None
0.90A 5k9dA-5iklB:
undetectable
5k9dA-5iklB:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)
5ikl GERANYL-COA
CARBOXYLASE,
BETA-SUBUNIT

(Pseudomonas
aeruginosa)
4 / 8 THR B 143
SER B 108
THR B 145
SER B 110
None
1.02A 5l4eA-5iklB:
undetectable
5l4eB-5iklB:
undetectable
5l4eC-5iklB:
undetectable
5l4eD-5iklB:
undetectable
5l4eE-5iklB:
undetectable
5l4eA-5iklB:
22.43
5l4eB-5iklB:
22.43
5l4eC-5iklB:
22.43
5l4eD-5iklB:
22.43
5l4eE-5iklB:
22.43