SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ikz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 10 ALA A 948
PHE A 965
LEU A 783
VAL A 781
ILE A 875
None
1.19A 1claA-5ikzA:
undetectable
1claA-5ikzA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 11 PHE A   5
ARG A 433
LEU A 469
LEU A 379
ALA A 429
None
1.11A 1h9zA-5ikzA:
2.3
1h9zA-5ikzA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 11 VAL A 318
GLY A 325
HIS A 227
PHE A 352
GLU A 477
None
None
MG  A1201 (-4.1A)
None
MG  A1201 (-2.8A)
1.35A 1iolA-5ikzA:
undetectable
1iolA-5ikzA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 6 TYR A 301
VAL A 210
ILE A 209
LEU A 257
None
1.22A 1j96A-5ikzA:
5.6
1j96A-5ikzA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 8 VAL A 990
LEU A1053
TYR A1034
SER A1078
None
1.12A 1jtvA-5ikzA:
undetectable
1jtvA-5ikzA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 11 SER A 312
SER A 314
VAL A 383
PHE A 320
VAL A 318
None
1.28A 1q23J-5ikzA:
undetectable
1q23J-5ikzA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 12 SER A 872
SER A 869
ALA A 939
GLY A 937
VAL A 847
None
1.24A 1vpoH-5ikzA:
undetectable
1vpoL-5ikzA:
undetectable
1vpoH-5ikzA:
12.83
1vpoL-5ikzA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
3 / 3 PHE A 636
TYR A 568
TYR A 689
None
1.03A 1x70B-5ikzA:
undetectable
1x70B-5ikzA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 10 ALA A 424
ILE A 409
VAL A 463
ALA A 464
LEU A 379
None
1.15A 1xp0A-5ikzA:
undetectable
1xp0A-5ikzA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 6 SER A 935
GLU A 849
SER A 609
GLN A 632
GOL  A1202 ( 4.8A)
None
None
None
1.35A 2cl5B-5ikzA:
undetectable
2cl5B-5ikzA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 4 LEU A 729
THR A 730
ILE A 557
HIS A 724
None
1.04A 2jfaB-5ikzA:
0.9
2jfaB-5ikzA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 4 LEU A 684
PRO A 683
LEU A 729
ARG A 736
None
1.48A 2qd2A-5ikzA:
undetectable
2qd2A-5ikzA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 11 LEU A 459
ILE A 401
ALA A 381
GLU A 437
LEU A 469
None
1.25A 2v0mA-5ikzA:
undetectable
2v0mA-5ikzA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 8 TYR A 326
SER A 314
HIS A 225
SER A 312
None
None
MG  A1201 (-3.8A)
None
1.22A 2vmyA-5ikzA:
undetectable
2vmyB-5ikzA:
undetectable
2vmyA-5ikzA:
17.14
2vmyB-5ikzA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 6 SER A 935
GLU A 849
SER A 609
GLN A 632
GOL  A1202 ( 4.8A)
None
None
None
1.33A 2zvjA-5ikzA:
2.3
2zvjA-5ikzA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 12 SER A 973
LEU A 971
ASP A 945
GLN A 942
ALA A 941
None
1.19A 3a35B-5ikzA:
undetectable
3a35B-5ikzA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 5 TYR A 545
ALA A 725
ALA A 717
TYR A 715
None
1.28A 3d91A-5ikzA:
undetectable
3d91A-5ikzA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 12 SER A 312
ILE A 448
ILE A 356
VAL A 318
TYR A 326
None
1.41A 3g8iA-5ikzA:
undetectable
3g8iA-5ikzA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 4 LEU A 684
PRO A 683
LEU A 729
ARG A 736
None
1.38A 3hcoA-5ikzA:
undetectable
3hcoA-5ikzA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 9 LEU A 460
GLY A 471
ASP A 468
ILE A 465
ILE A 515
None
0.90A 3nu4B-5ikzA:
undetectable
3nu4B-5ikzA:
6.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 6 GLY A  13
GLU A 477
ASN A 277
GLU A 348
None
MG  A1201 (-2.8A)
None
None
1.03A 3vywC-5ikzA:
undetectable
3vywC-5ikzA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 12 GLY A 475
ALA A  10
ALA A 216
ASP A 499
ALA A 494
None
1.20A 4df3B-5ikzA:
undetectable
4df3B-5ikzA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 8 LEU A 751
THR A 836
ALA A 834
LEU A 832
None
0.93A 4ik6B-5ikzA:
undetectable
4ik6B-5ikzA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 5 PHE A 164
THR A 137
PHE A 139
ILE A 132
None
0.94A 4jx1E-5ikzA:
undetectable
4jx1E-5ikzA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
3 / 3 ARG A 999
ASP A1066
ASP A1061
None
0.73A 4kicB-5ikzA:
undetectable
4kicB-5ikzA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 4 VAL A 501
THR A 497
GLU A 219
GLU A 215
None
1.36A 4l78A-5ikzA:
undetectable
4l78A-5ikzA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
3 / 3 GLU A 871
TYR A 867
GLU A 549
None
0.75A 4ryaA-5ikzA:
undetectable
4ryaA-5ikzA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
3 / 3 ASP A 523
LEU A 709
GLY A 708
None
0.56A 4xmfA-5ikzA:
undetectable
4xmfA-5ikzA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 7 LEU A 729
LYS A 680
PRO A 681
GLU A 688
None
0.75A 4z4fA-5ikzA:
undetectable
4z4fA-5ikzA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 6 LEU A 729
LYS A 680
PRO A 681
GLU A 688
None
0.65A 4z4gA-5ikzA:
2.7
4z4gA-5ikzA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 5 ALA A 861
ARG A 714
HIS A 854
ALA A 720
None
1.33A 5a06C-5ikzA:
2.0
5a06D-5ikzA:
undetectable
5a06C-5ikzA:
15.58
5a06D-5ikzA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
3 / 3 ASP A 163
GLU A  53
SER A 125
None
0.57A 5bw4B-5ikzA:
undetectable
5bw4B-5ikzA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 12 PHE A 535
ILE A 693
LEU A 707
MET A 719
LEU A 722
None
1.10A 5byjA-5ikzA:
undetectable
5byjA-5ikzA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 5 PHE A 456
HIS A 421
LEU A 412
PRO A 455
None
1.36A 5csyB-5ikzA:
4.7
5csyB-5ikzA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
3 / 3 THR A1038
THR A1054
PHE A1057
None
0.92A 5cxvA-5ikzA:
undetectable
5cxvA-5ikzA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 8 VAL A 224
ALA A   9
GLY A 475
GLY A 496
None
0.89A 5e26C-5ikzA:
3.1
5e26D-5ikzA:
undetectable
5e26C-5ikzA:
14.58
5e26D-5ikzA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 5 SER A 935
GLU A 849
SER A 609
GLN A 632
GOL  A1202 ( 4.8A)
None
None
None
1.38A 5fhrB-5ikzA:
2.3
5fhrB-5ikzA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 12 ASP A 384
ARG A 406
PRO A 453
GLU A 350
HIS A 227
None
None
None
MG  A1201 (-3.8A)
MG  A1201 (-4.1A)
1.19A 5k7uA-5ikzA:
undetectable
5k7uA-5ikzA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
4 / 8 ALA A 978
THR A 993
TRP A 984
ALA A1051
None
0.95A 5x2tI-5ikzA:
undetectable
5x2tJ-5ikzA:
undetectable
5x2tK-5ikzA:
undetectable
5x2tL-5ikzA:
undetectable
5x2tI-5ikzA:
8.17
5x2tJ-5ikzA:
8.63
5x2tK-5ikzA:
8.17
5x2tL-5ikzA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 10 ASN A  91
LEU A  35
ALA A  30
LEU A  88
GLU A  63
None
1.09A 5y7pG-5ikzA:
undetectable
5y7pG-5ikzA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 12 ILE A 835
LEU A 833
GLY A 800
ALA A 802
LEU A 751
None
1.17A 5zwrA-5ikzA:
undetectable
5zwrA-5ikzA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 12 TYR A 568
ILE A 605
ARG A 644
LEU A 575
LEU A 641
None
1.37A 5zwrB-5ikzA:
undetectable
5zwrB-5ikzA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 12 THR A   8
ASP A 478
LEU A 460
GLY A 471
MET A 378
None
1.48A 6aphA-5ikzA:
2.6
6aphA-5ikzA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis)
5 / 11 TYR A 201
THR A 142
THR A 497
LEU A 476
ALA A 212
None
1.42A 6efnA-5ikzA:
5.8
6efnA-5ikzA:
16.85