SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5il5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 5il5 MLND
(Bacillus
velezensis) 		5 / 12 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.73A 1hshC-5il5A:
undetectable		 1hshC-5il5A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 5il5 MLND
(Bacillus
velezensis) 		5 / 12 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.66A 2b60A-5il5A:
undetectable		 2b60A-5il5A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 5il5 MLND
(Bacillus
velezensis) 		5 / 12 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.76A 2hs1A-5il5A:
undetectable		 2hs1A-5il5A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 5il5 MLND
(Bacillus
velezensis) 		5 / 12 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.74A 2hs1B-5il5A:
undetectable		 2hs1B-5il5A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 5il5 MLND
(Bacillus
velezensis) 		5 / 12 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.69A 2rkfA-5il5A:
undetectable		 2rkfA-5il5A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 5il5 MLND
(Bacillus
velezensis) 		5 / 12 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.74A 2rkgB-5il5A:
undetectable		 2rkgB-5il5A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 5il5 MLND
(Bacillus
velezensis) 		5 / 9 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.70A 3nu4B-5il5A:
undetectable		 3nu4B-5il5A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 5il5 MLND
(Bacillus
velezensis) 		5 / 10 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.66A 3s43B-5il5A:
undetectable		 3s43B-5il5A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 5il5 MLND
(Bacillus
velezensis) 		5 / 11 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.76A 3s45B-5il5A:
undetectable		 3s45B-5il5A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 5il5 MLND
(Bacillus
velezensis) 		4 / 6 GLY A1378
LEU A1500
TYR A1498
GLU A1509
 None
 0.80A 3w9tB-5il5A:
undetectable		 3w9tB-5il5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 5il5 MLND
(Bacillus
velezensis) 		4 / 6 GLY A1378
LEU A1500
TYR A1498
GLU A1509
 None
 0.80A 3w9tE-5il5A:
undetectable		 3w9tE-5il5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 5il5 MLND
(Bacillus
velezensis) 		4 / 6 GLY A1378
LEU A1500
TYR A1498
GLU A1509
 None
 0.81A 3w9tF-5il5A:
undetectable		 3w9tF-5il5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 5il5 MLND
(Bacillus
velezensis) 		5 / 12 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.65A 5e5jA-5il5A:
undetectable		 5e5jA-5il5A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 5il5 MLND
(Bacillus
velezensis) 		5 / 12 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.74A 5e5kB-5il5A:
undetectable		 5e5kB-5il5A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 5il5 MLND
(Bacillus
velezensis) 		5 / 12 GLY A1310
ALA A1309
ILE A1278
ILE A1303
ILE A1341
 None
 0.65A 5t8hA-5il5A:
undetectable		 5t8hA-5il5A:
15.09