SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5il7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 5il7 RAB FAMILY PROTEIN
(Chlorobaculum
tepidum) 		4 / 5 ILE A 207
ARG A 226
LEU A 224
ASN A 227
 None
 1.15A 1y0xX-5il7A:
undetectable		 1y0xX-5il7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5il7 RAB FAMILY PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 ASN A  95
LEU A  92
ASP A  93
SER A  72
 None
 1.31A 3lslA-5il7A:
undetectable
3lslD-5il7A:
undetectable		 3lslA-5il7A:
19.95
3lslD-5il7A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5il7 RAB FAMILY PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 SER A  72
ASN A  95
LEU A  92
ASP A  93
 None
 1.32A 3lslA-5il7A:
undetectable
3lslD-5il7A:
undetectable		 3lslA-5il7A:
19.95
3lslD-5il7A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5il7 RAB FAMILY PROTEIN
(Chlorobaculum
tepidum) 		5 / 9 LEU A 370
SER A 369
ILE A 342
ALA A 343
ALA A 324
 None
 1.27A 3mdtA-5il7A:
undetectable		 3mdtA-5il7A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 5il7 RAB FAMILY PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 ILE A 408
ILE A 364
LEU A 415
VAL A 423
 None
 0.87A 3ua5B-5il7A:
undetectable		 3ua5B-5il7A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5il7 RAB FAMILY PROTEIN
(Chlorobaculum
tepidum) 		4 / 6 LEU A 202
GLN A 245
LEU A 244
GLU A 243
 None
 1.00A 4nc3A-5il7A:
undetectable		 4nc3A-5il7A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 5il7 RAB FAMILY PROTEIN
(Chlorobaculum
tepidum) 		5 / 9 LEU A 415
ASN A 413
ILE A 342
PRO A 387
ILE A 383
 None
 1.13A 5kr2D-5il7A:
undetectable		 5kr2D-5il7A:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5il7 RAB FAMILY PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 375
THR A 374
GLY A 406
LEU A 386
PHE A 410
 None
 1.17A 5ybbA-5il7A:
undetectable		 5ybbA-5il7A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5il7 RAB FAMILY PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 LEU A  70
SER A  61
ILE A  56
VAL A   6
LEU A 106
 None
 1.39A 6djzB-5il7A:
undetectable		 6djzB-5il7A:
17.52