SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ila'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 5ila PROTEASE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 10 VAL A 131
VAL A 177
ALA A 168
ALA A 202
ILE A 195
 None
 1.11A 1likA-5ilaA:
undetectable		 1likA-5ilaA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 5ila PROTEASE DO-LIKE 9
(Arabidopsis
thaliana) 		4 / 8 THR A 166
LEU A 204
VAL A 192
THR A 175
 None
 1.08A 1o76B-5ilaA:
undetectable		 1o76B-5ilaA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 5ila PROTEASE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 12 ILE A 159
TRP A 212
GLY A 156
PHE A 157
ALA A 190
 None
 1.13A 1tlsB-5ilaA:
undetectable		 1tlsB-5ilaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ila PROTEASE DO-LIKE 9
(Arabidopsis
thaliana) 		3 / 3 THR A 197
GLU A 172
HIS A 174
 None
 0.73A 3g1uB-5ilaA:
undetectable		 3g1uB-5ilaA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 5ila PROTEASE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 9 ASP A 240
ILE A 158
PRO A 281
VAL A 233
ILE A 242
 None
 1.10A 3nu4A-5ilaA:
undetectable		 3nu4A-5ilaA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5ila PROTEASE DO-LIKE 9
(Arabidopsis
thaliana) 		4 / 7 GLY A 156
GLY A 279
VAL A 131
HIS A 169
 None
 0.92A 4c5nA-5ilaA:
undetectable		 4c5nA-5ilaA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 5ila PROTEASE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 12 GLY A 280
PRO A 281
VAL A 232
PHE A 157
LEU A 165
 None
 1.32A 5jo9A-5ilaA:
undetectable		 5jo9A-5ilaA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 5ila PROTEASE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 9 ASP A 240
ILE A 158
PRO A 281
VAL A 233
ILE A 242
 None
 1.15A 5kr0A-5ilaA:
undetectable		 5kr0A-5ilaA:
17.37