SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ilb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		3 / 3 ASN A 157
PHE A 147
VAL A 282
 None
 0.73A 1kijA-5ilbA:
undetectable		 1kijA-5ilbA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 9 GLY A 224
PRO A 265
GLY A 266
GLY A 229
GLY A 228
 None
 1.03A 1mxdA-5ilbA:
undetectable		 1mxdA-5ilbA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 11 GLY A 224
PRO A 265
GLY A 266
GLY A 229
GLY A 228
 None
 0.98A 1mxgA-5ilbA:
undetectable		 1mxgA-5ilbA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		6 / 11 ASP A 218
VAL A 220
ILE A 280
GLY A 281
ILE A 299
ILE A 259
 None
 1.27A 1n49C-5ilbA:
undetectable		 1n49C-5ilbA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2N27_A_4DYA205_1
(CALMODULIN)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 11 LEU A 489
THR A 450
ILE A 430
LEU A 496
VAL A 448
 None
 1.46A 2n27A-5ilbA:
undetectable		 2n27A-5ilbA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		6 / 10 ASP A 218
VAL A 220
ILE A 280
GLY A 281
ILE A 299
ILE A 259
 None
 1.37A 3ekpD-5ilbA:
undetectable		 3ekpD-5ilbA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 10 ILE A 259
VAL A 298
GLY A 256
LEU A 216
ARG A 386
 None
 1.26A 3elzC-5ilbA:
undetectable		 3elzC-5ilbA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		6 / 12 GLY A 266
ASN A 267
THR A 143
GLY A 144
SER A 145
GLY A 270
 None
 1.26A 3hlwB-5ilbA:
undetectable		 3hlwB-5ilbA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 10 ASP A 218
VAL A 220
ILE A 280
ILE A 299
ILE A 259
 None
 1.00A 3nu6A-5ilbA:
undetectable		 3nu6A-5ilbA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 10 ASP A 218
VAL A 220
ILE A 280
ILE A 299
ILE A 259
 None
 0.99A 3nujA-5ilbA:
undetectable		 3nujA-5ilbA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 12 HIS A 159
VAL A 187
ASP A 190
GLY A 266
SER A 268
 None
 0.78A 3sueC-5ilbA:
12.6		 3sueC-5ilbA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 12 HIS A 159
VAL A 187
ASP A 190
GLY A 266
SER A 268
 None
 0.83A 3sufD-5ilbA:
13.0		 3sufD-5ilbA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 12 ILE A 149
LEU A 213
VAL A 220
ILE A 191
ILE A 299
 None
 1.06A 3w67B-5ilbA:
undetectable		 3w67B-5ilbA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 11 ALA A 262
GLY A 266
GLY A 224
ILE A 263
ASN A 264
 None
 1.10A 4dcmA-5ilbA:
undetectable		 4dcmA-5ilbA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 12 ILE A 377
PHE A 393
ILE A 325
LEU A 323
ILE A 369
 None
 1.07A 4kjkA-5ilbA:
undetectable		 4kjkA-5ilbA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 11 ASP A 218
VAL A 220
ILE A 280
ILE A 299
ILE A 259
 None
 0.96A 4njtA-5ilbA:
undetectable		 4njtA-5ilbA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 11 ASP A 218
VAL A 220
ILE A 280
ILE A 299
ILE A 259
 None
 0.96A 4rvjA-5ilbA:
undetectable		 4rvjA-5ilbA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 11 ASP A 218
VAL A 220
ILE A 280
ILE A 299
ILE A 259
 None
 0.95A 4rvjC-5ilbA:
undetectable		 4rvjC-5ilbA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 11 VAL A 512
VAL A 490
ILE A 443
PHE A 442
LEU A 526
 None
 0.87A 5e4dB-5ilbA:
undetectable		 5e4dB-5ilbA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 11 VAL A 512
VAL A 490
VAL A 491
ILE A 443
PHE A 442
 None
 1.11A 5e4dB-5ilbA:
undetectable		 5e4dB-5ilbA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 12 GLY A 270
PRO A 271
VAL A 222
PHE A 147
LEU A 155
 None
 1.23A 5jo9A-5ilbA:
undetectable		 5jo9A-5ilbA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		4 / 5 ARG A 171
PHE A 147
LEU A 154
LEU A 115
 None
 1.28A 5veuH-5ilbA:
undetectable		 5veuH-5ilbA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 12 VAL A 383
LEU A 213
LEU A 255
ARG A 215
GLY A 388
 None
 1.15A 6b0lB-5ilbA:
undetectable		 6b0lB-5ilbA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 12 HIS A 159
VAL A 187
ASP A 190
GLY A 266
SER A 268
 None
 0.76A 6c2mC-5ilbA:
13.0		 6c2mC-5ilbA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9
(Arabidopsis
thaliana) 		5 / 12 ILE A 377
PHE A 393
ILE A 325
LEU A 323
ILE A 369
 None
 1.01A 7dfrA-5ilbA:
undetectable		 7dfrA-5ilbA:
15.45