SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ilg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 9 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.00A 1hpvB-5ilgA:
undetectable
1hpvB-5ilgA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 9 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.10A 1hxwA-5ilgA:
undetectable
1hxwA-5ilgA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.07A 1sduB-5ilgA:
undetectable
1sduB-5ilgA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
8 / 11 GLY A  12
ALA A  14
ASP A  37
LEU A  38
ASP A  63
VAL A  64
ALA A  91
VAL A 105
NAD  A 302 (-3.2A)
EDO  A 306 (-3.6A)
NAD  A 302 ( 2.9A)
NAD  A 302 (-4.2A)
NAD  A 302 (-3.6A)
NAD  A 302 (-3.6A)
NAD  A 302 (-3.9A)
NAD  A 302 (-3.9A)
0.35A 1uayA-5ilgA:
25.0
1uayA-5ilgA:
26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
8 / 10 GLY A  12
ALA A  14
ASP A  37
LEU A  38
ASP A  63
VAL A  64
ALA A  91
VAL A 105
NAD  A 302 (-3.2A)
EDO  A 306 (-3.6A)
NAD  A 302 ( 2.9A)
NAD  A 302 (-4.2A)
NAD  A 302 (-3.6A)
NAD  A 302 (-3.6A)
NAD  A 302 (-3.9A)
NAD  A 302 (-3.9A)
0.36A 1uayB-5ilgA:
25.1
1uayB-5ilgA:
26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 GLY A  12
GLY A  15
LEU A  38
ASP A  63
VAL A  64
NAD  A 302 (-3.2A)
NAD  A 302 (-3.6A)
NAD  A 302 (-4.2A)
NAD  A 302 (-3.6A)
NAD  A 302 (-3.6A)
0.84A 1zq9B-5ilgA:
4.3
1zq9B-5ilgA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 GLY A  15
ALA A  14
ASP A  40
VAL A  33
ILE A  35
NAD  A 302 (-3.6A)
EDO  A 306 (-3.6A)
None
None
None
0.85A 2bpxB-5ilgA:
undetectable
2bpxB-5ilgA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.05A 2f8gA-5ilgA:
undetectable
2f8gA-5ilgA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 7 GLY A   0
GLY A  29
ALA A  27
ALA A  28
HIS A  52
None
EDO  A 305 (-4.1A)
None
None
None
1.38A 2ha4B-5ilgA:
undetectable
2ha4B-5ilgA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 GLY A 108
ASN A  89
GLY A  92
ILE A  93
ILE A 157
None
None
NAD  A 302 ( 3.0A)
MG  A 301 ( 4.8A)
None
0.91A 2q64A-5ilgA:
undetectable
2q64A-5ilgA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 11 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.04A 2qhcA-5ilgA:
undetectable
2qhcA-5ilgA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.03A 2qhcB-5ilgA:
undetectable
2qhcB-5ilgA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
6 / 9 LEU A 118
ILE A 175
GLY A 122
GLY A 127
SER A 116
SER A 113
None
1.37A 2qmmA-5ilgA:
2.9
2qmmA-5ilgA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
6 / 11 LEU A 118
ILE A 175
GLY A 122
GLY A 127
SER A 116
SER A 113
None
1.37A 2qmmA-5ilgA:
2.7
2qmmB-5ilgA:
2.8
2qmmA-5ilgA:
25.09
2qmmB-5ilgA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 GLY A  15
ALA A  14
ASP A  40
VAL A  33
ILE A  35
NAD  A 302 (-3.6A)
EDO  A 306 (-3.6A)
None
None
None
0.79A 2r5pB-5ilgA:
undetectable
2r5pB-5ilgA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 GLY A  15
ALA A  14
ASP A  40
VAL A  33
ILE A  35
NAD  A 302 (-3.6A)
EDO  A 306 (-3.6A)
None
None
None
0.79A 2r5pD-5ilgA:
undetectable
2r5pD-5ilgA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
4 / 7 ASN A  89
SER A 113
TYR A  74
VAL A  64
None
None
None
NAD  A 302 (-3.6A)
1.17A 2uz2A-5ilgA:
undetectable
2uz2A-5ilgA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 9 ALA A   8
VAL A  88
VAL A  33
GLY A  13
ILE A 225
None
0.97A 2z0yA-5ilgA:
2.9
2z0yA-5ilgA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.01A 2z54A-5ilgA:
undetectable
2z54A-5ilgA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 ILE A  17
GLY A  18
ALA A  91
VAL A  90
ASN A  89
NAD  A 302 (-3.8A)
None
NAD  A 302 (-3.9A)
None
None
0.73A 3jb3A-5ilgA:
4.6
3jb3A-5ilgA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 GLY A  15
ALA A  14
ASP A  40
VAL A  33
ILE A  35
NAD  A 302 (-3.6A)
EDO  A 306 (-3.6A)
None
None
None
0.89A 3jvyA-5ilgA:
undetectable
3jvyA-5ilgA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.02A 3ndwA-5ilgA:
undetectable
3ndwA-5ilgA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 9 GLY A  15
ALA A  14
ASP A  40
VAL A  33
ILE A  35
NAD  A 302 (-3.6A)
EDO  A 306 (-3.6A)
None
None
None
0.86A 3oxvA-5ilgA:
undetectable
3oxvA-5ilgA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 10 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.01A 3oxwD-5ilgA:
undetectable
3oxwD-5ilgA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
4 / 6 ASP A  63
GLY A 109
VAL A 105
THR A  11
NAD  A 302 (-3.6A)
None
NAD  A 302 (-3.9A)
None
1.07A 3vqrA-5ilgA:
undetectable
3vqrA-5ilgA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
4 / 5 ASP A  63
GLY A 109
VAL A 105
THR A  11
NAD  A 302 (-3.6A)
None
NAD  A 302 (-3.9A)
None
1.09A 3vqrB-5ilgA:
2.6
3vqrB-5ilgA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
4 / 5 GLY A  12
ILE A  35
VAL A  88
SER A  22
NAD  A 302 (-3.2A)
None
None
None
1.16A 4d33A-5ilgA:
undetectable
4d33A-5ilgA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
4 / 5 GLY A  12
ILE A  35
VAL A  88
SER A  22
NAD  A 302 (-3.2A)
None
None
None
1.14A 4d33B-5ilgA:
undetectable
4d33B-5ilgA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
4 / 6 GLY A  12
ILE A  35
VAL A  88
SER A  22
NAD  A 302 (-3.2A)
None
None
None
1.13A 4d39B-5ilgA:
undetectable
4d39B-5ilgA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 9 VAL A   9
VAL A  70
ILE A  36
GLY A  13
SER A  22
None
1.19A 4fwdA-5ilgA:
2.4
4fwdA-5ilgA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 9 VAL A  88
VAL A  70
ILE A  36
GLY A  13
SER A  22
None
1.25A 4fwdA-5ilgA:
2.4
4fwdA-5ilgA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
4 / 7 ILE A 157
THR A 179
VAL A 105
ASP A  37
None
None
NAD  A 302 (-3.9A)
NAD  A 302 ( 2.9A)
1.15A 4iarA-5ilgA:
undetectable
4iarA-5ilgA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 9 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.16A 4ll3B-5ilgA:
undetectable
4ll3B-5ilgA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 11 GLY A  12
GLY A  13
ASP A  37
LEU A  38
ASP A  63
NAD  A 302 (-3.2A)
None
NAD  A 302 ( 2.9A)
NAD  A 302 (-4.2A)
NAD  A 302 (-3.6A)
0.61A 4pghA-5ilgA:
5.5
4pghA-5ilgA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
4 / 5 ILE A  17
VAL A  90
PHE A 160
CYH A 181
NAD  A 302 (-3.8A)
None
None
None
1.25A 4rzvA-5ilgA:
undetectable
4rzvA-5ilgA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 LEU A  38
ASP A  37
GLY A  12
ALA A  91
ILE A  93
NAD  A 302 (-4.2A)
NAD  A 302 ( 2.9A)
NAD  A 302 (-3.2A)
NAD  A 302 (-3.9A)
MG  A 301 ( 4.8A)
0.92A 4xdrA-5ilgA:
undetectable
4xdrA-5ilgA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
4 / 9 ILE A  17
TYR A 238
ILE A 209
LEU A 210
NAD  A 302 (-3.8A)
None
IPH  A 303 (-4.0A)
None
0.81A 5vkqB-5ilgA:
undetectable
5vkqC-5ilgA:
undetectable
5vkqB-5ilgA:
9.90
5vkqC-5ilgA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)
5ilg PHOTORECEPTOR
DEHYDROGENASE,
ISOFORM C

(Drosophila
melanogaster)
5 / 12 ASP A 232
ASP A  85
GLY A 174
VAL A 178
ILE A 131
None
1.06A 6difA-5ilgA:
undetectable
6difA-5ilgA:
15.09