SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ilq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5ilq ASPARTATE
CARBAMOYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 11 PHE A 114
ILE A  74
ALA A 365
LEU A 367
ALA A 117
 None
 1.30A 1jb0B-5ilqA:
undetectable		 1jb0B-5ilqA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 5ilq ASPARTATE
CARBAMOYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 6 LEU A 104
ILE A 128
CYH A 100
PHE A  99
 None
 0.95A 3ko0B-5ilqA:
undetectable		 3ko0B-5ilqA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 5ilq ASPARTATE
CARBAMOYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 6 LEU A 104
ILE A 128
CYH A 100
PHE A  99
 None
 0.96A 3ko0S-5ilqA:
undetectable		 3ko0S-5ilqA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5ilq ASPARTATE
CARBAMOYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 11 PHE A 114
ILE A  74
ALA A 365
LEU A 367
ALA A 117
 None
 1.30A 3pcqB-5ilqA:
undetectable		 3pcqB-5ilqA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 5ilq ASPARTATE
CARBAMOYLTRANSFERASE
(Plasmodium
falciparum) 		3 / 3 TYR A 137
TYR A 158
GLU A 143
 None
 0.91A 3pfgA-5ilqA:
5.8		 3pfgA-5ilqA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5ilq ASPARTATE
CARBAMOYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 8 LEU A 231
PHE A 218
VAL A 240
LEU A 214
 None
 0.78A 3uniB-5ilqA:
undetectable		 3uniB-5ilqA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 5ilq ASPARTATE
CARBAMOYLTRANSFERASE
(Plasmodium
falciparum) 		4 / 8 LYS A  58
ILE A 370
LEU A 366
ILE A 178
 None
 0.89A 4dtaB-5ilqA:
undetectable		 4dtaB-5ilqA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5ilq ASPARTATE
CARBAMOYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 12 VAL A 344
LEU A 321
ILE A 315
VAL A 245
LEU A 285
 None
 0.73A 4y8wC-5ilqA:
undetectable		 4y8wC-5ilqA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5ilq ASPARTATE
CARBAMOYLTRANSFERASE
(Plasmodium
falciparum) 		5 / 9 LEU A 331
HIS A 332
PRO A 333
VAL A 228
LEU A 231
 None
 1.41A 5o96E-5ilqA:
3.5
5o96F-5ilqA:
undetectable		 5o96E-5ilqA:
19.84
5o96F-5ilqA:
19.84