SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ilt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		3 / 3 VAL H 153
VAL H  34
TRP H 151
 None
 0.84A 1av2C-5iltH:
undetectable
1av2D-5iltH:
undetectable		 1av2C-5iltH:
6.45
1av2D-5iltH:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		3 / 3 VAL H 153
VAL H  34
TRP H 151
 None
 0.80A 1w5uC-5iltH:
undetectable
1w5uD-5iltH:
undetectable		 1w5uC-5iltH:
6.45
1w5uD-5iltH:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.01A 1zzrA-5iltL:
undetectable
1zzrB-5iltL:
undetectable		 1zzrA-5iltL:
19.95
1zzrB-5iltL:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.05A 1zzrA-5iltL:
undetectable
1zzrB-5iltL:
undetectable		 1zzrA-5iltL:
19.95
1zzrB-5iltL:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 0.99A 1zzuA-5iltL:
undetectable
1zzuB-5iltL:
undetectable		 1zzuA-5iltL:
19.95
1zzuB-5iltL:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.00A 1zzuA-5iltL:
undetectable
1zzuB-5iltL:
undetectable		 1zzuA-5iltL:
19.95
1zzuB-5iltL:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		3 / 3 VAL H  34
TRP H 151
VAL H 153
 None
 0.88A 2izqA-5iltH:
undetectable
2izqB-5iltH:
undetectable		 2izqA-5iltH:
6.45
2izqB-5iltH:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		5 / 12 VAL H 216
VAL H 235
SER H 233
ASN H 249
ASN H 208
 None
 1.43A 2y03A-5iltH:
undetectable		 2y03A-5iltH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		5 / 12 VAL H 216
VAL H 235
SER H 233
ASN H 249
ASN H 208
 None
 1.46A 2y03B-5iltH:
undetectable		 2y03B-5iltH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		5 / 7 SER L  34
ALA L  96
ALA L  91
ALA L  89
GLN H  97
 None
 1.48A 3a2qA-5iltL:
undetectable		 3a2qA-5iltL:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.03A 3dqrA-5iltL:
undetectable
3dqrB-5iltL:
undetectable		 3dqrA-5iltL:
19.86
3dqrB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.09A 3dqrA-5iltL:
undetectable
3dqrB-5iltL:
undetectable		 3dqrA-5iltL:
19.86
3dqrB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 0.96A 3jx2A-5iltL:
undetectable
3jx2B-5iltL:
undetectable		 3jx2A-5iltL:
19.86
3jx2B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.01A 3jx2A-5iltL:
undetectable
3jx2B-5iltL:
undetectable		 3jx2A-5iltL:
19.86
3jx2B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.02A 3jx3A-5iltL:
undetectable
3jx3B-5iltL:
undetectable		 3jx3A-5iltL:
19.86
3jx3B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.00A 3jx3A-5iltL:
undetectable
3jx3B-5iltL:
undetectable		 3jx3A-5iltL:
19.86
3jx3B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.05A 3jx4A-5iltL:
undetectable
3jx4B-5iltL:
undetectable		 3jx4A-5iltL:
19.86
3jx4B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.00A 3jx5A-5iltL:
undetectable
3jx5B-5iltL:
undetectable		 3jx5A-5iltL:
19.86
3jx5B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.03A 3jx5A-5iltL:
undetectable
3jx5B-5iltL:
undetectable		 3jx5A-5iltL:
19.86
3jx5B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 0.94A 3jx6A-5iltL:
undetectable
3jx6B-5iltL:
undetectable		 3jx6A-5iltL:
19.86
3jx6B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 0.99A 3jx6A-5iltL:
undetectable
3jx6B-5iltL:
undetectable		 3jx6A-5iltL:
19.86
3jx6B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		3 / 3 VAL H 153
VAL H  34
TRP H 151
 None
 0.83A 3l8lC-5iltH:
undetectable
3l8lD-5iltH:
undetectable		 3l8lC-5iltH:
6.45
3l8lD-5iltH:
5.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBR_A_ASDA129_1
(STEROID
DELTA-ISOMERASE)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		5 / 12 PHE H 219
VAL L 195
VAL L 144
PRO L 113
PHE L 139
 None
 1.39A 3nbrA-5iltH:
undetectable		 3nbrA-5iltH:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 0.95A 3nljA-5iltL:
undetectable
3nljB-5iltL:
undetectable		 3nljA-5iltL:
19.86
3nljB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.00A 3nljA-5iltL:
undetectable
3nljB-5iltL:
undetectable		 3nljA-5iltL:
19.86
3nljB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 0.97A 3nlpA-5iltL:
undetectable
3nlpB-5iltL:
undetectable		 3nlpA-5iltL:
19.86
3nlpB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.03A 3nlpA-5iltL:
undetectable
3nlpB-5iltL:
undetectable		 3nlpA-5iltL:
19.86
3nlpB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 8 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 0.96A 3nlqA-5iltL:
undetectable
3nlqB-5iltL:
undetectable		 3nlqA-5iltL:
19.86
3nlqB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.03A 3nlqA-5iltL:
undetectable
3nlqB-5iltL:
undetectable		 3nlqA-5iltL:
19.86
3nlqB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 0.95A 3nlrA-5iltL:
undetectable
3nlrB-5iltL:
undetectable		 3nlrA-5iltL:
19.86
3nlrB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 8 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.02A 3nlrA-5iltL:
undetectable
3nlrB-5iltL:
undetectable		 3nlrA-5iltL:
19.86
3nlrB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.00A 4cx3A-5iltL:
undetectable
4cx3B-5iltL:
undetectable		 4cx3A-5iltL:
19.86
4cx3B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.00A 4cx3A-5iltL:
undetectable
4cx3B-5iltL:
undetectable		 4cx3A-5iltL:
19.86
4cx3B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 1.03A 4cx4A-5iltL:
undetectable
4cx4B-5iltL:
undetectable		 4cx4A-5iltL:
19.86
4cx4B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.01A 4cx4A-5iltL:
undetectable
4cx4B-5iltL:
undetectable		 4cx4A-5iltL:
19.86
4cx4B-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		4 / 6 LYS H  13
LEU H  11
SER H  87
THR H  84
 None
 1.06A 4ikiB-5iltH:
undetectable		 4ikiB-5iltH:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		4 / 7 LYS H  13
LEU H  11
SER H  87
THR H  84
 None
 1.00A 4iklA-5iltH:
undetectable
4iklB-5iltH:
undetectable		 4iklA-5iltH:
16.91
4iklB-5iltH:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		5 / 10 VAL H 216
VAL H 235
SER H 233
ASN H 249
ASN H 208
 None
 1.49A 4ldoA-5iltH:
undetectable		 4ldoA-5iltH:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		5 / 12 VAL H 235
PHE H 246
VAL H 263
SER H 178
GLY H 192
 None
 1.32A 4mm6A-5iltH:
undetectable		 4mm6A-5iltH:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		3 / 3 GLY L  41
PRO L  40
ALA L  84
 None
 0.51A 4qn9B-5iltL:
undetectable		 4qn9B-5iltL:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 0.96A 5addA-5iltL:
undetectable
5addB-5iltL:
undetectable		 5addA-5iltL:
19.86
5addB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 0.98A 5adeA-5iltL:
undetectable
5adeB-5iltL:
undetectable		 5adeA-5iltL:
19.86
5adeB-5iltL:
19.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 8 SER L  34
TYR L  36
TYR H 149
PHE L  98
 None
 0.87A 5albL-5iltL:
19.5		 5albL-5iltL:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 8 SER L  34
TYR L  36
SER L  94
PHE L  98
 None
 0.64A 5alcL-5iltL:
26.0		 5alcL-5iltL:
67.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		4 / 6 GLY H 239
THR H 241
SER H 186
VAL H 189
 None
 1.05A 5ewuA-5iltH:
undetectable		 5ewuA-5iltH:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		4 / 6 GLY H 239
THR H 241
SER H 186
VAL H 189
 None
 0.84A 5ewuB-5iltH:
undetectable		 5ewuB-5iltH:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 VAL L 106
ARG L  61
VAL L  19
GLU L  83
 None
 0.99A 5g0pA-5iltL:
undetectable
5g0pB-5iltL:
undetectable		 5g0pA-5iltL:
19.86
5g0pB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 7 GLU L  83
VAL L 106
ARG L  61
VAL L  19
 None
 1.02A 5g0pA-5iltL:
undetectable
5g0pB-5iltL:
undetectable		 5g0pA-5iltL:
19.86
5g0pB-5iltL:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 8 THR L  74
SER L  63
THR L  72
SER L  65
 None
 1.03A 5l4eA-5iltL:
undetectable
5l4eB-5iltL:
undetectable
5l4eC-5iltL:
undetectable
5l4eD-5iltL:
undetectable
5l4eE-5iltL:
undetectable		 5l4eA-5iltL:
23.13
5l4eB-5iltL:
23.13
5l4eC-5iltL:
23.13
5l4eD-5iltL:
23.13
5l4eE-5iltL:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 5ilt BOVINE FAB A01 LIGHT
CHAIN
(Bos
taurus) 		4 / 6 LEU L 132
ALA L 130
LEU L 178
THR L 181
 None
 1.09A 5l4iB-5iltL:
4.1		 5l4iB-5iltL:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		4 / 7 LEU H 142
ILE H 110
THR H 119
TYR H 147
 None
 0.99A 5zsfA-5iltH:
undetectable
5zsfB-5iltH:
undetectable		 5zsfA-5iltH:
16.29
5zsfB-5iltH:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		5 / 11 VAL H 259
THR H 257
VAL H 263
ALA H 171
VAL H 205
 None
 1.08A 6dryA-5iltH:
undetectable		 6dryA-5iltH:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5ilt BOVINE FAB A01 HEAVY
CHAIN
(Bos
taurus) 		5 / 12 VAL H 216
VAL H 235
SER H 233
ASN H 249
ASN H 208
 None
 1.44A 6h7mB-5iltH:
undetectable		 6h7mB-5iltH:
15.00