SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5im3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY5_A_ACTA600_0
(RIBONUCLEASE A)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 560
VAL A 450
ASN A 482
THR A 483
 None
 1.36A 1dy5A-5im3A:
undetectable		 1dy5A-5im3A:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 307
PHE A 322
PHE A 295
THR A 779
 None
 1.25A 1ea1A-5im3A:
undetectable		 1ea1A-5im3A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 467
PRO A 506
VAL A 426
GLY A 425
 None
 1.03A 1hrkA-5im3A:
undetectable		 1hrkA-5im3A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 121
ARG A 125
TYR A 124
GLU A 106
 DTP  A1002 ( 3.6A)
None
DTP  A1002 (-3.4A)
None
 1.32A 1nx9A-5im3A:
undetectable		 1nx9A-5im3A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 121
ARG A 125
TYR A 124
GLU A 106
 DTP  A1002 ( 3.6A)
None
DTP  A1002 (-3.4A)
None
 1.33A 1nx9B-5im3A:
undetectable		 1nx9B-5im3A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 121
ARG A 125
TYR A 124
GLU A 106
 DTP  A1002 ( 3.6A)
None
DTP  A1002 (-3.4A)
None
 1.32A 1nx9C-5im3A:
undetectable		 1nx9C-5im3A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 121
ARG A 125
TYR A 124
GLU A 106
 DTP  A1002 ( 3.6A)
None
DTP  A1002 (-3.4A)
None
 1.32A 1nx9D-5im3A:
undetectable		 1nx9D-5im3A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 401
ASN A 585
SER A 606
GLU A 589
VAL A 450
 None
 1.44A 1qu3A-5im3A:
undetectable		 1qu3A-5im3A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 10 ARG A 632
GLY A 659
ILE A 697
ILE A 607
ALA A 699
 None
 0.98A 1sh9B-5im3A:
undetectable		 1sh9B-5im3A:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 7 ASP A 489
TYR A 516
ASP A 567
LYS A 493
 None
 1.46A 1t03A-5im3A:
undetectable		 1t03A-5im3A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 395
ASN A 392
ALA A 437
LEU A 586
THR A 376
 None
 1.22A 1ya3B-5im3A:
undetectable		 1ya3B-5im3A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 236
VAL A 241
GLY A 240
LEU A 318
ALA A 257
 None
 1.02A 2egvA-5im3A:
undetectable		 2egvA-5im3A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 395
ASN A 392
ALA A 437
LEU A 586
THR A 376
 None
 1.28A 2oaxB-5im3A:
undetectable		 2oaxB-5im3A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 395
ASN A 392
ALA A 437
LEU A 586
THR A 376
 None
 1.26A 2oaxC-5im3A:
undetectable		 2oaxC-5im3A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 467
PRO A 506
VAL A 426
GLY A 425
 None
 0.99A 2po5A-5im3A:
undetectable		 2po5A-5im3A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 8 ASP A 686
GLU A 728
LEU A 744
SER A 864
 None
 1.03A 2q0iA-5im3A:
undetectable		 2q0iA-5im3A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 7 SER A 700
LEU A 723
ILE A 766
GLY A 721
 None
 1.00A 2v0mC-5im3A:
undetectable		 2v0mC-5im3A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 861
GLN A 867
ARG A 572
 None
 0.80A 2w3bB-5im3A:
undetectable		 2w3bB-5im3A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 SER A 356
THR A 774
PHE A 295
 None
 0.56A 2x91A-5im3A:
2.1		 2x91A-5im3A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 374
GLN A 872
ILE A 590
SER A 651
 None
 1.16A 2xz5B-5im3A:
undetectable
2xz5E-5im3A:
undetectable		 2xz5B-5im3A:
11.85
2xz5E-5im3A:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 459
ILE A 487
MET A 492
PHE A 491
VAL A 542
 None
 1.04A 2ygnA-5im3A:
undetectable		 2ygnA-5im3A:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 5 ASN A 603
THR A 712
SER A 764
SER A 573
 None
 1.09A 3hlwB-5im3A:
undetectable		 3hlwB-5im3A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 375
VAL A 581
THR A 902
ALA A 873
THR A 588
 None
 1.28A 3mdtA-5im3A:
undetectable		 3mdtA-5im3A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 248
HIS A 247
HIS A 289
 None
 0.85A 3mihA-5im3A:
undetectable		 3mihA-5im3A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 289
HIS A 248
HIS A 247
 None
 0.85A 3mihA-5im3A:
undetectable		 3mihA-5im3A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 795
ARG A 210
ASP A 305
 None
 1.23A 3o7wA-5im3A:
undetectable		 3o7wA-5im3A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 876
ALA A 873
ILE A 590
GLY A 661
ILE A 662
 None
 1.01A 3ogpA-5im3A:
undetectable		 3ogpA-5im3A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 5 ALA A 339
GLU A 338
ALA A 331
MET A 324
 None
 1.15A 3r9tC-5im3A:
2.2		 3r9tC-5im3A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 299
THR A 302
ASN A 777
 None
 0.61A 3v4tD-5im3A:
1.4		 3v4tD-5im3A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 693
ARG A 754
ILE A 697
GLU A 690
 None
 1.28A 4cx7A-5im3A:
undetectable
4cx7B-5im3A:
undetectable		 4cx7A-5im3A:
19.18
4cx7B-5im3A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 334
LEU A 347
LEU A 703
THR A 629
ARG A 656
 None
 1.11A 4hytA-5im3A:
undetectable		 4hytA-5im3A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 334
LEU A 347
LEU A 703
THR A 629
ARG A 656
 None
 1.11A 4hytC-5im3A:
1.5		 4hytC-5im3A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 908
LEU A 888
TYR A 892
LEU A 906
 None
 0.93A 4iomA-5im3A:
3.0		 4iomA-5im3A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 4 TYR A 307
THR A 359
VAL A 326
ILE A 775
 None
 1.30A 4jx1F-5im3A:
undetectable		 4jx1F-5im3A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 6 ASP A 514
TYR A 516
HIS A 582
THR A 594
 None
 1.33A 4paeA-5im3A:
0.0		 4paeA-5im3A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 176
HIS A 247
HIS A 248
GLU A 290
 None
 0.90A 4pahA-5im3A:
undetectable		 4pahA-5im3A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 776
GLY A 664
ILE A 870
ALA A 768
GLY A 661
 None
 0.98A 4r29D-5im3A:
undetectable		 4r29D-5im3A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 616
ASP A 615
ILE A 613
ALA A 668
HIS A 673
 None
 1.41A 4wh5A-5im3A:
undetectable		 4wh5A-5im3A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 375
ALA A 768
GLN A 872
ILE A 870
PRO A 657
 None
 1.40A 5ewjC-5im3A:
undetectable
5ewjD-5im3A:
undetectable		 5ewjC-5im3A:
18.55
5ewjD-5im3A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 105
ALA A 108
GLN A  81
VAL A  82
 None
 1.03A 5i8fA-5im3A:
undetectable		 5i8fA-5im3A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 330
TYR A 353
SER A 356
 None
 0.89A 5iktA-5im3A:
0.0		 5iktA-5im3A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 9 ASN A 652
ASP A 635
GLY A 659
THR A 359
PRO A 358
 None
 1.25A 5kr2C-5im3A:
undetectable		 5kr2C-5im3A:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 669
ALA A 681
PHE A 684
ILE A 785
LEU A 900
 None
 1.35A 5ljbA-5im3A:
undetectable		 5ljbA-5im3A:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 THR A 774
THR A 302
ARG A 306
 None
 1.06A 5wm2A-5im3A:
2.2		 5wm2A-5im3A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 254
ASP A 288
GLN A 320
 None
 0.94A 6g1pA-5im3A:
undetectable		 6g1pA-5im3A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 637
ASN A 641
ASN A 362
PRO A 368
 None
 1.22A 6h7uA-5im3A:
undetectable		 6h7uA-5im3A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 6 SER A 355
ARG A 325
ALA A 363
THR A 365
 None
 1.12A 6ma6A-5im3A:
undetectable		 6ma6A-5im3A:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 ILE A 859
THR A 856
PRO A 787
 None
 0.60A 6ncsA-5im3A:
3.4		 6ncsA-5im3A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 176
HIS A 247
HIS A 248
GLU A 290
 None
 0.95A 6pahA-5im3A:
undetectable		 6pahA-5im3A:
16.28