SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5im6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT
(Burkholderia
thailandensis) 		5 / 8 PHE A 160
ILE A 110
LEU A 176
LEU A 106
GLU A 107
 None
 1.34A 1eupA-5im6A:
undetectable		 1eupA-5im6A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT
(Burkholderia
thailandensis) 		5 / 12 GLY A 117
LEU A  49
LEU A  62
VAL A  58
ALA A 169
 None
 1.12A 1gseA-5im6A:
undetectable		 1gseA-5im6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT
(Burkholderia
thailandensis) 		5 / 12 GLY A 117
LEU A  49
LEU A  62
VAL A  58
ALA A 169
 None
 1.06A 1gseB-5im6A:
undetectable		 1gseB-5im6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT
(Burkholderia
thailandensis) 		4 / 7 PRO A  55
ALA A 169
LEU A 166
ALA A 115
 None
 0.87A 2vcvA-5im6A:
undetectable		 2vcvA-5im6A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT
(Burkholderia
thailandensis) 		4 / 7 PRO A  55
ALA A 169
LEU A 166
ALA A 115
 None
 0.86A 2vcvG-5im6A:
undetectable		 2vcvG-5im6A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT
(Burkholderia
thailandensis) 		4 / 6 LEU A 138
ILE A 135
LEU A  76
GLU A  75
 None
 0.96A 4w5nA-5im6A:
undetectable		 4w5nA-5im6A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5im6 DESIGNED
SELF-ASSEMBLING
ICOSAHEDRAL CAGE
I32-28 TRIMERIC
SUBUNIT
(Burkholderia
thailandensis) 		5 / 12 CYH A 124
ILE A  65
LEU A  54
LEU A 166
LEU A 162
 None
 1.20A 4xumA-5im6A:
undetectable		 4xumA-5im6A:
18.80