SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5in7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		3 / 3 ASP A 167
PHE A 138
VAL A 153
 None
 0.75A 1kijB-5in7A:
undetectable		 1kijB-5in7A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		5 / 12 ASP A 167
LEU A 164
ILE A 149
SER A 205
PHE A 138
 None
 1.33A 1xmuA-5in7A:
undetectable		 1xmuA-5in7A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_A_CIOA603_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		5 / 12 ASP A 167
LEU A 164
ILE A 149
SER A 205
PHE A 138
 None
 1.38A 1xomA-5in7A:
undetectable		 1xomA-5in7A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		5 / 12 ASP A 167
LEU A 164
ILE A 149
SER A 205
PHE A 138
 None
 1.35A 1xoqB-5in7A:
undetectable		 1xoqB-5in7A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		4 / 5 VAL A 182
GLY A 181
TYR A 184
ASP A 211
 None
 1.24A 3w9tA-5in7A:
undetectable		 3w9tA-5in7A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		4 / 5 VAL A 182
GLY A 181
TYR A 184
ASP A 211
 None
 1.24A 3w9tB-5in7A:
undetectable		 3w9tB-5in7A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		4 / 5 VAL A 182
GLY A 181
TYR A 184
ASP A 211
 None
 1.24A 3w9tC-5in7A:
undetectable		 3w9tC-5in7A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		4 / 5 VAL A 182
GLY A 181
TYR A 184
ASP A 211
 None
 1.24A 3w9tD-5in7A:
undetectable		 3w9tD-5in7A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		4 / 5 VAL A 182
GLY A 181
TYR A 184
ASP A 211
 None
 1.23A 3w9tE-5in7A:
undetectable		 3w9tE-5in7A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		4 / 5 VAL A 182
GLY A 181
TYR A 184
ASP A 211
 None
 1.24A 3w9tF-5in7A:
undetectable		 3w9tF-5in7A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 5in7 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		4 / 5 VAL A 182
GLY A 181
TYR A 184
ASP A 211
 None
 1.23A 3w9tG-5in7A:
undetectable		 3w9tG-5in7A:
18.02