SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5inf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 6 GLY A  87
TYR A  84
ALA A  35
GLU A  30
 None
 0.93A 1dmaB-5infA:
undetectable		 1dmaB-5infA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 HIS A  73
GLY A  85
ASP A  68
VAL A  71
ARG A 146
 None
 1.32A 1n2xA-5infA:
undetectable		 1n2xA-5infA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 11 GLY A 431
ALA A 432
ASP A 433
ILE A 410
ILE A 361
 None
 0.80A 1sdvB-5infA:
undetectable		 1sdvB-5infA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 LEU A 327
PHE A 363
GLN A 173
PRO A 260
VAL A 252
 None
 1.33A 1u72A-5infA:
undetectable		 1u72A-5infA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 7 LEU A  49
ILE A 249
ILE A 139
ASP A  56
 None
 0.85A 1uwjA-5infA:
undetectable		 1uwjA-5infA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_1
(PROTEASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 11 GLY A 431
ALA A 432
ASP A 433
ILE A 410
ILE A 361
 None
 0.95A 2nnpA-5infA:
undetectable		 2nnpA-5infA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 5 LEU A 398
LEU A 349
LEU A 345
MET A 425
 None
 1.12A 2oaxF-5infA:
undetectable		 2oaxF-5infA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 GLY A 431
ALA A 432
ASP A 433
ILE A 410
ILE A 361
 None
 0.85A 2q5kB-5infA:
undetectable		 2q5kB-5infA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 GLY A 431
ALA A 432
ASP A 433
ILE A 410
ILE A 361
 None
 0.84A 2r5pD-5infA:
undetectable		 2r5pD-5infA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 11 GLY A 431
ALA A 432
ASP A 433
ILE A 410
ILE A 361
 None
 0.88A 2r5qB-5infA:
undetectable		 2r5qB-5infA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 10 GLY A 431
ALA A 432
ASP A 433
ILE A 410
ILE A 361
 None
 0.88A 2r5qD-5infA:
undetectable		 2r5qD-5infA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 8 GLY A 236
HIS A 231
MET A 197
GLU A 233
 None
 0.94A 2x0pA-5infA:
undetectable		 2x0pA-5infA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 11 SER A 185
SER A 142
TYR A 203
ALA A 182
GLY A 183
 None
 1.43A 2xf3B-5infA:
undetectable		 2xf3B-5infA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 7 PRO A 382
ILE A 391
PRO A 378
GLY A 379
 None
 0.97A 2y7kA-5infA:
undetectable		 2y7kA-5infA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 6 VAL A  33
VAL A  32
ARG A  52
ARG A  72
 None
 1.06A 3bjwF-5infA:
undetectable		 3bjwF-5infA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_2
(RENIN)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 4 VAL A 122
TYR A 157
PRO A 189
PHE A 103
 None
 1.43A 3d91B-5infA:
undetectable		 3d91B-5infA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 10 GLY A 431
ALA A 432
ASP A 433
ILE A 410
ILE A 361
 None
 0.95A 3el9B-5infA:
undetectable		 3el9B-5infA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 7 THR A 411
VAL A 371
THR A 373
VAL A 338
 None
 0.58A 3em0B-5infA:
undetectable		 3em0B-5infA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 6 SER A 188
PHE A 103
HIS A 105
ASN A 140
 None
 1.18A 3lskB-5infA:
undetectable		 3lskB-5infA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 6 SER A 188
PHE A 103
HIS A 105
ASN A 140
 None
 1.25A 3lskD-5infA:
1.3		 3lskD-5infA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA206_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 4 ASP A 106
ARG A  52
THR A  50
ALA A  39
 None
 1.41A 3mbgA-5infA:
0.0		 3mbgA-5infA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 7 GLY A 431
ALA A 432
ASP A 433
ILE A 361
 None
 0.64A 3t3cA-5infA:
undetectable		 3t3cA-5infA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		3 / 3 PHE A 128
CYH A 101
HIS A  92
 None
 1.21A 3u9fF-5infA:
undetectable		 3u9fF-5infA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		3 / 3 PHE A 128
CYH A 101
HIS A  92
 None
 1.19A 3u9fG-5infA:
undetectable		 3u9fG-5infA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		3 / 3 PHE A 128
CYH A 101
HIS A  92
 None
 1.28A 3u9fL-5infA:
undetectable		 3u9fL-5infA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		3 / 3 PHE A 128
CYH A 101
HIS A  92
 None
 1.23A 3u9fS-5infA:
undetectable		 3u9fS-5infA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 4 LEU A 349
ILE A 413
TYR A 418
TYR A 402
 None
 1.32A 3vt7A-5infA:
undetectable		 3vt7A-5infA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		3 / 3 ASP A  86
GLU A 116
GLY A 115
 None
 0.56A 3w9tA-5infA:
undetectable		 3w9tA-5infA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 LYS A  48
ASP A 106
HIS A 105
GLY A 111
ASP A 141
 None
 0.87A 4blvB-5infA:
undetectable		 4blvB-5infA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 LEU A 512
VAL A 371
ALA A 336
SER A 334
LEU A 327
 None
 1.14A 4coxD-5infA:
undetectable		 4coxD-5infA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 7 GLY A  87
TYR A  84
ALA A  35
GLU A  30
 None
 0.86A 4hyfA-5infA:
undetectable		 4hyfA-5infA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 8 GLY A  87
TYR A  84
ALA A  35
GLU A  30
 None
 0.92A 4hyfB-5infA:
undetectable		 4hyfB-5infA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 8 GLY A  87
TYR A  84
ALA A  35
GLU A  30
 None
 0.84A 4hyfC-5infA:
undetectable		 4hyfC-5infA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 5 GLY A 119
SER A 120
ALA A 117
GLU A 116
 None
 1.02A 4m93B-5infA:
undetectable
4m93C-5infA:
undetectable		 4m93B-5infA:
17.93
4m93C-5infA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJQ_A_27RA401_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 5 ARG A 415
TYR A 297
PRO A 342
VAL A 348
 None
 1.42A 4mjqA-5infA:
undetectable		 4mjqA-5infA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		3 / 3 SER A  63
ASP A  60
GLN A 253
 None
 0.87A 4oltA-5infA:
0.6
4oltB-5infA:
undetectable		 4oltA-5infA:
19.05
4oltB-5infA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		3 / 3 GLN A 253
SER A  63
ASP A  60
 None
 0.95A 4qwpA-5infA:
undetectable
4qwpB-5infA:
undetectable		 4qwpA-5infA:
19.05
4qwpB-5infA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 LEU A 512
VAL A 371
ALA A 336
SER A 334
LEU A 327
 None
 1.10A 4rrxA-5infA:
undetectable		 4rrxA-5infA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 LEU A 512
VAL A 371
ALA A 336
SER A 334
LEU A 327
 None
 1.12A 4rrxB-5infA:
undetectable		 4rrxB-5infA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 7 TYR A 380
GLY A 395
SER A 354
LEU A 398
 None
 1.00A 5bphB-5infA:
undetectable		 5bphB-5infA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 6 TYR A 487
ILE A 413
VAL A 498
ALA A 437
 None
 0.84A 5cu6A-5infA:
undetectable		 5cu6A-5infA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 7 GLY A 431
SER A 427
GLY A 426
ALA A 403
 None
 0.82A 5e26C-5infA:
undetectable
5e26D-5infA:
undetectable		 5e26C-5infA:
21.64
5e26D-5infA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 7 TYR A 258
PHE A 360
ILE A 315
LEU A 307
 None
 0.99A 5esmA-5infA:
undetectable		 5esmA-5infA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 ASP A 298
ALA A 339
LYS A 356
GLU A 314
VAL A 337
 None
 1.16A 5hw4A-5infA:
undetectable		 5hw4A-5infA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 ASP A 298
ALA A 339
LYS A 356
GLU A 314
VAL A 337
 None
 1.15A 5hw4C-5infA:
undetectable		 5hw4C-5infA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 LEU A 512
VAL A 371
ALA A 336
SER A 334
LEU A 327
 None
 1.08A 5ikqA-5infA:
undetectable		 5ikqA-5infA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 6 GLU A 442
TYR A 418
GLY A 419
GLY A 420
 None
 0.98A 5x7pB-5infA:
undetectable		 5x7pB-5infA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9A_A_AR3A201_1
(PEPTIDYL-TRNA
HYDROLASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 6 ALA A 521
GLN A 520
LYS A 518
ASP A 365
 None
 0.97A 5y9aA-5infA:
2.4		 5y9aA-5infA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 11 PHE A 118
GLY A 112
MET A 114
ASN A 140
GLY A 143
 None
 1.26A 5yjsA-5infA:
undetectable		 5yjsA-5infA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 GLY A 431
ALA A 432
ASP A 433
ILE A 410
ILE A 361
 None
 0.86A 6dj1B-5infA:
undetectable		 6dj1B-5infA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		5 / 12 GLY A 431
ALA A 432
ASP A 433
ILE A 410
ILE A 361
 None
 0.88A 6dj2B-5infA:
undetectable		 6dj2B-5infA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 7 GLN A 386
GLY A 421
GLY A 379
VAL A 377
 None
 0.78A 6ekzA-5infA:
undetectable		 6ekzA-5infA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5inf CARBOXYL TRANSFERASE
(Streptomyces
ambofaciens) 		4 / 6 ASP A  56
ARG A  52
GLU A  36
GLU A  69
 None
 1.45A 6mn5D-5infA:
undetectable		 6mn5D-5infA:
10.75