SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5inr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 11 ASP A 123
LEU A 119
GLY A 120
TYR A  53
VAL A  60
 None
 1.48A 1axwB-5inrA:
undetectable		 1axwB-5inrA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 12 PHE A 233
GLY A 172
GLY A 173
LEU A 146
LEU A 211
 None
 0.85A 1ya4B-5inrA:
undetectable		 1ya4B-5inrA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 12 PHE A 233
GLY A 172
GLY A 173
LEU A 146
LEU A 211
 None
 0.84A 1ya4C-5inrA:
undetectable		 1ya4C-5inrA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		3 / 3 ASN A  45
ARG A  70
ASP A 426
 None
EDO  A 510 (-3.8A)
None
 0.83A 2qe6A-5inrA:
undetectable		 2qe6A-5inrA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		3 / 3 ASN A  45
ARG A  70
ASP A 426
 None
EDO  A 510 (-3.8A)
None
 0.87A 2qe6B-5inrA:
undetectable		 2qe6B-5inrA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 7 SER A  27
ILE A 324
ILE A  12
GLY A  22
 None
 0.93A 2v0mB-5inrA:
undetectable		 2v0mB-5inrA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZS9_A_PAUA603_0
(PANTOTHENATE KINASE)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 6 VAL A 396
ASP A 298
HIS A 291
ASN A 400
 None
 1.09A 2zs9A-5inrA:
undetectable		 2zs9A-5inrA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HTH_B_PRLB201_0
(EBRA REPRESSOR)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 9 VAL A 132
LEU A 142
TYR A  53
LEU A 124
ASP A 123
 None
 1.40A 3hthB-5inrA:
0.4		 3hthB-5inrA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 12 ILE A 171
GLY A 172
GLY A 173
PRO A 154
VAL A 108
 None
 0.81A 3jb2A-5inrA:
undetectable		 3jb2A-5inrA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 12 SER A  58
VAL A  60
SER A  55
THR A 151
VAL A 127
 None
 1.25A 3mbhC-5inrA:
undetectable		 3mbhC-5inrA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 6 TYR A 365
PHE A 354
PRO A 362
LEU A 438
 None
 1.12A 3tgvB-5inrA:
undetectable		 3tgvB-5inrA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 6 TYR A 365
PHE A 354
PRO A 362
LEU A 438
 None
 1.19A 3tgvD-5inrA:
undetectable		 3tgvD-5inrA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 6 GLY A 337
ILE A 338
GLN A 326
VAL A 331
 None
 0.96A 4d39B-5inrA:
undetectable		 4d39B-5inrA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 8 ASN A 349
ALA A 342
TYR A 410
TYR A 365
 None
 1.21A 4ijiF-5inrA:
undetectable		 4ijiF-5inrA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		3 / 3 ASN A 228
ASP A 268
ASP A 240
 None
 0.73A 4obwD-5inrA:
undetectable		 4obwD-5inrA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 12 TYR A 227
PHE A 233
HIS A 175
ASP A 112
GLY A 172
 None
 1.14A 4qa0A-5inrA:
undetectable		 4qa0A-5inrA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 11 TYR A 227
PHE A 233
HIS A 175
ASP A 112
GLY A 172
 None
 1.16A 4qa0B-5inrA:
undetectable		 4qa0B-5inrA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 12 TYR A 227
PHE A 233
HIS A 175
ASP A 112
GLY A 172
 None
 1.11A 4qa2B-5inrA:
undetectable		 4qa2B-5inrA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 6 LEU A 438
LEU A 341
PHE A  41
THR A 361
 None
 1.04A 4udaA-5inrA:
undetectable		 4udaA-5inrA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		3 / 3 VAL A  43
ALA A 356
PHE A  41
 None
EDO  A 510 (-3.8A)
None
 0.86A 4z4iA-5inrA:
undetectable		 4z4iA-5inrA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 12 GLY A 138
SER A 158
ILE A 157
VAL A 128
VAL A 125
 None
 1.11A 5dpdB-5inrA:
undetectable		 5dpdB-5inrA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		3 / 3 VAL A  43
ALA A 356
PHE A  41
 None
EDO  A 510 (-3.8A)
None
 0.86A 5js1A-5inrA:
undetectable		 5js1A-5inrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		3 / 3 SER A  97
ALA A  95
VAL A  94
 None
 0.53A 5xiwC-5inrA:
undetectable		 5xiwC-5inrA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		5 / 12 LEU A 214
LEU A 211
GLY A 172
GLY A 234
ARG A 230
 None
None
None
EDO  A 509 (-4.2A)
None
 0.84A 6ce2B-5inrA:
undetectable		 6ce2B-5inrA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 6 ARG A 318
ILE A 314
ASN A  29
ASP A  31
 PRO  A 502 (-3.7A)
None
None
None
 1.23A 6dhbA-5inrA:
undetectable		 6dhbA-5inrA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 6 ASN A 244
ASP A 240
SER A 235
ARG A 230
 None
 1.15A 6dwdA-5inrA:
undetectable
6dwdC-5inrA:
undetectable		 6dwdA-5inrA:
22.32
6dwdC-5inrA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 6 ASP A 123
TYR A 152
GLU A 153
CYH A   9
 None
None
None
ALA  A 501 (-3.3A)
 1.24A 6mn5A-5inrA:
undetectable		 6mn5A-5inrA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 7 ASP A 123
TYR A 152
GLU A 153
CYH A   9
 None
None
None
ALA  A 501 (-3.3A)
 1.20A 6mn5B-5inrA:
undetectable		 6mn5B-5inrA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 7 ASP A 123
TYR A 152
GLU A 153
CYH A   9
 None
None
None
ALA  A 501 (-3.3A)
 1.30A 6mn5E-5inrA:
undetectable		 6mn5E-5inrA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_F_LLLF301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5inr DIPEPTIDASE
(Lactobacillus
farciminis) 		4 / 5 ASP A 123
TYR A 152
GLU A 153
CYH A   9
 None
None
None
ALA  A 501 (-3.3A)
 1.27A 6mn5F-5inrA:
0.0		 6mn5F-5inrA:
11.44