SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5inw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 LEU A 359
LEU A  91
VAL A  95
ALA A 115
PHE A 106
 None
 1.04A 1dfoA-5inwA:
undetectable		 1dfoA-5inwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 LEU A 359
LEU A  91
VAL A  95
ALA A 115
PHE A 106
 None
 1.05A 1dfoB-5inwA:
undetectable		 1dfoB-5inwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 LEU A 359
LEU A  91
VAL A  95
ALA A 115
PHE A 106
 None
 1.04A 1dfoC-5inwA:
undetectable		 1dfoC-5inwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 LEU A 359
LEU A  91
VAL A  95
ALA A 115
PHE A 106
 None
 1.05A 1dfoD-5inwA:
undetectable		 1dfoD-5inwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 LEU A 359
LEU A  91
VAL A  95
ALA A 115
PHE A 106
 None
 1.03A 1eqbA-5inwA:
undetectable		 1eqbA-5inwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 LEU A 359
LEU A  91
VAL A  95
ALA A 115
PHE A 106
 None
 1.03A 1eqbB-5inwA:
undetectable		 1eqbB-5inwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 LEU A 359
LEU A  91
VAL A  95
ALA A 115
PHE A 106
 None
 1.03A 1eqbC-5inwA:
undetectable		 1eqbC-5inwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 LEU A 359
LEU A  91
VAL A  95
ALA A 115
PHE A 106
 None
 1.03A 1eqbD-5inwA:
undetectable		 1eqbD-5inwA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 11 SER A 364
ALA A 134
VAL A 119
ALA A 115
LEU A  87
 None
 1.03A 1jinA-5inwA:
undetectable		 1jinA-5inwA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 11 SER A 369
ALA A 134
VAL A 119
ALA A 115
LEU A  87
 None
 1.08A 1jinA-5inwA:
undetectable		 1jinA-5inwA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		4 / 8 TYR A 161
PHE A 247
GLY A 171
THR A 411
 None
 0.89A 1ykiA-5inwA:
undetectable
1ykiB-5inwA:
undetectable		 1ykiA-5inwA:
21.88
1ykiB-5inwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		4 / 8 THR A 411
TYR A 161
PHE A 247
GLY A 171
 None
 0.85A 1ykiA-5inwA:
undetectable
1ykiB-5inwA:
undetectable		 1ykiA-5inwA:
21.88
1ykiB-5inwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		4 / 8 TYR A 161
PHE A 247
GLY A 171
THR A 411
 None
 0.86A 1ykiC-5inwA:
undetectable
1ykiD-5inwA:
undetectable		 1ykiC-5inwA:
21.88
1ykiD-5inwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		4 / 8 THR A 411
TYR A 161
PHE A 247
GLY A 171
 None
 0.91A 1ykiC-5inwA:
undetectable
1ykiD-5inwA:
undetectable		 1ykiC-5inwA:
21.88
1ykiD-5inwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 ALA A 115
GLY A 117
THR A 411
MET A 368
GLY A 367
 None
 0.88A 2hw2A-5inwA:
undetectable		 2hw2A-5inwA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		4 / 7 TYR A 301
THR A 405
VAL A 309
VAL A 297
 None
 0.97A 2qbnA-5inwA:
undetectable		 2qbnA-5inwA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 5inw PUTATIVE
ANGIOTENSINOGEN
C-TERMINAL PEPTIDE
OF PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis;
Lampetra
fluviatilis) 		4 / 7 TYR A 301
THR A 405
VAL C 432
VAL C 442
 None
 0.71A 2qbnA-5inwA:
undetectable		 2qbnA-5inwA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 5inw PUTATIVE
ANGIOTENSINOGEN
C-TERMINAL PEPTIDE
OF PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis;
Lampetra
fluviatilis) 		5 / 10 TYR A 301
THR A 405
VAL C 432
ILE C 443
VAL C 442
 None
 1.36A 2qboA-5inwA:
undetectable		 2qboA-5inwA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		3 / 3 VAL A 229
ASP A 228
GLU A 410
 None
 0.65A 2qeuA-5inwA:
undetectable		 2qeuA-5inwA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		3 / 3 VAL A 229
ASP A 228
GLU A 410
 None
 0.67A 2qeuC-5inwA:
undetectable		 2qeuC-5inwA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 LEU A 359
LEU A  91
VAL A  95
ALA A 115
SER A 356
 None
 1.21A 2vmyB-5inwA:
undetectable		 2vmyB-5inwA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		4 / 5 VAL A 297
TYR A 286
VAL A 344
SER A 347
 None
 1.13A 2x45A-5inwA:
undetectable		 2x45A-5inwA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		3 / 3 ILE A 241
SER A 177
SER A 238
 None
 0.64A 3iltH-5inwA:
undetectable		 3iltH-5inwA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 5inw C-TERMINAL PEPTIDE
OF PUTATIVE
ANGIOTENSINOGEN
PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		4 / 8 SER A 396
PHE A 107
TYR A 357
LEU C 433
 None
 1.10A 3jq7B-5inwA:
undetectable		 3jq7B-5inwA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 5inw C-TERMINAL PEPTIDE
OF PUTATIVE
ANGIOTENSINOGEN
PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		4 / 8 ALA A  83
ALA A  81
THR C 439
LEU A 160
 None
 1.00A 3khmA-5inwA:
undetectable		 3khmA-5inwA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5inw C-TERMINAL PEPTIDE
OF PUTATIVE
ANGIOTENSINOGEN
PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		4 / 5 LEU A 169
TYR A 301
ILE C 434
ALA A 407
 None
 0.98A 3n8yB-5inwA:
undetectable		 3n8yB-5inwA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
C-TERMINAL PEPTIDE
OF PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis;
Lampetra
fluviatilis) 		4 / 5 ASN A 268
ASP C 427
THR A 295
SER A 269
 None
 1.14A 3p2kC-5inwA:
undetectable		 3p2kC-5inwA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 GLY A 338
HIS A 342
LEU A 336
SER A 335
ASP A 289
 None
 1.22A 3pfgA-5inwA:
undetectable		 3pfgA-5inwA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		3 / 3 TYR A 374
ASP A 390
ASP A 236
 None
 0.76A 4a6eA-5inwA:
undetectable		 4a6eA-5inwA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		3 / 3 LYS A  76
TYR A 152
ARG A 155
 None
 1.01A 4gc9A-5inwA:
undetectable		 4gc9A-5inwA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
C-TERMINAL PEPTIDE
OF PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis;
Lampetra
fluviatilis) 		5 / 10 PHE A 247
TYR A 301
THR A 405
ILE C 443
VAL C 442
 None
 1.11A 4jx1B-5inwA:
undetectable		 4jx1B-5inwA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
C-TERMINAL PEPTIDE
OF PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis;
Lampetra
fluviatilis) 		4 / 8 PHE A 351
THR A 405
VAL C 432
VAL C 426
 None
 0.73A 4l4bA-5inwA:
undetectable		 4l4bA-5inwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		4 / 5 GLY A 249
SER A 250
PHE A 167
GLU A 302
 None
 1.01A 4m93B-5inwA:
undetectable
4m93C-5inwA:
undetectable		 4m93B-5inwA:
21.04
4m93C-5inwA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 LEU A 194
GLY A 158
SER A 108
ASN A 173
VAL A 118
 None
 1.44A 5d0yA-5inwA:
undetectable		 5d0yA-5inwA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		6 / 12 LEU A 239
VAL A 119
ALA A 113
VAL A 413
GLY A 414
ILE A 415
 None
 1.23A 5j2tC-5inwA:
undetectable		 5j2tC-5inwA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 5inw PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis) 		5 / 12 ILE A 310
LEU A 330
VAL A 325
GLN A 329
GLU A 332
 None
 1.30A 5l8oB-5inwA:
undetectable		 5l8oB-5inwA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 5inw PUTATIVE
ANGIOTENSINOGEN
C-TERMINAL PEPTIDE
OF PUTATIVE
ANGIOTENSINOGEN
(Lampetra
fluviatilis;
Lampetra
fluviatilis) 		5 / 11 ILE C 434
LEU A 160
GLY A 171
PHE C 444
ALA A 409
 None
 1.33A 6ieyA-5inwC:
undetectable
6ieyB-5inwC:
undetectable		 6ieyA-5inwC:
9.96
6ieyB-5inwC:
9.96