SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ioo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 5ioo AVPA
(Nanoarchaeota
archaeon
JGI
OTU-1) 		5 / 12 ILE A  40
ILE A 131
ILE A 167
ILE A 146
ILE A 169
 None
 1.17A 1r5lA-5iooA:
undetectable		 1r5lA-5iooA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5ioo AVPA
(Nanoarchaeota
archaeon
JGI
OTU-1) 		4 / 7 LEU A  53
VAL A 186
GLY A 187
VAL A 162
 None
 0.85A 1t88A-5iooA:
undetectable		 1t88A-5iooA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5ioo AVPA
(Nanoarchaeota
archaeon
JGI
OTU-1) 		4 / 8 LEU A  53
VAL A 186
GLY A 187
VAL A 162
 None
 0.85A 2a1oA-5iooA:
undetectable		 2a1oA-5iooA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 5ioo AVPA
(Nanoarchaeota
archaeon
JGI
OTU-1) 		4 / 6 ILE A  58
ARG A 182
LEU A 184
ASP A 174
 None
 1.08A 2rlfA-5iooA:
undetectable
2rlfD-5iooA:
undetectable		 2rlfA-5iooA:
10.96
2rlfD-5iooA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 5ioo AVPA
(Nanoarchaeota
archaeon
JGI
OTU-1) 		4 / 6 ASP A 173
ALA A  95
LEU A 180
THR A  61
 None
 1.12A 3rozA-5iooA:
undetectable		 3rozA-5iooA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ioo AVPA
(Nanoarchaeota
archaeon
JGI
OTU-1) 		4 / 5 LEU A 175
GLY A  62
ASP A 119
ILE A 118
 None
 0.97A 5ik1A-5iooA:
undetectable		 5ik1A-5iooA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 5ioo AVPA
(Nanoarchaeota
archaeon
JGI
OTU-1) 		5 / 9 ILE A 131
LEU A 194
GLY A 193
ASN A 192
ALA A 152
 None
 1.34A 5x66C-5iooA:
undetectable		 5x66C-5iooA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ioo AVPA
(Nanoarchaeota
archaeon
JGI
OTU-1) 		3 / 3 LEU A  49
ASN A   4
LEU A  35
 None
 0.73A 6exiD-5iooA:
undetectable		 6exiD-5iooA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5ioo AVPA
(Nanoarchaeota
archaeon
JGI
OTU-1) 		4 / 5 GLY A 129
HIS A 171
SER A 125
SER A 126
 None
 1.00A 6jmjA-5iooA:
undetectable		 6jmjA-5iooA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5ioo AVPA
(Nanoarchaeota
archaeon
JGI
OTU-1) 		4 / 6 GLY A 129
HIS A 171
SER A 125
SER A 126
 None
 1.04A 6jogA-5iooA:
undetectable		 6jogA-5iooA:
22.87