SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ip4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 5ip4 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		3 / 3 ASP D 327
ASP D 322
LYS D 261
 None
 1.07A 1lqtB-5ip4D:
undetectable		 1lqtB-5ip4D:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 5ip4 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		3 / 3 ASP D 327
ASP D 322
LYS D 261
 None
 1.05A 1lquB-5ip4D:
undetectable		 1lquB-5ip4D:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5ip4 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		4 / 7 ILE D 331
LEU D 309
VAL D 306
GLY D 334
 None
 0.78A 2wd9A-5ip4D:
undetectable		 2wd9A-5ip4D:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 5ip4 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		3 / 3 ARG D 267
ARG D 273
PRO D 272
 None
 1.06A 2wljA-5ip4D:
undetectable		 2wljA-5ip4D:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ip4 NEURONAL MIGRATION
PROTEIN DOUBLECORTIN
(Homo
sapiens) 		4 / 6 ASP D 313
THR D 311
TYR D 310
HIS D 321
 None
 1.35A 6nmpA-5ip4D:
undetectable
6nmpC-5ip4D:
undetectable		 6nmpA-5ip4D:
11.35
6nmpC-5ip4D:
16.14