SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ipn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 5ipn RNA POLYMERASE SIGMA
FACTOR RPOS
(Escherichia
coli) 		4 / 5 LEU F 313
LEU F 274
LEU F 280
LEU F 266
 None
 0.94A 1yajD-5ipnF:
2.2		 1yajD-5ipnF:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ipn RNA POLYMERASE SIGMA
FACTOR RPOS
(Escherichia
coli) 		5 / 12 GLN F 161
THR F 153
VAL F 172
LEU F 167
ILE F 169
 None
 1.20A 3elzC-5ipnF:
undetectable		 3elzC-5ipnF:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 5ipn RNA POLYMERASE SIGMA
FACTOR RPOS
(Escherichia
coli) 		3 / 3 ALA F 285
PHE F 278
GLN F 306
 None
 0.84A 6eceA-5ipnF:
undetectable		 6eceA-5ipnF:
22.97