SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ipw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		3 / 3 GLU A 620
ALA A 359
SER A 623
 None
 0.68A 1errB-5ipwA:
undetectable		 1errB-5ipwA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 7 HIS A 219
LEU A 262
ASP A 149
PHE A 224
 None
 1.22A 1ismB-5ipwA:
undetectable		 1ismB-5ipwA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		3 / 3 ALA A 155
HIS A 156
VAL A 159
 None
 0.42A 1lqtB-5ipwA:
undetectable		 1lqtB-5ipwA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		3 / 3 ALA A 155
HIS A 156
VAL A 159
 None
 0.41A 1lquB-5ipwA:
undetectable		 1lquB-5ipwA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 7 ASP A 301
PHE A  85
PRO A  51
THR A  54
 None
 1.39A 2q6kA-5ipwA:
undetectable		 2q6kA-5ipwA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 6 ASP A 301
PHE A  85
PRO A  51
THR A  54
 None
 1.44A 2q6oB-5ipwA:
undetectable		 2q6oB-5ipwA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 6 PHE A 195
PHE A 204
GLY A 212
GLY A 211
 None
 1.00A 2qr2A-5ipwA:
undetectable
2qr2B-5ipwA:
undetectable		 2qr2A-5ipwA:
16.75
2qr2B-5ipwA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 5 GLY A 212
GLY A 211
PHE A 195
PHE A 204
 None
 1.01A 2qr2A-5ipwA:
undetectable
2qr2B-5ipwA:
undetectable		 2qr2A-5ipwA:
16.75
2qr2B-5ipwA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 7 PRO A 200
ILE A 181
PRO A 592
GLY A 202
 None
 0.91A 2y7kA-5ipwA:
2.3		 2y7kA-5ipwA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		5 / 8 ARG A 645
ALA A 359
ASP A 621
GLY A 331
PRO A 647
 None
 1.48A 3el9A-5ipwA:
undetectable		 3el9A-5ipwA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		5 / 11 GLN A 326
PRO A 652
TYR A 210
ILE A 106
PRO A 267
 None
 1.17A 3ganA-5ipwA:
undetectable		 3ganA-5ipwA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 6 PHE A 139
TYR A 137
VAL A 162
PHE A 204
 None
 1.31A 3ltwA-5ipwA:
undetectable		 3ltwA-5ipwA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		5 / 12 GLY A 362
ALA A 414
LEU A 416
VAL A 417
ILE A 358
 None
 1.14A 4aztA-5ipwA:
undetectable		 4aztA-5ipwA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		5 / 9 GLY A  27
VAL A  76
PRO A  78
GLU A 658
GLY A  83
 None
 1.09A 4fimA-5ipwA:
3.3		 4fimA-5ipwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		5 / 12 LEU A 203
PRO A 526
GLN A 525
ASP A 593
ASP A 595
 None
 1.40A 4j7xJ-5ipwA:
undetectable		 4j7xJ-5ipwA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		5 / 12 PHE A 287
GLY A 294
ILE A 292
ARG A 142
LEU A  74
 None
 1.40A 4kotA-5ipwA:
1.1		 4kotA-5ipwA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		3 / 3 ARG A 353
LEU A 355
GLU A 636
 None
 0.65A 4l3gF-5ipwA:
undetectable		 4l3gF-5ipwA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 5 VAL A 193
LEU A 110
VAL A 208
PHE A 195
 None
 0.99A 4lb0B-5ipwA:
undetectable		 4lb0B-5ipwA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		3 / 3 ASP A 189
LYS A 194
LEU A 131
 None
 0.95A 4ptjA-5ipwA:
undetectable		 4ptjA-5ipwA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		5 / 11 ASP A 557
VAL A 582
ASP A 583
TYR A 586
GLY A 550
 None
 1.17A 4xnxA-5ipwA:
undetectable		 4xnxA-5ipwA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 6 ILE A 400
LEU A 404
PHE A 405
ARG A 366
 None
 1.07A 5b1aN-5ipwA:
undetectable
5b1aW-5ipwA:
undetectable		 5b1aN-5ipwA:
20.41
5b1aW-5ipwA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		5 / 12 ILE A 490
VAL A 381
ALA A 390
ILE A 395
ALA A 394
 None
 1.05A 5n0tB-5ipwA:
undetectable		 5n0tB-5ipwA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		5 / 12 VAL A 381
PHE A 382
PHE A 387
GLN A 489
ILE A 496
 None
 1.46A 6becA-5ipwA:
undetectable
6becB-5ipwA:
undetectable
6becC-5ipwA:
undetectable		 6becA-5ipwA:
20.31
6becB-5ipwA:
20.31
6becC-5ipwA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 8 ASP A 301
ILE A 300
TRP A  89
ARG A 283
 None
 1.22A 6hisA-5ipwA:
undetectable
6hisB-5ipwA:
undetectable		 6hisA-5ipwA:
9.22
6hisB-5ipwA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 8 ASP A 301
ILE A 300
TRP A  89
ARG A 283
 None
 1.22A 6hisB-5ipwA:
undetectable
6hisC-5ipwA:
undetectable		 6hisB-5ipwA:
9.22
6hisC-5ipwA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 8 ASP A 301
ILE A 300
TRP A  89
ARG A 283
 None
 1.21A 6hisC-5ipwA:
undetectable
6hisD-5ipwA:
undetectable		 6hisC-5ipwA:
9.22
6hisD-5ipwA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 8 ASP A 301
ILE A 300
TRP A  89
ARG A 283
 None
 1.23A 6hisD-5ipwA:
undetectable
6hisE-5ipwA:
undetectable		 6hisD-5ipwA:
9.22
6hisE-5ipwA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 8 ASP A 301
ILE A 300
TRP A  89
ARG A 283
 None
 1.22A 6hisA-5ipwA:
undetectable
6hisE-5ipwA:
undetectable		 6hisA-5ipwA:
9.22
6hisE-5ipwA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		3 / 3 ARG A 283
PHE A 655
PHE A 287
 None
 1.00A 6nknC-5ipwA:
undetectable
6nknJ-5ipwA:
undetectable		 6nknC-5ipwA:
17.47
6nknJ-5ipwA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE
(Thermotoga
maritima) 		4 / 7 ALA A 337
GLY A 338
LEU A 342
GLY A 331
 None
 0.84A 6nm4A-5ipwA:
undetectable		 6nm4A-5ipwA:
16.38