SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ipx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 8 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.86A 1v54C-5ipxA:
undetectable
1v54J-5ipxA:
undetectable		 1v54C-5ipxA:
20.47
1v54J-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 8 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.80A 1v54P-5ipxA:
0.0
1v54W-5ipxA:
undetectable		 1v54P-5ipxA:
20.47
1v54W-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 8 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.88A 2dyrC-5ipxA:
0.0
2dyrJ-5ipxA:
undetectable		 2dyrC-5ipxA:
20.47
2dyrJ-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 8 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.82A 2dyrP-5ipxA:
0.0
2dyrW-5ipxA:
undetectable		 2dyrP-5ipxA:
20.47
2dyrW-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.87A 2eikC-5ipxA:
undetectable
2eikJ-5ipxA:
undetectable		 2eikC-5ipxA:
20.47
2eikJ-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 8 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.87A 2eikP-5ipxA:
undetectable
2eikW-5ipxA:
undetectable		 2eikP-5ipxA:
20.47
2eikW-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 8 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.87A 2eilC-5ipxA:
0.0
2eilJ-5ipxA:
undetectable		 2eilC-5ipxA:
20.47
2eilJ-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.87A 2eimP-5ipxA:
0.0
2eimW-5ipxA:
undetectable		 2eimP-5ipxA:
20.47
2eimW-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 6 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.90A 3abkP-5ipxA:
undetectable
3abkW-5ipxA:
undetectable		 3abkP-5ipxA:
20.47
3abkW-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.93A 3ag2P-5ipxA:
7.2
3ag2W-5ipxA:
undetectable		 3ag2P-5ipxA:
20.47
3ag2W-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 8 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.86A 3ag4C-5ipxA:
0.0
3ag4J-5ipxA:
undetectable		 3ag4C-5ipxA:
20.47
3ag4J-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.84A 3ag4P-5ipxA:
0.0
3ag4W-5ipxA:
undetectable		 3ag4P-5ipxA:
20.47
3ag4W-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.85A 3asnC-5ipxA:
0.0
3asnJ-5ipxA:
undetectable		 3asnC-5ipxA:
20.47
3asnJ-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.81A 3asnP-5ipxA:
undetectable
3asnW-5ipxA:
undetectable		 3asnP-5ipxA:
20.47
3asnW-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.80A 3asoP-5ipxA:
undetectable
3asoW-5ipxA:
undetectable		 3asoP-5ipxA:
20.47
3asoW-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		3 / 3 HIS A 290
PHE A 248
PHE A 249
 None
 0.57A 3lk0D-5ipxA:
undetectable		 3lk0D-5ipxA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 HIS A 151
ARG A 160
GLY A 154
ALA A 155
LEU A 159
 None
SO4  A 402 (-4.1A)
None
None
None
 1.11A 3n8xA-5ipxA:
undetectable		 3n8xA-5ipxA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 ARG A 160
VAL A 153
GLY A 154
ALA A 155
LEU A 159
 SO4  A 402 (-4.1A)
None
None
None
None
 0.99A 3nt1A-5ipxA:
undetectable		 3nt1A-5ipxA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 ARG A 160
VAL A 153
GLY A 154
ALA A 155
LEU A 159
 SO4  A 402 (-4.1A)
None
None
None
None
 0.99A 3nt1B-5ipxA:
undetectable		 3nt1B-5ipxA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 ARG A 160
VAL A 153
GLY A 154
ALA A 155
LEU A 159
 SO4  A 402 (-4.1A)
None
None
None
None
 0.95A 3rr3A-5ipxA:
undetectable		 3rr3A-5ipxA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 VAL A 163
VAL A 153
GLY A 154
ALA A 155
LEU A 159
 None
 1.08A 3rr3A-5ipxA:
undetectable		 3rr3A-5ipxA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 ARG A 160
VAL A 153
GLY A 154
ALA A 155
LEU A 159
 SO4  A 402 (-4.1A)
None
None
None
None
 0.95A 3rr3B-5ipxA:
undetectable		 3rr3B-5ipxA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 VAL A 163
VAL A 153
GLY A 154
ALA A 155
LEU A 159
 None
 1.07A 3rr3B-5ipxA:
undetectable		 3rr3B-5ipxA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 6 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.82A 3wg7C-5ipxA:
8.1
3wg7J-5ipxA:
undetectable		 3wg7C-5ipxA:
20.47
3wg7J-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.84A 3x2qC-5ipxA:
0.0
3x2qJ-5ipxA:
undetectable		 3x2qC-5ipxA:
20.47
3x2qJ-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.91A 3x2qP-5ipxA:
undetectable
3x2qW-5ipxA:
undetectable		 3x2qP-5ipxA:
20.47
3x2qW-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 4 HIS A 232
GLU A  69
HIS A  19
LEU A  15
 None
 1.21A 4m2rA-5ipxA:
undetectable		 4m2rA-5ipxA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 GLU A 114
LEU A 117
LEU A  80
LEU A  84
 None
 0.80A 4wg0B-5ipxA:
undetectable
4wg0C-5ipxA:
undetectable		 4wg0B-5ipxA:
6.92
4wg0C-5ipxA:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 LEU A  87
GLY A 101
ASN A 100
LEU A 121
CYH A 211
 None
 1.20A 4x61A-5ipxA:
undetectable		 4x61A-5ipxA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.78A 5b1bP-5ipxA:
undetectable
5b1bW-5ipxA:
undetectable		 5b1bP-5ipxA:
20.47
5b1bW-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 LEU A  87
GLY A 101
ASN A 100
LEU A 121
CYH A 211
 None
 1.30A 5emlA-5ipxA:
undetectable		 5emlA-5ipxA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 4 CYH A 211
PHE A 212
ILE A  95
GLY A 120
 None
 1.15A 5hesB-5ipxA:
undetectable		 5hesB-5ipxA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		6 / 12 ARG A 160
LEU A 208
VAL A 153
GLY A 154
ALA A 155
LEU A 159
 SO4  A 402 (-4.1A)
None
None
None
None
None
 1.48A 5ikqB-5ipxA:
undetectable		 5ikqB-5ipxA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 ARG A 160
VAL A 153
GLY A 154
ALA A 155
LEU A 159
 SO4  A 402 (-4.1A)
None
None
None
None
 1.06A 5ikrA-5ipxA:
0.8		 5ikrA-5ipxA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 VAL A 163
VAL A 153
GLY A 154
ALA A 155
LEU A 159
 None
 1.10A 5iktA-5ipxA:
undetectable		 5iktA-5ipxA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		5 / 12 ARG A 160
VAL A 153
GLY A 154
ALA A 155
LEU A 159
 SO4  A 402 (-4.1A)
None
None
None
None
 1.00A 5jvzA-5ipxA:
undetectable		 5jvzA-5ipxA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		3 / 3 LYS A 295
HIS A 292
HIS A 296
 None
None
SO4  A 403 (-3.4A)
 1.03A 5oexA-5ipxA:
undetectable		 5oexA-5ipxA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		3 / 3 LYS A 295
HIS A 292
HIS A 296
 None
None
SO4  A 403 (-3.4A)
 1.00A 5oexB-5ipxA:
undetectable		 5oexB-5ipxA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		3 / 3 LYS A 295
HIS A 292
HIS A 296
 None
None
SO4  A 403 (-3.4A)
 1.00A 5oexC-5ipxA:
undetectable		 5oexC-5ipxA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		3 / 3 LYS A 295
HIS A 292
HIS A 296
 None
None
SO4  A 403 (-3.4A)
 0.98A 5oexD-5ipxA:
undetectable		 5oexD-5ipxA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 5 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.77A 5x19C-5ipxA:
3.7
5x19J-5ipxA:
undetectable		 5x19C-5ipxA:
20.47
5x19J-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.81A 5x1fP-5ipxA:
8.2
5x1fW-5ipxA:
undetectable		 5x1fP-5ipxA:
20.47
5x1fW-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.76A 5z85C-5ipxA:
0.0
5z85J-5ipxA:
undetectable		 5z85C-5ipxA:
20.47
5z85J-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.75A 5zcoC-5ipxA:
0.0
5zcoJ-5ipxA:
undetectable		 5zcoC-5ipxA:
20.47
5zcoJ-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.76A 5zcqC-5ipxA:
undetectable
5zcqJ-5ipxA:
undetectable		 5zcqC-5ipxA:
20.47
5zcqJ-5ipxA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ipx ORF49 PROTEIN
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  87
PHE A 204
LEU A 208
PHE A 212
 None
 0.78A 5zcqP-5ipxA:
undetectable
5zcqW-5ipxA:
undetectable		 5zcqP-5ipxA:
20.47
5zcqW-5ipxA:
11.04