SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5iq9 10E8V4 HEAVY CHAIN
(Homo
sapiens) 		5 / 10 THR A  95
PHE A 100
ALA A  93
VAL A  63
ILE A  69
 None
 1.13A 1claA-5iq9A:
undetectable		 1claA-5iq9A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5iq9 10E8V4 HEAVY CHAIN
(Homo
sapiens) 		4 / 6 SER A  56
PRO A  52
GLY A  52
TRP A  33
 None
 1.45A 2y7pA-5iq9A:
undetectable		 2y7pA-5iq9A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5iq9 10E8V4 HEAVY CHAIN
GP41 MPER PEPTIDE
(Homo
sapiens;
Human
immunodeficiency
virus
1) 		4 / 8 TRP C 672
THR A  95
TYR A  98
TYR A 100
 None
 1.43A 3wipA-5iq9C:
undetectable
3wipE-5iq9C:
undetectable		 3wipA-5iq9C:
14.39
3wipE-5iq9C:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 5iq9 10E8V4 HEAVY CHAIN
GP41 MPER PEPTIDE
(Homo
sapiens;
Human
immunodeficiency
virus
1) 		4 / 7 GLY A  96
THR A  95
THR C 676
PHE C 673
 None
 0.88A 4ac9C-5iq9A:
undetectable		 4ac9C-5iq9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5iq9 10E8V4 HEAVY CHAIN
GP41 MPER PEPTIDE
(Homo
sapiens;
Human
immunodeficiency
virus
1) 		4 / 7 GLY A  96
THR A  95
THR C 676
PHE C 673
 None
 0.88A 4acaC-5iq9A:
undetectable		 4acaC-5iq9A:
19.41