SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 5iql YEATS
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 6 VAL A 212
VAL A 327
ILE A 247
ARG A 288
 None
 1.08A 3pyyA-5iqlA:
undetectable		 3pyyA-5iqlA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 5iql YEATS
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 7 ASP A 228
GLY A 283
SER A 230
GLY A 281
 None
 0.88A 6ekzA-5iqlA:
undetectable		 6ekzA-5iqlA:
20.47