SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5iqn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 5iqn PROTEIN FIMG
(Escherichia
coli) 		5 / 11 LEU A  27
GLY A  79
ALA A 135
LEU A  86
SER A  42
 None
 1.17A 2bxgA-5iqnA:
undetectable		 2bxgA-5iqnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5iqn PROTEIN FIMG
(Escherichia
coli) 		3 / 3 THR A  95
ASN A  97
GLU A  87
 None
 0.58A 3v4tA-5iqnA:
undetectable
3v4tC-5iqnA:
undetectable		 3v4tA-5iqnA:
15.04
3v4tC-5iqnA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 5iqn PROTEIN FIMG
(Escherichia
coli) 		5 / 10 PHE A  65
VAL A  61
TYR A 143
PHE A 115
SER A  64
 None
 1.44A 4xpbA-5iqnA:
undetectable		 4xpbA-5iqnA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 5iqn PROTEIN FIMG
(Escherichia
coli) 		4 / 6 GLY A  99
THR A  98
SER A  66
GLY A  67
 None
 0.89A 5k4pA-5iqnA:
undetectable		 5k4pA-5iqnA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 5iqn PROTEIN FIMG
(Escherichia
coli) 		5 / 9 ALA A  41
SER A  42
GLY A  39
ALA A 128
GLY A 126
 None
 1.20A 6bklE-5iqnA:
undetectable
6bklF-5iqnA:
undetectable
6bklG-5iqnA:
undetectable
6bklH-5iqnA:
undetectable		 6bklE-5iqnA:
9.85
6bklF-5iqnA:
9.85
6bklG-5iqnA:
9.85
6bklH-5iqnA:
9.85