SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5irm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 ILE A 497
TYR A 494
PHE A 589
PHE A 657
None
1.20A 1e71M-5irmA:
undetectable
1e71M-5irmA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 ILE A 497
TYR A 494
PHE A 589
PHE A 657
None
1.21A 1e72M-5irmA:
undetectable
1e72M-5irmA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 830
LEU A 828
PHE A 853
VAL A 843
ALA A 819
None
1.03A 1n5xA-5irmA:
undetectable
1n5xA-5irmA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 830
LEU A 828
PHE A 853
VAL A 843
ALA A 819
None
1.03A 1n5xB-5irmA:
undetectable
1n5xB-5irmA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 959
VAL A 952
ILE A 975
LEU A1018
LEU A1011
None
0.98A 1s19A-5irmA:
undetectable
1s19A-5irmA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 CYH A 953
LEU A 955
ALA A 956
VAL A 996
LEU A1011
None
1.15A 1s9pB-5irmA:
undetectable
1s9pB-5irmA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 5 PHE A 719
LEU A 762
VAL A 765
VAL A 744
None
1.17A 1t88B-5irmA:
undetectable
1t88B-5irmA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.47A 1v54A-5irmA:
undetectable
1v54C-5irmA:
undetectable
1v54A-5irmA:
20.45
1v54C-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.43A 1v54N-5irmA:
undetectable
1v54P-5irmA:
undetectable
1v54N-5irmA:
20.45
1v54P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.46A 1v55A-5irmA:
undetectable
1v55C-5irmA:
undetectable
1v55A-5irmA:
20.45
1v55C-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.91A 1v55C-5irmA:
undetectable
1v55N-5irmA:
undetectable
1v55P-5irmA:
undetectable
1v55C-5irmA:
15.38
1v55N-5irmA:
20.45
1v55P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 ALA A 900
GLN A 897
LEU A 927
ALA A 926
LEU A 871
None
1.14A 1xdkA-5irmA:
undetectable
1xdkA-5irmA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 ALA A 900
GLN A 897
LEU A 927
ALA A 926
LEU A 871
None
1.00A 1xiuA-5irmA:
undetectable
1xiuA-5irmA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 527
LEU A 530
LEU A 533
ALA A 534
LEU A 582
None
1.11A 1ya3C-5irmA:
undetectable
1ya3C-5irmA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
3 / 3 TRP A 470
THR A 585
TYR A 494
ADP  A1101 ( 4.8A)
None
None
1.28A 2a3aA-5irmA:
undetectable
2a3aA-5irmA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 968
LEU A 983
GLY A 958
ALA A 928
ALA A 926
None
1.13A 2bm9C-5irmA:
undetectable
2bm9C-5irmA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 968
LEU A 983
GLY A 958
ALA A 928
ALA A 926
None
1.05A 2br4A-5irmA:
undetectable
2br4A-5irmA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 968
LEU A 983
GLY A 958
ALA A 928
ALA A 926
None
1.10A 2br4C-5irmA:
undetectable
2br4C-5irmA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 968
LEU A 983
GLY A 958
ALA A 928
ALA A 926
None
1.05A 2br4D-5irmA:
undetectable
2br4D-5irmA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 968
LEU A 983
GLY A 958
ALA A 928
ALA A 926
None
1.06A 2br4E-5irmA:
undetectable
2br4E-5irmA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.47A 2dyrA-5irmA:
undetectable
2dyrC-5irmA:
undetectable
2dyrA-5irmA:
20.45
2dyrC-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.45A 2dyrN-5irmA:
undetectable
2dyrP-5irmA:
undetectable
2dyrN-5irmA:
20.45
2dyrP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.46A 2eijA-5irmA:
undetectable
2eijC-5irmA:
undetectable
2eijA-5irmA:
20.45
2eijC-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.44A 2eijN-5irmA:
undetectable
2eijP-5irmA:
undetectable
2eijN-5irmA:
20.45
2eijP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.46A 2eikA-5irmA:
undetectable
2eikC-5irmA:
undetectable
2eikA-5irmA:
20.45
2eikC-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.45A 2eikN-5irmA:
undetectable
2eikP-5irmA:
undetectable
2eikN-5irmA:
20.45
2eikP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.44A 2eilA-5irmA:
undetectable
2eilC-5irmA:
undetectable
2eilA-5irmA:
20.45
2eilC-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.44A 2eilN-5irmA:
undetectable
2eilP-5irmA:
undetectable
2eilN-5irmA:
20.45
2eilP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 GLY A 811
GLY A 786
ASP A 809
LEU A 856
VAL A 782
None
1.06A 2hmyB-5irmA:
undetectable
2hmyB-5irmA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 SER A 880
LEU A 899
GLY A 874
VAL A 843
ALA A 840
None
1.31A 2kceA-5irmA:
undetectable
2kceA-5irmA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 884
PHE A 853
SER A 880
GLY A 859
LEU A 835
None
1.16A 2lbdA-5irmA:
undetectable
2lbdA-5irmA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 PHE A 309
LEU A 323
VAL A 319
LEU A 347
LEU A 396
None
1.33A 2prgB-5irmA:
undetectable
2prgB-5irmA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 11 ALA A 399
LEU A 386
LEU A 328
LEU A 356
LEU A 316
None
1.00A 2xn5A-5irmA:
undetectable
2xn5A-5irmA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 11 ALA A 819
LEU A 858
LEU A 856
LEU A 846
LEU A 871
None
1.02A 2xn5A-5irmA:
undetectable
2xn5A-5irmA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.45A 2y69A-5irmA:
undetectable
2y69C-5irmA:
undetectable
2y69A-5irmA:
20.45
2y69C-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.95A 2y69C-5irmA:
undetectable
2y69N-5irmA:
undetectable
2y69P-5irmA:
undetectable
2y69C-5irmA:
15.38
2y69N-5irmA:
20.45
2y69P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.45A 3abkA-5irmA:
undetectable
3abkC-5irmA:
undetectable
3abkA-5irmA:
20.45
3abkC-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.47A 3abkN-5irmA:
undetectable
3abkP-5irmA:
undetectable
3abkN-5irmA:
20.45
3abkP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.97A 3ablA-5irmA:
undetectable
3ablC-5irmA:
undetectable
3ablP-5irmA:
undetectable
3ablA-5irmA:
20.45
3ablC-5irmA:
15.38
3ablP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.95A 3ablC-5irmA:
undetectable
3ablN-5irmA:
undetectable
3ablP-5irmA:
undetectable
3ablC-5irmA:
15.38
3ablN-5irmA:
20.45
3ablP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.89A 3abmA-5irmA:
undetectable
3abmC-5irmA:
undetectable
3abmP-5irmA:
undetectable
3abmA-5irmA:
20.45
3abmC-5irmA:
15.38
3abmP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.48A 3abmN-5irmA:
undetectable
3abmP-5irmA:
undetectable
3abmN-5irmA:
20.45
3abmP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.46A 3ag2A-5irmA:
undetectable
3ag2C-5irmA:
undetectable
3ag2A-5irmA:
20.45
3ag2C-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.44A 3ag2N-5irmA:
undetectable
3ag2P-5irmA:
undetectable
3ag2N-5irmA:
20.45
3ag2P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.45A 3ag3A-5irmA:
undetectable
3ag3C-5irmA:
undetectable
3ag3A-5irmA:
20.45
3ag3C-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.47A 3ag3N-5irmA:
undetectable
3ag3P-5irmA:
undetectable
3ag3N-5irmA:
20.45
3ag3P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.47A 3ag4A-5irmA:
undetectable
3ag4C-5irmA:
undetectable
3ag4A-5irmA:
20.45
3ag4C-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.46A 3ag4N-5irmA:
undetectable
3ag4P-5irmA:
undetectable
3ag4N-5irmA:
20.45
3ag4P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.96A 3asnC-5irmA:
undetectable
3asnN-5irmA:
undetectable
3asnP-5irmA:
undetectable
3asnC-5irmA:
15.38
3asnN-5irmA:
20.45
3asnP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.95A 3asoA-5irmA:
undetectable
3asoC-5irmA:
undetectable
3asoP-5irmA:
undetectable
3asoA-5irmA:
20.45
3asoC-5irmA:
15.38
3asoP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.98A 3asoC-5irmA:
undetectable
3asoN-5irmA:
undetectable
3asoP-5irmA:
undetectable
3asoC-5irmA:
15.38
3asoN-5irmA:
20.45
3asoP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 5 LEU A 436
GLN A 454
HIS A 476
LEU A 480
None
1.16A 3ce6D-5irmA:
undetectable
3ce6D-5irmA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_E_C2FE995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 11 THR A 491
GLN A 674
LEU A 597
LEU A 662
ARG A 684
None
1.48A 3fsuE-5irmA:
undetectable
3fsuE-5irmA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 6 PHE A 719
LEU A 762
VAL A 765
VAL A 744
None
1.10A 3fwgA-5irmA:
undetectable
3fwgA-5irmA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 912
ASN A 945
LEU A 955
LEU A 927
GLY A 923
None
1.34A 3g1uA-5irmA:
undetectable
3g1uA-5irmA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 GLY A 786
GLY A 783
ALA A 757
ALA A 760
SER A 808
None
0.99A 3mteA-5irmA:
undetectable
3mteA-5irmA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 GLY A 786
GLY A 783
ALA A 757
ALA A 760
SER A 808
None
1.01A 3p2kD-5irmA:
undetectable
3p2kD-5irmA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.91A 3wg7A-5irmA:
undetectable
3wg7C-5irmA:
undetectable
3wg7P-5irmA:
undetectable
3wg7A-5irmA:
20.45
3wg7C-5irmA:
15.38
3wg7P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.95A 3wg7C-5irmA:
undetectable
3wg7N-5irmA:
undetectable
3wg7P-5irmA:
undetectable
3wg7C-5irmA:
15.38
3wg7N-5irmA:
20.45
3wg7P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.89A 3x2qA-5irmA:
undetectable
3x2qC-5irmA:
undetectable
3x2qP-5irmA:
undetectable
3x2qA-5irmA:
20.45
3x2qC-5irmA:
15.38
3x2qP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.94A 3x2qC-5irmA:
undetectable
3x2qN-5irmA:
undetectable
3x2qP-5irmA:
undetectable
3x2qC-5irmA:
15.38
3x2qN-5irmA:
20.45
3x2qP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 5 ARG A 406
ILE A 584
HIS A 583
GLY A 282
None
None
ADP  A1101 (-3.9A)
ADP  A1101 (-3.2A)
1.35A 4e7cC-5irmA:
undetectable
4e7cC-5irmA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 PHE A 719
PHE A 699
LEU A 769
LEU A 742
None
0.92A 4ejgB-5irmA:
undetectable
4ejgB-5irmA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 6 PHE A 719
LEU A 762
VAL A 765
VAL A 744
None
1.11A 4ek1A-5irmA:
undetectable
4ek1A-5irmA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 4 LEU A 347
LEU A 306
GLN A 340
GLU A 195
None
0.88A 4i41A-5irmA:
undetectable
4i41A-5irmA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 6 PHE A 719
LEU A 762
VAL A 765
VAL A 744
None
1.16A 4kkyX-5irmA:
undetectable
4kkyX-5irmA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 5 PHE A 719
LEU A 762
VAL A 765
VAL A 744
None
1.19A 4l49A-5irmA:
undetectable
4l49A-5irmA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 5 ASN A 945
LEU A 947
SER A 971
LEU A 968
None
1.29A 4n09C-5irmA:
undetectable
4n09C-5irmA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 10 LEU A 856
LEU A 800
LEU A 815
ILE A 816
LEU A 847
None
1.08A 4odoC-5irmA:
undetectable
4odoC-5irmA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 9 VAL A 601
LEU A 670
LEU A 606
SER A 679
LEU A 680
None
1.31A 4ubsA-5irmA:
undetectable
4ubsA-5irmA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 11 ALA A 926
LEU A 927
LEU A 914
LEU A 912
LEU A 940
None
1.23A 4wg0I-5irmA:
undetectable
4wg0J-5irmA:
undetectable
4wg0K-5irmA:
undetectable
4wg0I-5irmA:
1.82
4wg0J-5irmA:
1.82
4wg0K-5irmA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ARG A 529
VAL A 555
ASP A 558
ASP A 559
None
0.83A 4xqgA-5irmA:
undetectable
4xqgA-5irmA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ARG A 529
VAL A 555
ASP A 558
ASP A 559
None
0.82A 4xqgB-5irmA:
undetectable
4xqgB-5irmA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.93A 5b1aA-5irmA:
undetectable
5b1aC-5irmA:
undetectable
5b1aP-5irmA:
undetectable
5b1aA-5irmA:
20.45
5b1aC-5irmA:
15.38
5b1aP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.46A 5b1aN-5irmA:
undetectable
5b1aP-5irmA:
undetectable
5b1aN-5irmA:
20.45
5b1aP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
1.02A 5b1bA-5irmA:
undetectable
5b1bC-5irmA:
undetectable
5b1bP-5irmA:
undetectable
5b1bA-5irmA:
20.45
5b1bC-5irmA:
15.38
5b1bP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.45A 5b1bN-5irmA:
undetectable
5b1bP-5irmA:
undetectable
5b1bN-5irmA:
20.45
5b1bP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.92A 5b3sA-5irmA:
undetectable
5b3sC-5irmA:
undetectable
5b3sP-5irmA:
undetectable
5b3sA-5irmA:
20.45
5b3sC-5irmA:
15.38
5b3sP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.46A 5b3sN-5irmA:
undetectable
5b3sP-5irmA:
undetectable
5b3sN-5irmA:
20.45
5b3sP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 6 HIS A 440
LEU A 436
CYH A 475
LEU A 479
None
1.48A 5hrqD-5irmA:
undetectable
5hrqG-5irmA:
undetectable
5hrqH-5irmA:
undetectable
5hrqD-5irmA:
3.36
5hrqG-5irmA:
2.25
5hrqH-5irmA:
3.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.46A 5iy5A-5irmA:
undetectable
5iy5C-5irmA:
undetectable
5iy5A-5irmA:
20.45
5iy5C-5irmA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.94A 5iy5C-5irmA:
undetectable
5iy5N-5irmA:
undetectable
5iy5P-5irmA:
undetectable
5iy5C-5irmA:
15.28
5iy5N-5irmA:
20.45
5iy5P-5irmA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 4 ASN A 945
LEU A 947
SER A 971
LEU A 968
None
1.26A 5kb5A-5irmA:
undetectable
5kb5A-5irmA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 ALA A 950
GLY A 951
ASN A 972
GLU A 944
LEU A 942
None
1.23A 5nwuA-5irmA:
undetectable
5nwuA-5irmA:
3.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 GLY A 885
SER A 913
GLU A 938
LEU A 937
LEU A 940
None
1.22A 5nwvA-5irmA:
undetectable
5nwvA-5irmA:
3.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 609
LEU A 595
LEU A 535
ALA A 640
GLU A 636
None
1.14A 5v0vA-5irmA:
2.6
5v0vA-5irmA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.90A 5w97A-5irmA:
undetectable
5w97C-5irmA:
undetectable
5w97c-5irmA:
undetectable
5w97A-5irmA:
20.45
5w97C-5irmA:
15.38
5w97c-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.96A 5w97C-5irmA:
undetectable
5w97a-5irmA:
undetectable
5w97c-5irmA:
undetectable
5w97C-5irmA:
15.38
5w97a-5irmA:
20.45
5w97c-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.90A 5wauA-5irmA:
undetectable
5wauC-5irmA:
undetectable
5wauc-5irmA:
undetectable
5wauA-5irmA:
20.45
5wauC-5irmA:
15.38
5wauc-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.90A 5wauC-5irmA:
undetectable
5waua-5irmA:
undetectable
5wauc-5irmA:
undetectable
5wauC-5irmA:
15.38
5waua-5irmA:
20.45
5wauc-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.98A 5x19A-5irmA:
undetectable
5x19C-5irmA:
undetectable
5x19P-5irmA:
undetectable
5x19A-5irmA:
20.45
5x19C-5irmA:
15.38
5x19P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
1.03A 5x1bA-5irmA:
undetectable
5x1bC-5irmA:
undetectable
5x1bP-5irmA:
undetectable
5x1bA-5irmA:
20.45
5x1bC-5irmA:
15.38
5x1bP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.95A 5x1fA-5irmA:
undetectable
5x1fC-5irmA:
undetectable
5x1fP-5irmA:
undetectable
5x1fA-5irmA:
20.45
5x1fC-5irmA:
15.38
5x1fP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.48A 5x1fN-5irmA:
undetectable
5x1fP-5irmA:
undetectable
5x1fN-5irmA:
20.45
5x1fP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.93A 5xdqA-5irmA:
undetectable
5xdqC-5irmA:
undetectable
5xdqP-5irmA:
undetectable
5xdqA-5irmA:
20.45
5xdqC-5irmA:
15.38
5xdqP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.93A 5xdqC-5irmA:
undetectable
5xdqN-5irmA:
undetectable
5xdqP-5irmA:
undetectable
5xdqC-5irmA:
15.38
5xdqN-5irmA:
20.45
5xdqP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.95A 5xdxC-5irmA:
undetectable
5xdxN-5irmA:
undetectable
5xdxP-5irmA:
undetectable
5xdxC-5irmA:
15.04
5xdxN-5irmA:
20.45
5xdxP-5irmA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 LEU A 495
LEU A 528
PRO A 525
THR A 526
LEU A 562
None
1.00A 5xxiA-5irmA:
undetectable
5xxiA-5irmA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.92A 5z84A-5irmA:
undetectable
5z84C-5irmA:
undetectable
5z84P-5irmA:
undetectable
5z84A-5irmA:
20.45
5z84C-5irmA:
15.38
5z84P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.96A 5z84C-5irmA:
undetectable
5z84N-5irmA:
undetectable
5z84P-5irmA:
undetectable
5z84C-5irmA:
15.38
5z84N-5irmA:
20.45
5z84P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.91A 5z85A-5irmA:
1.7
5z85C-5irmA:
undetectable
5z85P-5irmA:
undetectable
5z85A-5irmA:
20.45
5z85C-5irmA:
15.38
5z85P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.95A 5z85C-5irmA:
undetectable
5z85N-5irmA:
undetectable
5z85P-5irmA:
undetectable
5z85C-5irmA:
15.38
5z85N-5irmA:
20.45
5z85P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.90A 5z86A-5irmA:
undetectable
5z86C-5irmA:
undetectable
5z86P-5irmA:
undetectable
5z86A-5irmA:
20.45
5z86C-5irmA:
15.38
5z86P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.96A 5z86C-5irmA:
undetectable
5z86N-5irmA:
undetectable
5z86P-5irmA:
undetectable
5z86C-5irmA:
15.38
5z86N-5irmA:
20.45
5z86P-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.91A 5zcoA-5irmA:
undetectable
5zcoC-5irmA:
undetectable
5zcoP-5irmA:
undetectable
5zcoA-5irmA:
20.45
5zcoC-5irmA:
15.38
5zcoP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.93A 5zcoC-5irmA:
undetectable
5zcoN-5irmA:
1.5
5zcoP-5irmA:
undetectable
5zcoC-5irmA:
15.38
5zcoN-5irmA:
20.45
5zcoP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.94A 5zcpA-5irmA:
undetectable
5zcpC-5irmA:
undetectable
5zcpP-5irmA:
undetectable
5zcpA-5irmA:
20.45
5zcpC-5irmA:
15.38
5zcpP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
0.97A 5zcpC-5irmA:
undetectable
5zcpN-5irmA:
undetectable
5zcpP-5irmA:
undetectable
5zcpC-5irmA:
15.38
5zcpN-5irmA:
20.45
5zcpP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
0.91A 5zcqA-5irmA:
undetectable
5zcqC-5irmA:
undetectable
5zcqP-5irmA:
undetectable
5zcqA-5irmA:
20.45
5zcqC-5irmA:
15.38
5zcqP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.46A 5zcqN-5irmA:
undetectable
5zcqP-5irmA:
undetectable
5zcqN-5irmA:
20.45
5zcqP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZGB_B_PQNB844_1
(PSAB)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 9 ILE A 723
ARG A 688
ALA A 692
LEU A 691
ALA A 687
None
1.25A 5zgbB-5irmA:
undetectable
5zgbB-5irmA:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 ALA A 297
THR A 298
GLN A 213
VAL A 210
None
0.87A 6cduA-5irmA:
undetectable
6cduE-5irmA:
undetectable
6cduA-5irmA:
15.02
6cduE-5irmA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 GLN A 213
VAL A 210
ALA A 297
THR A 298
None
0.90A 6cduH-5irmA:
undetectable
6cduI-5irmA:
undetectable
6cduH-5irmA:
15.02
6cduI-5irmA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
5 / 12 TYR A 232
HIS A 293
THR A 357
VAL A 402
TYR A 435
ADP  A1101 (-3.4A)
None
None
None
ADP  A1101 (-4.6A)
1.23A 6djzA-5irmA:
undetectable
6djzA-5irmA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 6 ASP A 359
GLN A 290
LEU A 217
SER A 218
None
1.13A 6ekuA-5irmA:
undetectable
6ekuA-5irmA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
3 / 3 LEU A 720
ASN A 805
LEU A 790
None
0.69A 6exiD-5irmA:
undetectable
6exiD-5irmA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 6 PHE A 610
LEU A 691
ALA A 687
THR A 491
None
0.88A 6f88A-5irmA:
undetectable
6f88A-5irmA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 LEU A 452
LEU A 453
LEU A 496
MET A 493
None
0.65A 6g9bA-5irmA:
undetectable
6g9bB-5irmA:
undetectable
6g9bA-5irmA:
7.21
6g9bB-5irmA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 8 LEU A 462
ASP A 492
THR A 491
TYR A 494
None
1.00A 6nknC-5irmA:
undetectable
6nknN-5irmA:
undetectable
6nknP-5irmA:
undetectable
6nknC-5irmA:
15.38
6nknN-5irmA:
20.45
6nknP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 ASP A 492
THR A 491
TYR A 494
LEU A 462
None
1.02A 6nmfA-5irmA:
undetectable
6nmfC-5irmA:
undetectable
6nmfP-5irmA:
undetectable
6nmfA-5irmA:
20.45
6nmfC-5irmA:
15.38
6nmfP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.46A 6nmfN-5irmA:
undetectable
6nmfP-5irmA:
undetectable
6nmfN-5irmA:
20.45
6nmfP-5irmA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus)
4 / 7 TRP A 470
ASP A 492
TYR A 494
HIS A 476
ADP  A1101 ( 4.8A)
None
None
None
1.47A 6nmpN-5irmA:
undetectable
6nmpP-5irmA:
undetectable
6nmpN-5irmA:
20.45
6nmpP-5irmA:
15.38