SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5irr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 12 THR A 146
GLY A 122
GLY A 120
GLY A 182
ASP A 265
 MG  A 401 ( 3.2A)
GSP  A 402 (-3.1A)
GSP  A 402 (-3.5A)
GSP  A 402 (-3.4A)
GSP  A 402 (-2.8A)
 0.93A 2b25A-5irrA:
undetectable		 2b25A-5irrA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 10 TYR A 247
ILE A 243
ILE A 295
PRO A 289
ILE A 291
 None
 1.20A 2dm6A-5irrA:
2.3
2dm6B-5irrA:
undetectable		 2dm6A-5irrA:
22.16
2dm6B-5irrA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		3 / 3 ASN A 285
ILE A 297
MET A 248
 None
 0.80A 2h42C-5irrA:
undetectable		 2h42C-5irrA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 7 PHE A 298
LEU A 305
ALA A 372
LEU A 368
 None
 1.02A 2vcvG-5irrA:
undetectable		 2vcvG-5irrA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 9 ASP A 265
VAL A 322
GLY A 122
ALA A 353
ILE A 323
 GSP  A 402 (-2.8A)
None
GSP  A 402 (-3.1A)
None
GSP  A 402 (-4.4A)
 1.01A 3el0B-5irrA:
undetectable		 3el0B-5irrA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A 373
TYR A 175
ILE A 376
LEU A 113
LEU A 126
 None
 1.28A 3vw1B-5irrA:
undetectable		 3vw1B-5irrA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		3 / 3 ASN A 204
TRP A 387
ASP A 225
 None
 0.47A 4a7tA-5irrA:
undetectable
4a7tF-5irrA:
undetectable		 4a7tA-5irrA:
18.36
4a7tF-5irrA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 6 ILE A 376
VAL A 255
LEU A 251
CYH A 231
 None
 0.84A 4asdA-5irrA:
undetectable		 4asdA-5irrA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 5 LYS A 253
LEU A 251
GLU A 250
LEU A 193
 None
 1.24A 4k4yA-5irrA:
undetectable		 4k4yA-5irrA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 4 LYS A 253
LEU A 251
GLU A 250
LEU A 193
 None
 1.27A 4k4yE-5irrA:
undetectable		 4k4yE-5irrA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 5 LYS A 253
LEU A 251
GLU A 250
LEU A 193
 None
 1.24A 4k4yI-5irrA:
undetectable		 4k4yI-5irrA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 4 LEU A 251
ILE A 200
HIS A 254
VAL A 196
 None
 1.30A 4xyzA-5irrA:
undetectable		 4xyzA-5irrA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 12 PHE A 151
PRO A 147
THR A 146
HIS A 141
GLY A 122
 None
None
MG  A 401 ( 3.2A)
GSP  A 402 (-4.2A)
GSP  A 402 (-3.1A)
 1.21A 4ydqB-5irrA:
undetectable		 4ydqB-5irrA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 7 VAL A 322
THR A 262
LEU A 130
VAL A 115
 None
 1.03A 5e4dA-5irrA:
undetectable
5e4dB-5irrA:
undetectable		 5e4dA-5irrA:
20.38
5e4dB-5irrA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 8 VAL A 310
PHE A 300
LEU A 305
VAL A 258
 None
 0.80A 5nujA-5irrA:
0.8		 5nujA-5irrA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_2
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 5 LEU A 368
VAL A 364
CYH A 231
CYH A 234
 None
 0.99A 5te0A-5irrA:
undetectable		 5te0A-5irrA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 7 THR A 146
PHE A 151
GLN A 178
MET A 195
 MG  A 401 ( 3.2A)
None
None
None
 1.38A 5u6mB-5irrA:
4.5		 5u6mB-5irrA:
19.74